Institutions: University of Freiburghttps://orcid.org/0000-0002-5340-3423
Institutions: University Maastrichthttps://orcid.org/0000-0002-5301-3142
Institutions: University of Bergenhttps://orcid.org/0000-0002-2484-9047
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Genetics, Genomics, R, Systems Biology, Transcriptomics, Java
My scientific interests revolve around functional genomics, systems biology and the development of algorithms and software for the analysis of high-throughput data (mainly, but not restricted to, Next Generation Sequencing) and its application to the relationship between genotype and phenotype, mainly oriented to personalized and precision medicine. I am especially interested in the study of disease mechanisms and drug action mechanisms, drug repositioning and the definition of mechanism-based ...
Expertise: Genetics, Molecular Biology, Microarray analysis, Bacillus subtilis, phenotypic heterogeneity, gene regulation, stress responses, protein secretion, functional protein expression, microscopy, fluorescence protein fusions (transcriptional and translational), localisation studies
Tools: Genetic modification, Transcriptomics, Microarray analysis, Fluorecence based reporter gene analyses/single cell analyses, Site-directed mutagenesis, Fluorescence microscopy, Flow cytometry, Immunofluorescence, transposon mutagenesis, Molecular biology techniques (RNA/DNA/Protein), DNA affinity chromatography, EMSA
PhD student. Analyzing CcpA affinity to cre boxes (catabolite responsive elements) and response of B. subtilis to membrane protein overproduction stress.
Senior Research Scientist at SINTEF, Dept. of Biotechnology and Nanomedicine, Research Group Mass Spectrometry
Research fellow in Bioinformatics at the Warwick Systems Biology Centre, University of Warwick.
Working on high throughput data analysis (microarray data, next generation sequencing) and data integration (database management, text-mining, gene annotation via public databases)...