Assays

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583 Assays visible to you, out of a total of 1118

Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD+ in medium-chain acyl-CoA dehydrogenase knockout mice. Expression profiling by high throughput sequencing

Submitter: PoLiMeR_user Martines_data

Assay type: Transcriptomics

Technology type: Rna-seq

Snapshots: No snapshots

Motivated by an increasing population and the desire to grow plants more efficiently,
attention has turned to the use of Light Emitting Diodes (LEDs) to illuminate plants
which are grown indoors. Indoor growing facilities enable closely controlled and mon-
itored environmental conditions. More and more of these facilities exchange High
Pressure Sodium (HPS) lamps for LED lighting since they provide more efficient
lighting and the possibility to control light intensity and quality in order to
...

Submitter: Felix Steimle

Assay type: Experimental Assay Type

Technology type: Chlorophyll Fluorescence Analysis

Snapshots: No snapshots

Differential expression analysis (using R package edgeR) on liver gene expression between salmon with all four fads2 genes knockout, only fads2d6b & fads2d6c knockout and wildtype. All salmon was given either a low-PUFA diet or a high-PUFA diet

Submitter: Yang Jin

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

No description specified

Submitter: Yang Jin

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Here, we conduct a proof of principle by comparing a 2D and 3D fluorescent image analysis based approach on unlabeled cardiomyocytes. Based on the CellProfiler software, we extracted high-dimensional features of individual cells and nuclei, which are subsequently down-sampled and clustered. These clusters are furthermore benchmarked via different machine learning classifiers (e.g., AdaBoost, Gradient Boosting, Random Forest) as the ground truth for our proposed approach.

Submitter: Markus Wolfien

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

Docking results of pteridine-based compounds in different target PTR1 and DHFR receptors and the off-target human DHFR when using an induced fit docking routine with an initial crude ligand placement step, subsequent receptor optimization in response to ligand binding and another docking step into the optimized receptor.

Computational prediction of physicochemical and advanced descriptors related to ADME-Tox.

Assessment of possible linear correlations between predicted ADMET descriptors from QikProp (Schrödinger, LLC, New York, NY) runs and experimentally determined activities against T. brucei brucei bloodstream forms with the help of a Python script.

Submitter: Ina Poehner

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

Assessment of the possible multiple correlation between experimentally determined TbPTR1 and TbDHFR inhibition values and corresponding anti-parasitic activities against T. brucei brucei bloodstream forms using a Python script.

Submitter: Ina Poehner

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

In silico check and filtering for potential Pan-assay interference compounds.

Submitter: Ina Poehner

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

Compound data, library construction schemes and preparation routine for small drug-like molecules as ligands in docking and for further analysis.

Model files for FMv1.5. The model is based on FMv1 of Chew et al. PNAS 2014, which is also in FAIRDOMHub and linked to the Model record as an 'Attribution'. FMv1 was extended in this work by Hannah Kinmonth-Schultz and Daniel Seaton, in Matlab.

Submitter: Andrew Millar

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

No description specified

Submitter: Gudrun Gygli

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

To obtain each of the figure 4A - 4D please download "Main Figure 4 Copasi" and open the sub-directory with the name of the sub-figure, run the Copasi files and the time dependence simulation. This will reproduce the figure in this paper.

Submitter: Alexey Kolodkin

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

To obtain each of the figure 2A - 2E please download "Main Figure Copasi" and open the sub-directory with the name of the sub-figure, run the Copasi files and the time dependence simulation. This will reproduce the figure in this paper.

Submitter: Alexey Kolodkin

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

No description specified

Submitter: Alexey Kolodkin

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

No description specified

Submitter: Alexey Kolodkin

Biological problem addressed: Model Analysis Type

Snapshots: No snapshots

Results from lipidomics analyses performed in cod liver microsomes of cod exposed to PAH and PFAS mixtures.

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Some results from proteomics analyses of cod liver exposed to PAH and PFAS

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Concentration of the egg yolk precursor protein vitellogenin in cod plasma

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Gene expression of cyp1a and acox1 measured by qPCR in liver of Atlantic cod exposed to PAHs and PFASs

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Semi-quantitative determination of Cyp1a protein amount in cod liver, using the ELISA method.

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Measurement of DNA fragmentation using the Comet Assay, in white blood cells of Atlantic cod exposed to PAHs and PFASs

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

Measurements of PAH metabolites in bile (1-OH-napthalene, 2-OH-naphthalene, 1-OH-phenanthrene, 1-OH-pyrene) and PFAS compounds in liver (PFOS, PFOA, PFNA, PFTrDa)
in Atlantic cod exposed to mixtures of PAHs and PFASs.

Submitter: Karina Dale

Assay type: Experimental Assay Type

Technology type: Technology Type

Snapshots: No snapshots

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