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Projects: COVID-19 Disease Map
Institutions: University of Rostock
https://orcid.org/0000-0002-2486-0246Expertise: Systems Biology
Rahuman Sheriff is a Senior Project Leader (BioModels) at the European Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI), Hinxton, Cambridge, UK. He interests include mathematical modelling, development of novel tools and resources for building models, immune digital twin, quantitative imaging, single cell systems biology and chemoinformatics. He is one of the editors of Systems Biology Markup Language (SBML).
Projects: BioDynamics
Institutions: Universitat Politècnica de València
https://orcid.org/0000-0003-4144-3521Jesús Picó is Full Professor of Automatic Control at The Department of Systems Engineering and Control of the Universitat Politècnica de València (UPV). In 2013 he created the Laboratory of Synthetic Biology and Biosystems Control (SB2CLab) of the Institute of Automation and Industrial Informatics (ai2) at the UPV, the first multidisciplinary lab in Spain integrating systems and control engineers, bioinformatics and biotechnologists. His research interests are in the application of systems ...
Projects: Working Group Nicole Radde, SteaPKMod
Institutions: University of Stuttgart
https://orcid.org/0000-0002-5300-0915Currently I focuse on the integration of data into multi-scale models with statistical methods and uncertainty tracking in the research unit QuaLiPerF.
Projects: COVID-19 Disease Map
Institutions: National Institute of Informatics
https://orcid.org/0000-0001-8725-3366Expertise: Bioinformatics, Computational Systems Biology, Curation, Data analysis, Systems Biology
Tools: SBML, Python, Matlab, Systems Biology, Bioinformatics
Institutions: University of Freiburg
https://orcid.org/0000-0002-5340-3423Expertise: Bioinformatics, Databases, Genetics, Genomics, Systems Biology, Transcriptomics, Microbiology, Microarray analysis
Tools: Bioinformatics, Data analysis, Genetics, Genomics, Microarray analysis, Microbiology, Molecular Biology, Molecular biology techniques (RNA/DNA/Protein), Transcriptomics
Projects: COVID-19 Disease Map
Institutions: University of Tübingen
https://orcid.org/0000-0002-0248-6679Projects: COVID-19 Disease Map
Institutions: University Maastricht
https://orcid.org/0000-0002-7770-620XExpertise: Knowledge integration, Curation, Data Integration, rare diseases, Systems Biology, GMP, GCP, Neuroscience
Tools: wikipathways, pathvisio, Cytoscape, R, Python, Statistics
Projects: SysMO-LAB, MOSES, PSYSMO, SulfoSys, SulfoSys - Biotec, EraCoBiotech 2 nd call proposal preparation, Make Me My Model, Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population, Modelling COVID-19 epidemics, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation, Xenophiles Systems Biology, Thermodynamics, Non equilibrium thermodynamics, Book on Thermodynamics, and kinetics, Teaching Alien Biology, Outdated material, Fusion-fission-mitophagy, Stochastics and bursting
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, VU University Amsterdam, University of Amsterdam, Systems Biology Amsterdam
https://orcid.org/0000-0002-0443-6114Systems Biologist at University of Amsterdam, Free University Amsterdam, University of Manchester, Infrastructure Systems Biology.NL (ISBE.NL), Systems Biology Amsterdam.
Projects: C19DM - Macrophage logical model, COVID-19 Disease Map
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-9044-4742Expertise: Systems Biology, Bioinformatics, Immunology, Molecular Biology
Tools: GINsim, Cytoscape, Computational and theoretical biology, Databases, data modeling
Projects: COVID-19 Disease Map
Institutions: University of Surrey
https://orcid.org/0000-0001-5640-7422Reader (Professor) of Systems Biology; Executive Director for the International Society of Systems Biology (ISSB); Editor-in-Chief of Current Opinion in Systems Biology (Elsevier).
Projects: COVID-19 Disease Map
Institutions: Fundación Progreso y Salud
https://orcid.org/0000-0003-2632-9587Projects: COVID-19 Disease Map
Institutions: MRC-University of Glasgow Centre for Virus Research
https://orcid.org/0000-0003-0411-4497Expertise: Modeling, Bioinformatics, Systems Biology
Tools: R
Bioinformatician / Computational Biologist
Projects: CoolWine
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-3485-1634Expertise: Systems Biology
Tools: network theory, FBA, R, Python, Statistics
PhD candidate working on the CoolWine project
Projects: COVID-19 Disease Map
Institutions: Biomax Informatics AG
Projects: COVID-19 Disease Map
Institutions: University of Tübingen
https://orcid.org/0000-0003-3851-9978Expertise: Curation, Computational Systems Biology, Constraint-based Modelling, Systems Biology
Tools: SBML, Python, cobrapy toolbox, CellDesigner, libSBML, jupyter notebooks
Projects: COVID-19 Disease Map
Institutions: University of Tübingen
https://orcid.org/0000-0002-1240-5553Expertise: Systems Biology, Computational Systems Biology, Databases, Dynamic modelling, Java, Mathematical modelling, Metabolic Engineering, Disease Maps, Curation, Modeling, Data Integration, Constraint-based Modelling, Parameter estimation
Tools: SBML, SBGN, SBGNML, JSBML, Jupyter, Python, cobrapy toolbox, SBSCL, InSilico, Kinetic Modeling
Andreas Dräger is the assistant professor for Computational Systems Biology of Infection and Antimicrobial-Resistant Pathogens at the University of Tübingen in Germany. His group aims to combat the spreading antibiotics resistances by using mathematical modeling and computer simulation of bacterial systems up to entire microbiomes and host-pathogen interactions. In doing so, his group actively contributes to the advancement of various COMBINE standards.
Expertise: Systems Biology, SBML, Java, Python, Machine Learning, Mathematical modelling, SBGN, Curation
Tools: CellDesigner, SBML, SBGN
Projects: HUMET Startup, COVID-19 Disease Map, C19DM-Neo4j
Institutions: European Institute for Systems Biology and Medicine, Luxembourg Centre for Systems Biomedicine (LCSB)
https://orcid.org/0000-0001-7137-4171Expertise: Systems Biology, Systems Medicine, Disease Maps, Systems Biology Graphical Notation
Tools: SBGN, CellDesigner, SBGN-ED, Newt Editor
Projects: COVID-19 Disease Map
Institutions: University of Applied Sciences Mittweida
https://orcid.org/0000-0002-1788-9593Expertise: standards, Systems Biology, Bioinformatics, Computational Systems Biology, Java, Python, SBGN
Tools: SBGN-ED
Projects: COVID-19 Disease Map
Institutions: Yenepoya University
Expertise: Biochemistry, Data analysis, Systems Biology, Data Integration
Tools: Proteomics, Systems Biology, Molecular Biology, Bioinformatics, Data Integration
Projects: COVID-19 Disease Map
Institutions: Universität Konstanz
Projects: COVID-19 Disease Map
Institutions: Barcelona Supercomputing Center
https://orcid.org/0000-0002-7696-1241I completed my BSc in Biology and MSc in Cell Biology by the University of Valencia. During my last undergrad year I participated in synthetic biology’s iGEM competition where I dove in the use of models in Biology, which pushed me to pursue a PhD in the Department of Applied Mathematics in the Technical University of Valencia.
My research on Metabolic Engineering of hydrogen in cyanobacteria led me to be visiting researcher at Uppsala University, Denmark Technical University and EMBL Heidelberg. ...
Expertise: Biochemistry, Cell biology, Data analysis, Dynamic modelling, Systems Biology, Image analysis, Genetics, Molecular Biology, R, SBML, Curation, Quantitative Biology, Physical Chemistry
Tools: Biochemistry and protein analysis, Bioinformatics, Systems Biology, SBML, R, ODE, Molecular biology techniques (RNA/DNA/Protein), Genetics, Dynamic modelling, Computational and theoretical biology, CellDesigner, Parameter estimation
Projects: COVID-19 Disease Map
Institutions: Luxembourg Centre for Systems Biomedicine (LCSB)
https://orcid.org/0000-0002-8278-240XExpertise: Biological knowledge managament, Systems Biology, Biocuration
Tools: CellDesigner, Cytoscape, Python, Shell scripting, NetworkX, Protein2GO
Tools: Systems Biology, R
Projects: ComPASs - Common Pathways in Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA), miRiAD - exploring the role of microRNAs in T cell function and anti-viral defence, LungCARD - Blood test for clinical therapy guidance of non-small cell lung cancer patients
Institutions: RNA Systems Biology Lab - BioISI/FCUL
Expertise: Bioinformatics, Systems Biology
Expertise: biocatalysis, Molecular Biology, Systems Biology
Tools: screening assays, enzymatic synthesis, enzyme engineering
Professor- University Clermont Auyvergne (UCA) - Institute of Chemistry of Clermont-Ferrand (ICCF)
Projects: PoLiMeR - Polymers in the Liver: Metabolism and Regulation
Institutions: University of Groningen
I work as a project manager for the Innovative Training Network PoLiMeR - Polymers in the LIver: Metabolism and Regulation funded by the EU. In addition I am a project manager for the UMCG Research BV where I support scientist in the pre-award phase with writing their proposals and in the post-award phase with managing their awarded projects.
Projects: SulfoSys, SulfoSys - Biotec, HOTSOLUTE, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers
Institutions: University Duisburg-Essen, Universitity Duisburg-Essen
https://orcid.org/0000-0002-9905-541XHead of the group of Molecular Enzyme Technology and Biochemistry (Faculty of Chemistry) at the University of Duisburg-Essen. My research interest is on archaeal physiology with a special focuss on the central carbohydrate metabolism of (hyper)thermophilic Archaea and its regulation. The aim is to gain a systems level understanding by the combination of modern highthrouput analyses with classical biochemistry and molecular biology. Archaea possess many novel enzymes and pathways and our aim is ...
Projects: pISA-tree, HYp - Spatiotemporal analysis of hypersensitive response to Potato virus Y in potato, INDIE - Biotechnological production of sustainable indole, _p_stRT, ADAPT - Accelerated Development of multiple-stress tolerAnt PoTato, tst, tst2
Institutions: National Institute of Biology, tst
https://orcid.org/0000-0002-1669-6482Expertise: Molecular Biology, Statistics, Bioinformatics, Mathematical and statistical modeling, Programming, Data analysisMathematical modellingBioinformaticsSystems biology, Data Management, Data analysis, Visualization, Data Integration, Computational Biology
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Molecular Biology, Python, R, Systems Biology, Data Integration
Computational Biologist and Biostatistician at Department of Biotechnology and Systems Biology, National Institute of Biology (NIB)
Institutions: Latvia University of Agriculture
Expertise: Python, Systems Biology, Dynamic modelling, Mathematical modelling
Tools: COBRA toolbox, cobrapy toolbox, Python, SBML, Copasi, Computational Systems Biology
Projects: SUSPHIRE - Sustainable Bioproduction of Pheromones for Insect Pest Control in Agriculture, INDIE - Biotechnological production of sustainable indole, ADAPT - Accelerated Development of multiple-stress tolerAnt PoTato
Institutions: National Institute of Biology
https://orcid.org/0000-0003-4776-7164Projects: HYp - Spatiotemporal analysis of hypersensitive response to Potato virus Y in potato, pISA-tree, MOA - Multiomics analysis of potato response to Potato virus Y (PVY) infection, SUSPHIRE - Sustainable Bioproduction of Pheromones for Insect Pest Control in Agriculture, INDIE - Biotechnological production of sustainable indole, FAIRDOM user meeting, _p_stRT, ADAPT - Accelerated Development of multiple-stress tolerAnt PoTato
Institutions: National Institute of Biology
https://orcid.org/0000-0001-5906-8569PhD in Biotechnology, Research Associate at Department of Biotechnology and Systems Biology, National Institute of Biology
Projects: NTNU Health Druglogics, Colosys
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-3609-8674Expertise: Systems Biology, Computational Biology
Prof. Dr. Kathrin Thedieck MESI-STRAT Coordinator Leader WP8 – Project Coordination
Projects: INCOME, COVID-19 Disease Map
Institutions: ICB Helmholtz Center Munich, University of Bonn
https://orcid.org/0000-0002-4935-3312Expertise: Mathematical modelling, Systems Biology, Parameter estimation
I studied Engineering Cybernetics at the University of Stuttgart and the University of Wisconsin, Madison. After my graduation, I started my PhD studies in systems biology for which I received a Ph.D. degree in 2013. A few months later I became team leader at the Institute of Computational Biology at the Helmholtz Zentrum München. Since August 2015, I lead an independent junior research group at the Helmholtz Zentrum München.
My research focuses on the development of methods for the data-driven ...
Projects: Millar group, PlaSMo model repository, PHYTOCAL: Phytochrome Control of Resource Allocation and Growth in Arabidopsis and in Brassicaceae crops, Light and plant development, Light control of leaf development, Toggle switch, Reduce Complexity (RCO) reconstruction, Model Driven Prime Editing, PULSE 2.0, Plant optogenetics
Institutions: University of Edinburgh, Heinrich Heine University of Düsseldorf
https://orcid.org/0000-0002-7975-5013Projects: Millar group, TiMet, PHYTOCAL: Phytochrome Control of Resource Allocation and Growth in Arabidopsis and in Brassicaceae crops, POP - the Parameter Optimisation Problem, Regulation of flowering time in natural conditions, PlaSMo model repository
Institutions: University of Edinburgh
https://orcid.org/0000-0003-1756-3654Projects: WineSys, INBioPharm, BioZEment 2.0, CoolWine, Auromega
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-9125-326XExpertise: Systems Biology
Tools: network theory
Projects: PHYTOCAL: Phytochrome Control of Resource Allocation and Growth in Arabidopsis and in Brassicaceae crops, Light and plant development, Light control of leaf development
Institutions: University of Edinburgh
https://orcid.org/0000-0003-0737-2408Expertise: arabidopsis thaliana, caenorhabditis elegans, circadian rhythms, chronobiology, Transcriptomics, splicing, alternative splicing, R, photobiology, plant architecture, leaf development
Tools: Molecular Biology, Molecular biology techniques (RNA/DNA/Protein), R, Systems Biology, Transcriptomics, Bioinformatics, Databases, Genetics, Plant biology, C. elegans biology
Projects: SAFE-Aqua, Biomics Projects
Institutions: Institut Pasteur
https://orcid.org/0000-0001-6286-1138Projects: MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, DigiSal, WURSynBio, INDIE - Biotechnological production of sustainable indole
Institutions: Wageningen University & Research
https://orcid.org/0000-0001-5845-146XExpertise: Metabolic modelling, Systems Biology, Transcriptomics, R, SBML
Associate Professor at Wageningen University & Research
Expertise: Mathematical modelling, Systems Biology, Parameter estimation
Tools: Dynamic modelling, Matlab, ODE, Parameter estimation
Projects: EmPowerPutida, COVID-19 Disease Map
Institutions: Wageningen University & Research, University Maastricht
https://orcid.org/0000-0003-3091-3962Expertise: Systems Biology, Mathematical modelling, Biotechnology, Synthetic Biology, Metabolic Engineering, metabolism, Metabolic Networks, SARS-CoV 2, COVID-19, Pathway Curation, Pathway Analysis, Network Analysis
Tools: Matlab, Computational Systems Biology, Flux balance analysis, omics analysis, Python, R, Constraint-based analysis
My research interest is in studying cellular and molecular pathways of COVID-19 disease.
Projects: EmPowerPutida
Institutions: LifeGlimmer GmbH
Expertise: Bioinformatics, Systems Biology, Transcriptomics, R, Genomics, Proteomics, Databases, Data Integration
Tools: Bioinformatics, Molecular Biology, Computational Systems Biology
Computational Biologist and App Designer @LifeGlimmer
Projects: MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, WURSynBio
Institutions: Wageningen University & Research
https://orcid.org/0000-0001-7049-5334Expertise: Bioinformatics, Systems Biology, Agent-based modelling, Dynamic modelling, Python, Java, R, pathogen host interaction, Molecular Biology
Tools: Copasi, libRoadrunner, Python, R, semantic web
I am a researcher (PhD student) working at Wageningen University & Research as bioinformatician and modeller. I am working as part of the MycoSynVac (http://www.mycosynvac.eu/) project on dynamic modelling of central carbon metabolism in M. pneumoniae, to be extended to full dynamic modelling of metabolism to be implemented in a whole cell model. I am also looking into possibilities to improve standards in model generation using semantic technologies, improving automatic generation, annotation ...
Expertise: Transcriptomics, Systems Biology, plant, Data Integration
Projects: SBEpo - Systems Biology of Erythropoietin
Institutions: German Cancer Research Center (DKFZ)
https://orcid.org/0000-0002-0971-2309Expertise: Mathematical modelling, Single Cell analysis, Cell biology, Molecular Biology
Tools: Biochemistry, Systems Biology, Matlab, R
Projects: HUMET Startup, COVID-19 Disease Map
Institutions: Bilkent University
https://orcid.org/0000-0002-7153-0784Expertise: Bioinformatics, Systems Biology, SBGN standard, Network Visualization, Graphical Editors
Tools: SBGNViz, cBioPortal, PathwayMapper, ChiBE, Newt Editor
Associate Professor for Systems Biomedicine, Luxembourg Centre for Systems Biomedicine, University of Luxembourg
Projects: HUMET Startup, EraCoBiotech 2 nd call proposal preparation, COVID-19 Disease Map
Institutions: geneXplain GmbH
https://orcid.org/0000-0001-6775-2467Expertise: Systems Biology, promoters and anhancers, gene regulation, signal transduction, drug targets
Tools: geneXplain platform, BioUML, R, c++
Alexander Kel received his Ph.D. in Bioinformatics, Molecular Biology and Genetics in 1990. He studied biology and mathematics at Novosibirsk State University and obtained his M.S. in biology with special focus on mathematical biology in 1985. He worked for 15 years at the Institute of Cytology and Genetics, Russia (ICG) holding positions as a programmer, scientist, senior scientist and Vice-Head of the Laboratory of Theoretical Molecular Genetics. In 1995, he won the Academician Belaev Award. ...
Projects: HUMET Startup, COVID-19 Disease Map
Institutions: Centro de Investigación Príncipe Felipe, Fundación Progreso y Salud
https://orcid.org/0000-0003-3318-120XExpertise: Bioinformatics, Data Management, Mathematical modelling, Genomics, Genetics, Transcriptomics, Systems Biology, Microarray analysis, Data Integration
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Genetics, Genomics, R, Systems Biology, Transcriptomics, Java
My scientific interests revolve around functional genomics, systems biology and the development of algorithms and software for the analysis of high-throughput data (mainly, but not restricted to, Next Generation Sequencing) and its application to the relationship between genotype and phenotype, mainly oriented to personalized and precision medicine. I am especially interested in the study of disease mechanisms and drug action mechanisms, drug repositioning and the definition of mechanism-based ...
Expertise: chromatin, Epigenetics, nuclear organisation, DNA repair
Tools: quantitative microscopy, Biochemistry, Systems Biology, Cell biology
POSITION I am an emeritus professor in Biochemistry at the University of Amsterdam (retired 2010).
RESEARCH My research focussed on the human chromatin in its natural environment, i.e. the nucleus of cultured living human cells. Aspects, such as the dynamic folding of the chromatin fiber inside the nucleus and local chemical modification of histones and DNA at genetic loci, are the physical and chemical basis for epigenetic regulation of gene expression. In my group we worked parallel on human ...
I am had of the Research Group PiDOMICS which aims at the identification of human biomarkers for fungal infection using omics-data. Moreover, I am PI Infrastructure project of the Collaborative Research Center / Transregio 124 Pathogenic fungi and their human host: Networks of Interaction - FungiNet. Thereby my expertise is the implementation and usage of pipeline for OMICS (genome, transcriptome, protoem) data analysis, as well as data-warehouses for visualizing these data.
Projects: FAIRDOM user meeting
Institutions: SYSBIO - Centre of Systems Biology
https://orcid.org/0000-0002-6566-2844Expertise: Bioinformatics, Data Management, Databases, Microarray analysis, Systems Biology
Projects: FAIRDOM user meeting
Institutions: Peter MacCallum Cancer Centre
Expertise: Systems Biology, Transcriptomics, Genomics
Tools: Systems Biology, Transcriptomics, Computational Systems Biology, Bioinformatics, R
Projects: FAIRDOM user meeting
Institutions: KAIST
Expertise: Cell biology, Molecular Biology, Cancer, Stem cell
Tools: Boolean modeling, Systems Biology
Projects: IMOMESIC, FAIRDOM user meeting, Chronic Liver Disease Progression (LiSyM-DP - Pillar II), Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF - Pillar III)
Institutions: German Cancer Research Center (DKFZ)
https://orcid.org/0000-0002-3706-7386Expertise: Mass spectrometry (LC-MS/MS), Proteomics, Systems Biology
PhD student @ "Quantitative Microbial Phenotyping" Institute of Bio- and Geosciences, IBG-1: Biotechnology Forschungszentrum Jülich GmbH 52425 Jülich, Germany
Team leader "Quantitative Microbial Phenotyping" Institute of Bio- and Geosciences, IBG-1: Biotechnology Forschungszentrum Jülich GmbH 52425 Jülich, Germany
POSITION Prof. Dr. Natal van Riel is Professor in Computational Modelling at the Academic Medical Center - University of Amsterdam (AMC - UvA) and Associate Professor in Systems Biology and Metabolic Diseases at the Department of Biomedical Engineering of the Eindhoven University of Technology (TU/e).
RESEARCH My research applies mathematical modelling and computation to study metabolic diseases, in particular Metabolic Syndrome and co-morbidities. Systems biology approaches are developed for ...
Projects: Kinetics on the move - Workshop 2016, COVID-19 Disease Map
Institutions: Kinetics on the move Workshop at HITS, Luxembourg Centre for Systems Biomedicine (LCSB)
https://orcid.org/0000-0003-1473-370XExpertise: Data Management, Molecular Biology, Systems Biology, Curation
Tools: SBGN, CellDesigner, MIRIAM, SBML, Data Science
Scientific Project Manager at Luxembourg Centre for Systems Biomedicine, University of Luxembourg http://lcsb.uni.lu
Projects: Kinetics on the move - Workshop 2016, CausalDB, COMBINE Multicellular Modelling, Colosys, NTNU Health Druglogics
Institutions: Kinetics on the move Workshop at HITS, Norwegian University of Science and Technology
https://orcid.org/0000-0003-4639-4431Expertise: Bioinformatics, Systems Biology, SBGN standard
Systems biology for salmon farming is what I do. I lead the DigiSal project (http://tinyurl.com/digisal), whose full title is "Towards the Digital Salmon: From a reactive to a pre-emptive research strategy in aquaculture". DigiSal is part of Digital Life, the first call dedicated to systems biology by the Research Council of Norway. I'm also one of the lead modellers in GenoSysFat (http://tinyurl.com/genosysfat), working to improve the omega-3 content of salmon farmed on sustainable feeds by ...
Projects: FAIRDOM, Early Metabolic Injury (LiSyM-EMI - Pillar I), Chronic Liver Disease Progression (LiSyM-DP - Pillar II), Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF - Pillar III), LiSyM Core Infrastructure and Management (LiSyM-PD), Liver Function Diagnostics (LiSyM-LiFuDi - Pillar IV), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), Kinetics on the move - Workshop 2016, Example use cases, FAIRDOM user meeting, MS_DILI, COMBINE Multicellular Modelling, FAIRDOM & LiSyM & de.NBI Data Structuring Training, EnzymeML, GMDS Project Group "FAIRe Dateninfrastrukturen für die Biomedizinische Informatik", FAIRDOM Community Workers, COVID-19 Disease Map, COVID-19 related studies and tools in Germany, nfdi4health - German National Research Data Infrastructure for Personal Health Data, ModeleXchange initiative, SDBV/HITS, EDITH (Ecosystem Digital Twins in Health) test project
Institutions: Heidelberg Institute for Theoretical Studies (HITS gGmbH)
https://orcid.org/0000-0002-8683-7084Data management and standardization expert for systems biology and systems medicine, responsible for the data management user requirements and user contacts within the German LiSyM network (Liver Systems Medicine: http://lisym.org/) and associated to the FAIRDOM team. Involved in different standardization initiatives and committees, i.e. COMBINE (http://co.mbine.org), ISO/TC 276 Biotechnology (https://www.iso.org/committee/4514241.html), European COST action CHARME (http://www.cost-charme.eu) and ...
Expertise: Systems Biology, Dynamic optimization., Metabolic Networks
Projects: ZucAt, Modelling COVID-19 epidemics
Institutions: Institute of Cytology and Genetics, Novosibirsk State University
Expertise: Systems Biology, molecular genetic systems, gene networks, gene expression, Modeling
Tools: Java, Vaadin, Kinetic Modeling
I am staff scientist in the lab of molecular-genetic systems at the Department of Systems Biology, Institute of Cytology and Genetics SB RAS and Postdoc Research Fellow at San Diego State University. My research focus is dynamical modeling of gene network functioining.
Projects: Not specified
Institutions: Not specified
Expertise: Systems Biology, marine, microbiomics
Tools: Pathway Tools
Projects: SysMetEx
Institutions: Universitity Duisburg-Essen
My research is intended to contribute to the elucidation of the physiological and molecular processes involved in the biofilm formation of acidophilic leaching bacteria with emphasis in their cell-cell communication mechanisms. In SysMetEx, our role is to understand biofilm formation at a microscopical and OMICS levels, in order to optimize it.
Projects: MetApp, INBioPharm, SYSTERACT, Auromega
Institutions: SINTEF
https://orcid.org/0000-0002-1221-8598Research scientist
Projects: SulfoSys - Biotec, ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Otto-von-Guericke University Magdeburg, University of Gothenburg
https://orcid.org/0000-0001-6971-2530Expertise: Signalling networks, dynamics of biological networks., Databases, Data analysis, Systems Biology, Model selection, Identifiability, Cellular Senescence, Cell Cycle, Dynamic Systems, Image processing, Image analysis, Parameter estimation
Tools: ODE, FACS, Model selection, Fluorescence and confocal microscopy, Identifiability analysis, Parameter estimation
My group investigates dynamic regulation and control mechanisms of cellular signal transduction networks by a combination of theoretical, experimental and computational methods. We seek to make sense of our biological data with the help of mathematical models, which ideally enable us to make valid predictions for new experiments, thereby generating novel biological insights.
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Institute of Cytology and Genetics
I am a biomodeler, PhD student. Actually, I've graduated from Novosibirsk State University on two specialities: my bachelor diploma is done in computer science and the master thesis is defended in information biology. So, I'm kind of drifting towards biology. I am a part of the Haploid Evolutionary Constructor project. Our research group studies are dedicated to the simulation of prokaryotic communities. Personally, I am involved into the simulation of spatially distributed bacterial communities ...
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: University of Goettingen
Expertise: Systems Biology, High-throughput data analysis, Data Integration
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Universität Konstanz
Expertise: Molecular Biology, Systems Biology, Mathematical modelling
Tools: quantitative western blot analysis, Molecular Biology, Java, octave, R, ODE
I studied Life Science (which is similar to chemical biology) at the University of Konstanz and became interested in Bioinformatics, Systems Biology and quantitative analyses during my Master's. In my PhD project I combine experimental analyses with modeling and parameter estimation approaches to quantitatively analyse regulation of apoptosis at the level of the Bcl-2 protein family.
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Radboud University Nijmegen
Expertise: Molecular Biology, Microbiology, Escherichia coli, Systems Biology
I am a first year graduate student in the lab of Prof. Wilhelm Huck at the Radboud University Nijmegen. I am working on a project to create an artificial cell. This involves implementing complex genetic networks in cell-free systems which are far from equilibrium. My project involves designing, quantifying, modeling such networks. I am a molecular biologist by training and have basic modeling skills. I am looking to expand my skill-set to include microscopy, microfluidics and a little bit of ...
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Imperial College London
I am a PhD student in the Theoretical Systems Biology group, based at Imperial College London. The aim of my PhD is to understand how noise can be the driving force of decision-making processes (differentiation, self-renewal, apoptosis or tumorgenesis), and what are our chances to control them. So far I have been working on method development for stochastic models, a moment closure framework and a stochastic reachability method, to look into cell-to-cell-variability.
Projects: SulfoSys, SulfoSys - Biotec, Glucose metabolism in cancer cell lines
Institutions: University Duisburg-Essen, Stellenbosch University
Projects: SysMO DB, Whole body modelling of glucose metabolism in malaria patients, Manchester Institute for Biotechnology, FAIRDOM, ICYSB 2015 - International Practical Course in Systems Biology, GenoSysFat, DigiSal, FAIRDOM user meeting
Institutions: University of Manchester - Department of Computer Science, Manchester Centre for Integrative Systems Biology, University of Manchester
https://orcid.org/0000-0003-4958-0184Interested in systems + synthetic biology, biotechnology, mountaineering, swimming, running, and the occasional cup of tea. Once diagnosed as an ENFP.
Expertise: Mathematical modelling of biosystems and bioprocesses, Optimal experimental design, Systems Biology, sensitivity analysis, Dynamic optimization., Dynamics and Control of Biological Networks, Parameter estimation
Tools: ODE, Partial differential equations, Matlab, differential algebraic equations, Stochastic models, Computational Systems Biology, Deterministic models, Dynamic modelling, Parameter estimation
I am a postdoctoral researcher in the group of Julio Banga. My research is focused on computational systems biology with particular attention to the mathematical modelling of biosystems and bioprocesses. Some of the topics we address are:
- Parameter estimation
- Model identifiability
- Global sensitivity analysis
- Optimal experimental design
- Dynamic optimization
- Robust control of diffusion-reaction systems
Institutions: University of Tuebingen, University of Tübingen
Projects: BaCell-SysMO
Institutions: University of Rostock
Expertise: Mathematical modelling, Bacillus subtilis, Deterministic modelling of gene regulation networks, stress responses, Systems Biology, sensitivity analysis, Dynamics and Control of Biological Networks, Parameter estimation
Tools: Biochemistry, Computational and theoretical biology, ODE, Matlab, linux, Stochastic models, Deterministic models, Dynamic modelling
Modelling of the general stress response activation cascade of sigB in B. subtilis in response to starvation.
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Microbiology, Genetics, Molecular Biology, Bacillus subtilis, translational control of gene expression, sporulation, phenotypic heterogeneity, bistability, gene regulation, stress responses, Signal transduction in Gram-negative bacteria; Synthetic Microbiology; Single cell gene expression; Regulatory networks; biochemistry; histidine ki..., regulation of gene expression, Systems Biology
Tools: Microbiology, Genetics, Molecular Biology, Genetic analysis, Genetic modification, Model organisms, Single Cell analysis, PCR, Fluorecence based reporter gene analyses/single cell analyses, Molecular biology techniques (RNA/DNA), time lapse microscopy, Time-lapse fluorescence microscopy Flow cytometry
Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
Projects: SUMO
Institutions: University of Stuttgart
Expertise: Mathematical modelling, Data Management, Systems Biology, Parameter estimation
Tools: SBML, ODE, Matlab, Mathematica
Former: PhD student as research associate at the Institute for System Dynamics (ISYS), Universität Stuttgart, Germany. Engineering background→modelling, identification and analyses. Detailed kinetic modelling, identification and analysis of the TCA cycle (tricarboxylic acid cycle, citric acid cycle) and the ETC (electron transport chains, respiratory chains) of Escherichia coli. One of the SysMO-DB pals for SUMO. Now: Industrial affiliation
Projects: SUMO
Institutions: University of Stuttgart
From 2005 to 2008 I was group leader at the Institute for System Dynamics at the University of Stuttgart. Since 2008 I am now Professor of Systems Biology at the University of Luxembourg.
The research of the Systems Biology Group at the University of Luxembourg is focussed in the area of experimental and theoretical systems biology. We are applying different modelling techniques (mainly ODE and logical) to biological systems to develop suitable computational models. The analysis of these models ...
Projects: BaCell-SysMO
Institutions: University of Newcastle
Expertise: Microbiology, Molecular Biology, Gram positive bacteria (Bacillus, Systems Biology, Genetics)
Tools: Microbiology, Molecular Biology, Biochemistry and protein analysis, Cell biology, Genetic analysis, Genomics, Transcriptomics, Proteomics, Model organisms, Proteomics (2D-PAGE), gene regulation, DNA technology RNA technology Protein analysis Fermentation Mutagenesis, molecular biological techniques (RNA/DNA techniques), protein interaction studies
Optimisation of Bacillus subtilis for the secretion of heterologous proteins Therapeutic proteins (including those required for experimental purposes and clinical trials) are major products of biomanufacturing processes and considerable time and expense are expended to maximise the yield and quality of proteins produced in heterologous hosts. The production host of choice is the Gram-negative bacterium Escherichia coli for which many strains and expression systems have been developed. However, ...
Projects: COSMIC, BaCell-SysMO
Institutions: University of Rostock
Expertise: Mathematical modelling, dynamics of biological networks, Physics, bistability, Systems Biology, Data analysis, Statistical Physics, Dynamics and Control of Biological Networks
Tools: Computational and theoretical biology, ODE, Matlab, Mathematica, differential algebraic equations, Stochastic models, C programming, Computational Systems Biology, Dynamic modelling, Data Modelling
Modelling of cellular signalling, Dynamic Motifs and Feedback, Quantitative Measures, Theoretical Aspects of Modelling Biological Systems
Projects: BaCell-SysMO
Institutions: University of Stuttgart
Expertise: Microbiology, Biochemistry, Mathematical modelling, Bacillus subtilis, Mathematical modelling of biosystems and bioprocesses, stress responses, Systems Biology, Nonlinear Dynamics, carbon metabolism, Signalling networks, Metabolic Networks
Tools: Computational and theoretical biology, ODE, Matlab, Mathematica, Fermentation, Chromatography, continuous cultivation, Enzyme assay, Computational Systems Biology, Deterministic models, Dynamic modelling, fed-batch cultivation
I am a biologist in the lab of Prof. Reuss at the University of Stuttgart and I am working in the field of biotechnology and mathematical modelling.
Projects: SUMO
Institutions: University of Sheffield
I am a first year PhD student, working with Professor Robert Poole (University of Sheffield), Professor Jeff Green (University of Sheffield) and Dr Jamie Wood (University of York) using a systems biology approach to study respiration in Escherichia coli.
Projects: PSYSMO, MOSES, COSMIC, BaCell-SysMO
Institutions: University of Stuttgart
Expertise: Reactor models, rapid sampling experiments, Systems Biology, Mathematical modeling, Regulatory Networks, Dynamics and Control of Biological Networks
Tools: Fermentation, stimulus response experiments, evaluation of process dynamics, continuous cultivation, Computational Systems Biology, including:- Dynamic modelling- Parameter estimation- Optimal experimental design- Dynamic optimization, Dynamic modelling, In silico Metabolic Network Analysis, fed-batch cultivation
Professor for Biochemcial Engineering, University Stuttgart
Projects: COSMIC
Institutions: University of Nottingham
Expertise: Microbiology, Genetics, Molecular Biology, Systems Biology, Synthetic Biology
Tools: Genetic analysis, Genetic modification
I'm an 'experimentalist' (molecular microbiologist) Postdoc working on regulation and peptide signaling in Clostridium acetobutylicum. I'm also a SysMO-DB PAL (Product Application Liason) for COSMIC, working on data management including standards and integration with SysMO SEEK.
Projects: SulfoSys, PSYSMO, SulfoSys - Biotec, EbN1 Systems Biology
Institutions: University of Braunschweig
Projects: COSMIC
Institutions: University of Rostock
biomathematician, PhD student at the University of Rostock, Systems Biology Group Rostock
Projects: PSYSMO, DigiSal, GenoSysFat, HUMET Startup, EmPowerPutida, MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, SAFE-Aqua, INDIE - Biotechnological production of sustainable indole
Institutions: Helmholtz Centre for Infection Research Braunschweig, Wageningen University & Research
Expertise: Microbiology, Mathematical modelling of biosystems and bioprocesses, Optimal experimental design, Systems Biology, Biotechnology
Tools: Bioinformatics, Genetic modification, Proteomics, Fermentation, Microarray analysis, Computational Systems Biology, Metabolic Engineering, microbiology techniques, reverse engineering, computational platform development, metabolic netwlrk visualization
My research activities has been to use mathematical models and Computational Biology to answer biological questions, intertwining in silico and experimental methods at all stages. I have a strong interest in exploring the interfaces between Fundamental Biology and bona fide Engineering, specifically in the realm of environmental and industrial problems. The research goals of my group are to contribute to the elucidation of mechanisms underlying basic cellular processes, evolution and ecological ...
Projects: MOSES, ExtremoPharm, ZucAt, GenoSysFat, DigiSal, EraCoBiotech 2 nd call proposal preparation, FAIRDOM & LiSyM & de.NBI Data Structuring Training
Institutions: University of Stuttgart, University of Hohenheim, Norwegian University of Life Sciences, Norwegian University of Science and Technology
https://orcid.org/0000-0002-7973-9902Expertise: Biochemistry, coupling metabolome and environome, rapid sampling experiments, Systems Biology, carbon metabolism, Stoichiometric modelling, Proteomics, Metabolomics, yeast, fungi, Dynamics and Control of Biological Networks
Tools: Biochemistry and protein analysis, Metabolomics, Matlab, Fermentation, Chromatography, Material balance based modeling, stimulus response experiments, continuous cultivation, Enzyme assay, Mass spectrometry (LC-MS/MS), HPLC, GC and LC/MS analysis of metabolites, ODE, Parameter estimation
I've become a SysMO DB PAL for MOSES project in 2007 being a post-doc in lab of Prof. Matthias Reuss at University of Stuttgart. In the MOSES project, our major efforts were in the experimental data acquisition for dynamic model of primary carbon and anaerobic energy metabolism in yeast. The model implements prediction of perturbations of two types: glucose pulse and temperature jump. We implement “stimulus-response” methodology for the unraveling the dynamic structure of the network and to ...
Projects: COSMIC
Institutions: Beuth University of Applied Sciences Berlin
I am a biotechnologist with main focus on theoretical studies. Currently, I am working on the implementation of a parameter estimation algorithm on GPUs to reduce the computational burden of huge ODE systems. I am a PAL and I am looking forward to communication with other SYSMO members.
Projects: COSMIC
Institutions: Wageningen University & Research
Expertise: Microbiology, Genetics, Molecular Biology, Systems Biology, Anaerobic Microbiology, Clostridial Genetics, Metabolic Engineering, Synthetic Biology, bacterial metabolism, carbon metabolism, Clostridium
Tools: Microbiology, Molecular Biology, Chromatography, Molecular biology techniques (RNA/DNA/Protein)
I'm an experimentalist 'Pre-doc' (I still have to finish my PhD thesis) and my work on the COSMIC project will focus on setting up a metabolomic analysis method for Clostridium acetobutylicum. In the past I have worked on metabolic engineering of the same organism by disrupting genes to asses their impact on acid and solvent formation. I'm looking forward to joining the COSMIC web-community. It hopefully will all us to stay in touch and update each other on advances in the (computer)lab.
Projects: STREAM, SilicoTryp
Institutions: University of Groningen
Expertise: Transcriptomics, Metabolomics, Systems Biology
I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at ...
The dataset presents mathematical models of the gene regulatory network of the circadian clock, in the plant Arabidopsis thaliana. The work will be published as Urquiza-Garcia, Molina, Halliday and Millar, title "Abundant clock proteins point to missing molecular regulation in the plant circadian clock", in Molecular Systems Biology, 2025.
Starting from the U2019.3 and U2020.3 models, this project rescales parameters to match protein levels that were predicted using a simple model from the TiMet ...
Submitter: Andrew Millar
Studies: Construction of NanoLUC-tagged plants, Estimating DNA-binding affinities for Arabidopsis proteins, Measuring absolute levels of clock proteins with calibrated NanoLUC assays, Predicting absolute levels of clock proteins with a simple model, Recalibrating the clock models for absolute protein levels, to create mo..., Reproducibility documentation
Assays: Clock protein number determination with NanoLUC calibration, Clock proteins NanoLUC fusion raw data, Gatway maps of genomic regions of clock genes, In vivo bioluminescence of clock protein-NanoLUC fusions: example experi..., Jupyter notebook Predicting Protein Numbers, Propagating scaling factors into model parameters for U2019.4->U2019.5 a..., Protein level time series, Python packages, Reproducibility tool set, Selection of complemented transgenic lines, TiMet RNA timeseries data, promoter binding affinity calculations on the genome based on PBMs and E...
Snapshots: Snapshot 1
Assay: _A_05_BUSCO Short Name: 05_BUSCO Assay Class: DRY Assay Type: BUSCO Title: BUSCO post filtering and reassignment Description: BUSCO post filtering and reassignment pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /output/output.tar, /scripts/scripts.tar, /transfer/transfer.zip
Snapshots: Snapshot 1
Assay: _A_04_TransRate Short Name: 04_TransRate Assay Class: DRY Assay Type: TransRate Title: TransRate post filtering and reassignment Description: TransRate post filtering and reassignment pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /output/output.tar, /scripts/run_TransRate_commands.sh
Snapshots: Snapshot 1
Assay: _A_03.2_components Short Name: 03.2_components Assay Class: DRY Assay Type: components Title: Components: tr2aacds headers, cdhit-2d Description: Components: tr2aacds headers, cdhit-2d; post-filtering redefinition of paralogue clusters pISA Assay creation date: 2019-10-22 pISA Assay creator: Ziva Ramsak Phenodata: None Featuredata: Data:
Submitter: Maja Zagorscak
Biological problem addressed: Annotation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /intermediate_4_cdhit-2d.tar.gz, /output/output.tar, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_03.1_filtering Short Name: 03.1_filtering Assay Class: DRY Assay Type: filtering Title: Filtering according to biological evidence; removal of contaminants, chimeras and suspicious constructs Description: Filtering according to biological evidence; removal of contaminants, chimeras and suspicious constructs pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: No organisms
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /intermediate/intermediate.tar, /output/Desiree_tr.cds.tsv.gz, /output/PW363_tr.cds.tsv.gz, /output/Rywal_tr.cds.tsv.gz, /output/other/output_full.tar.gz, /output/other/output_summary.tar.gz, /reports/03.1_Rywal_combo_withFiltering.html, /reports/03.2_PW363_combo_withFiltering.html, /reports/03.3_Desiree_combo_withFiltering.html, /reports/SupplementaryTableS3, /reports/SupplementaryTableS4, /reports/SupplementaryTableS5, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_02.8_DIAMOND Short Name: 02.8_DIAMOND Assay Class: DRY Assay Type: DIAMOND Title: DIAMOND on raw tr2aacds output Description: DIAMOND on raw tr2aacds output, both .cds and .tr; including lost and found pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Annotation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /output/output.tar, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_02.7_VecScreen Short Name: 02.7_VecScreen Assay Class: DRY Assay Type: VecScreen Title: VecScreen on raw tr2aacds output Description: VecScreen (contamination screening) and blastn (contaminants annotation) on raw (initial) tr2aacds output pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum, Potato virus Y
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /intermediate.tar.gz, /output/Desiree_vecscreen.tsv, /output/PW363_vecscreen.tsv, /output/Rywal_vecscreen.tsv, /scripts/01_get_input.sh, /scripts/02_VecScreenPlus_blastn.sh, /scripts/ENCH_sumablastplus.pl
Snapshots: Snapshot 1
Assay: _A_02.6_TransRate Short Name: 02.6_TransRate Assay Class: DRY Assay Type: TransRate Title: TransRate stat on raw tr2aacds transcriptomes Description: TransRate stat on raw (initial) tr2aacds transcriptomes, basic and reference-based pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: Nonde Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /output/output.tar, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_02.5_STARlong_matchAnnot Short Name: 02.5_STARlong_matchAnnot Assay Class: DRY Assay Type: matchAnnot Title: potato transcriptome v2 (evigene) STARlong mapping of transcripts to reference genome and MatchAnnot to get transcript annotations Description: potato initial transcriptome (evigene) STARlong mapping of transcripts to reference genome and MatchAnnot to get transcript annotations pISA Assay creation date: 2019-10-22 pISA Assay creator: Marko Petek Phenodata: None Featuredata: None ...
Submitter: Maja Zagorscak
Biological problem addressed: Annotation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /output/output_1_STARlong-logs-n-SJ.tar.gz, /output/output_2_matchAnnot-parsed-txt.tar.gz, /scripts/STARlongMatchAnnot_commands_ENCODE_den...
Snapshots: Snapshot 1
Assay: _A_02.4_STAR Short Name: 02.4_STAR Assay Class: DRY Assay Type: STAR Title: mapping reads back to evigene .tr output Description: mapping reads back to evigene .tr output using STAR to check the percentage of reads that map pISA Assay creation date: 2019-10-22 pISA Assay creator: Marko Petek Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /output/output_STAR_logs-n-SJ.tar.gz, /output/samtoolsCoverage.zip, /reports/summaryCounts&SJ.xlsx, /scripts/STAR_commands.txt
Snapshots: Snapshot 1
Assay: _A_02.3_InterProScan Short Name: 02.3_InterProScan Assay Class: DRY Assay Type: InterProScan Title: InterProScan on tr2aacds output Description: InterProScan on tr2aacds output pISA Assay creation date: 2019-10-22 pISA Assay creator: Marko Petek Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Annotation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /intermediate/intermediate.tar, /output/Desiree_IPS_filtered_aggregated_filtere..., /output/PW363_IPS_filtered_aggregated_filtered.tsv, /output/Rywal_IPS_filtered_aggregated_filtered.tsv, /reports/IPS_PowerQuery_PivotTable.xlsx, /scripts/01_potato_tr_evigene_IPS_commands.txt, /scripts/02_reshape_merge_aggregate_filter.Rmd
Snapshots: Snapshot 1
Assay: _A_02.2_assembly-contribution-count Short Name: 02.2_assembly-contribution-count Assay Class: DRY Assay Type: count Title: assembly contribution count Description: assembly contribution count, input/output tr2aacds pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Model Analysis Type
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /intermediate_Desiree.tar.gz, /intermediate_PW363.tar.gz, /intermediate_Rywal.tar.gz, /output/output.tar, /reports/SupplementaryFigure1.pdf, /reports/SupplementaryFigure2.pdf, /reports/SupplementaryFigure3.pdf, /reports/SupplementaryTableS6, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_02.1_BUSCO Short Name: 02.1_BUSCO Assay Class: DRY Assay Type: BUSCO Title: BUSCO on assemblies and tr2aacds output Description: BUSCO on assemblies and tr2aacds output pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Validation
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum
Models: No Models
SOPs: No SOPs
Data files: /input/input.tar, /output/output.tar, /scripts/scripts.tar
Snapshots: Snapshot 1
Assay: _A_01_evigene Short Name: 01_evigene Assay Class: DRY Assay Type: evigene Title: EvidentialGene tr2aacds.pl VERSION 2016.07.11 Description: See http://eugenes.org/EvidentialGene/about/EvidentialGene_trassembly_pipe.html pISA Assay creation date: 2019-10-22 pISA Assay creator: Maja Zagorscak Phenodata: None Featuredata: None Data: see ./input/path_to_files.txt
Submitter: Maja Zagorscak
Biological problem addressed: Integration
Investigation: _I_STRT
Study: _S_03_stCuSTr
Organisms: Solanum tuberosum, Potato virus Y
Models: No Models
SOPs: No SOPs
Data files: /input/path_to_files.txt, /intermediate_tr2aacds_Desiree.tar.gz, /intermediate_tr2aacds_PW363.tar.gz.aa, /intermediate_tr2aacds_PW363.tar.gz.ab, /intermediate_tr2aacds_Rywal.tar.gz, /output/output.tar, /scripts/01_run_commands.sh, /scripts/my_tr2aacds.sh, /scripts/run_tr2aacds.sh
Snapshots: Snapshot 1
1 file with legends 4 files with figures 2 files with tables
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
First version of Genome-scale metabolic model (GEM) for reconstraction of flavonoids biosynthetic pathways. This model includes as a chassis , the Pseudomonas Putida GEM (iJN1411) . It includes the metabolic reconstruction of more than 500 flavonoids and more than 500 reactions related to the flavonoid biosynthesis.
Creators: David San León Granado, Juan Nogales, Álvaro Gargantilla Becerra
Submitter: David San León Granado
Model type: Metabolic network
Model format: SBML
Environment: Matlab
Organism: Pseudomonas putida
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Model that can be used to obtain the figures of Abudulikemu et al 2018: Abudukelimu, A., Barberis, M., Redegeld, F.A., Sahin, N., and Westerhoff, H.V. (2018). Predictable Irreversible Switching Between Acute and Chronic Inflammation. Front Immunol 9, 1596.
Creators: Hans V. Westerhoff, Ablikim Abudukelimu
Submitter: Hans V. Westerhoff
Model type: Ordinary differential equations (ODE)
Model format: Copasi
Environment: Copasi
Organism: Not specified
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The model presents a multi-compartmental (mesophyll, phloem and root) metabolic model of growing Arabidopsis thaliana. The flux balance analysis (FBA) of the model quantifies: sugar metabolism, central carbon and nitrogen metabolism, energy and redox metabolism, proton turnover, sucrose translocation from mesophyll to root and biomass growth under both dark- and light-growth conditions with corresponding growth either on starch (in darkness) or on CO2 (under light). The FBA predicts that ...
Creators: Maksim Zakhartsev, Olga Krebs, Irina Medvedeva, Ilya Akberdin, Yuriy Orlov
Submitter: Maksim Zakhartsev
Model type: Metabolic network
Model format: SBML
Environment: Not specified
Organism: Arabidopsis thaliana
Investigations: Metabolic analysis of effects of sucrose transl... and 1 hidden item
Studies: Analysis of central carbon and energy metabolis... and 1 hidden item
Assays: Flux Balance Analysis of multi-compartment meta... and 1 hidden item
Abstract (Expand)
Authors: Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch, Uta Dahmen
Date Published: 1st Dec 2022
Publication Type: Journal
DOI: 10.1038/s41598-022-26483-6
Citation: Sci Rep 12(1),21825
Abstract (Expand)
Authors: Yin Hoon Chew, Daniel D Seaton, Virginie Mengin, Anna Flis, Sam T Mugford, Gavin M George, Michael Moulin, Alastair Hume, Samuel C Zeeman, Teresa B Fitzpatrick, Alison M Smith, Mark Stitt, Andrew J Millar
Date Published: 1st Jul 2022
Publication Type: Journal
DOI: 10.1093/insilicoplants/diac010
Citation: in silico Plants 4(2),diac010
Abstract (Expand)
Authors: Mitsuhiro Odaka, Morgan Magnin, Katsumi Inoue
Date Published: 11th Feb 2022
Publication Type: Journal
DOI: 10.21203/rs.3.rs-1300133/v1
Citation: [Preprint]
Abstract (Expand)
Authors: Uriel Urquiza Garcia, Andrew J Millar
Date Published: 5th Aug 2021
Publication Type: Journal
DOI: 10.1093/insilicoplants/diab022
Citation:
Abstract (Expand)
Authors: Chris J. Myers, Gary Bader, Padraig Gleeson, Martin Golebiewski, Michael Hucka, Nicolas Le Novere, David P. Nickerson, Falk Schreiber, Dagmar Waltemath
Date Published: 1st Dec 2017
Publication Type: InProceedings
Citation: 2017 Winter Simulation Conference (WSC),pp.884-895,IEEE
Abstract (Expand)
Authors: Maxwell Lewis Neal, Matthias König, David Nickerson, Göksel Mısırlı, Reza Kalbasi, Andreas Dräger, Koray Atalag, Vijayalakshmi Chelliah, Michael T Cooling, Daniel L Cook, Sharon Crook, Miguel de Alba, Samuel H Friedman, Alan Garny, John H Gennari, Padraig Gleeson, Martin Golebiewski, Michael Hucka, Nick Juty, Chris Myers, Brett G Olivier, Herbert M Sauro, Martin Scharm, Jacky L Snoep, Vasundra Touré, Anil Wipat, Olaf Wolkenhauer, Dagmar Waltemath
Date Published: 1st Mar 2019
Publication Type: Journal
DOI: 10.1093/bib/bby087
Citation: Briefings in Bioinformatics 20(2):540-550
Abstract (Expand)
Author: Martin Golebiewski
Date Published: 2019
Publication Type: InBook
DOI: 10.1016/B978-0-12-809633-8.20471-8
Citation: Encyclopedia of Bioinformatics and Computational Biology,pp.884-893,Elsevier
Abstract (Expand)
Authors: Falk Schreiber, Björn Sommer, Gary D. Bader, Padraig Gleeson, Martin Golebiewski, Michael Hucka, Sarah M. Keating, Matthias König, Chris Myers, David Nickerson, Dagmar Waltemath
Date Published: 13th Jul 2019
Publication Type: Journal
Citation: Journal of Integrative Bioinformatics 16(2)
Abstract (Expand)
Authors: Alexey Kolodkin, Raju Prasad Sharma, Anna Maria Colangelo, Andrew Ignatenko, Francesca Martorana, Danyel Jennen, Jacco J. Briede, Nathan Brady, Matteo Barberis, Thierry D.G.A. Mondeel, Michele Papa, Vikas Kumar, Bernhard Peters, Alexander Skupin, Lilia Alberghina, Rudi Balling, Hans V. Westerhoff
Date Published: No date defined
Publication Type: Not specified
DOI: 10.1101/647776
Citation: Design principles of ROS dynamic networks relevant to precision therapies for age-related diseases 74 : 324
Abstract (Expand)
Authors: Marko Petek, Maja Zagorščak, Živa Ramšak, Sheri Sanders, Elizabeth Tseng, Mohamed Zouine, Anna Coll, Kristina Gruden
Date Published: No date defined
Publication Type: Not specified
DOI: 10.1101/845818
Citation: Cultivar-specific transcriptome and pan-transcriptome reconstruction of tetraploid potato
Abstract (Expand)
Authors: K. van Eunen, C. M. Volker-Touw, A. Gerding, A. Bleeker, J. C. Wolters, W. J. van Rijt, A. M. Martines, K. E. Niezen-Koning, R. M. Heiner, H. Permentier, A. K. Groen, D. J. Reijngoud, T. G. Derks, B. M. Bakker
Date Published: 7th Dec 2016
Publication Type: Journal
PubMed ID: 27927213
Citation: BMC Biol. 2016 Dec 7;14(1):107. doi: 10.1186/s12915-016-0327-5.
Abstract
Editor:
Date Published: 24th Oct 2017
Publication Type: Not specified
Citation: Knopp C. Nutzung von Persistent Identifiern zur Umsetzung der FAIR-Prinzipien in Datenablageplattformen für die medizinische Forschung [Bachelorarbeit]. Göttingen: Georg-August-Universität; 2017.
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Authors: Yin Hoon Chew, Daniel D. Seaton, Virginie Mengin, Anna Flis, Sam T. Mugford, Alison M. Smith, Mark Stitt, Andrew J Millar
Date Published: 6th Feb 2017
Publication Type: Tech report
DOI: 10.1101/105437
Citation: biorxiv;105437v1,[Preprint]
Abstract (Expand)
Authors: F. Schreiber, G. D. Bader, P. Gleeson, M. Golebiewski, M. Hucka, N. Le Novere, C. Myers, D. Nickerson, B. Sommer, D. Walthemath
Date Published: 12th Feb 2017
Publication Type: Not specified
PubMed ID: 28187405
Citation: J Integr Bioinform. 2016 Dec 18;13(3):289. doi: 10.2390/biecoll-jib-2016-289.
FAIR Data, Operations and Model management for Systems Biology and Systems Medicine Projects given at 1st Conference of the European Association of Systems Medicine, 26-28 October 2016, Berlin. the FAIRDOM project is described.
Creator: Carole Goble
Submitter: Carole Goble
Lecture 2: Being Reproducible: Models, Research Objects and R* Brouhaha Reproducibility is a R* minefield, depending on whether you are testing for robustness (rerun), defence (repeat), certification (replicate), comparison (reproduce) or transferring between researchers (reuse). Different forms of "R" make different demands on the completeness, depth and portability of research. Sharing is another minefield raising concerns of credit and protection from sharp practices. In practice the exchange, ...
Creator: Carole Goble
Submitter: Carole Goble
Presented at Digital Life 2018, Bergen, March 2018. In the Trust and Accountability session. In recent years we have seen a change in expectations for the management and availability of all the outcomes of research (models, data, SOPs, software etc) and for greater transparency and reproduciblity in the method of research. The “FAIR” (Findable, Accessible, Interoperable, Reusable) Guiding Principles for stewardship [1] have proved to be an effective rallying-cry for community groups and for policy ...
Creator: Carole Goble
Submitter: Carole Goble
A personal view of the big picture in Research Data Management, given at GFBio - de.NBI Summer School 2018 Riding the Data Life Cycle! Braunschweig Integrated Centre of Systems Biology (BRICS), 03 - 07 September 2018
Creator: Carole Goble
Submitter: Carole Goble
FAIRDOM User Meeting, Lyon, France, 27 Oct 2018 Introduction to FAIRDOM Project and platforms
Creators: Carole Goble, Natalie Stanford
Submitter: Carole Goble
COMBINE 2019, EU-STANDS4PM, Heidelberg, Germany 18 July 2019 FAIR: Findable Accessable Interoperable Reusable. The “FAIR Principles” for research data, software, computational workflows, scripts, or any other kind of Research Object one can think of, is now a mantra; a method; a meme; a myth; a mystery. FAIR is about supporting and tracking the flow and availability of data across research organisations and the portability and sustainability of processing methods to enable transparent and ...
Creator: Carole Goble
Submitter: Carole Goble
Introductory talk given by Olga Krebs in the Department of Chemical Engineering at the University of Rovira i Virgili on 19th of July 2017
Creator: Olga Krebs
Submitter: Olga Krebs
Introductory talk given by Olga Krebs in the Department of Chemical Engineering at the University of Rovira i Virgili on 19th of July 2017
Creator: Olga Krebs
Submitter: Olga Krebs
Talk given by Olga Krebs at EmPowerPutida project meeting in Bruxeles 23rd November 2016
Creators: Olga Krebs, Carole Goble, Rostyslav Kuzyakiv, Wolfgang Müller, Quyen Nguyen, Stuart Owen, Bernd Rinn, Jacky Snoep, Natalie Stanford
Submitter: Olga Krebs
Written and presented by Mihai Glont (EMBL-EBI, UK), at the Reproducible and Citable Data and Model Workshop, September 14th -16th 2015.
Creators: Natalie Stanford, Mihai Glont (EMBL-EBI, UK)
Submitter: Natalie Stanford
The Minimum Information about a Molecular Interaction Causal Statement to guide the curation of causal statements.
Creator: Vasundra Toure
Submitter: Vasundra Toure
Investigations: WP1: Creation of an integrated and curated canc...
Studies: Deliverable 1.1: Draft curation guidelines for ...
Assays: MI2CAST curation guidelines
Creators: Lutz Brusch, Jörn Starruß
Submitter: Lutz Brusch
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Lutz Brusch, Jochen Kursawe, Jörn Starruß
Submitter: Lutz Brusch
Investigations: No Investigations
Studies: No Studies
Assays: No Assays