Projects

A collection of basic data for subjects that may be eligible to one or more research projects.

Here you can find some Raman data.

Development of a lactic acid centred biorefinery scheme to valorize flexibly organic waste streams into biochemicals

The group around Nicole Radde specializes in the modeling, analysis, and simulation of biochemical systems. This especially includes parameter optimization and identification.

3T3 murine embryonic fibroblasts are used as feeder layers to support the proliferative potential of human primary keratinocytes during in vitro expansion for cell and gene therapy applications. To identify signals mediating this function, we analyzed fibroblast protein content using mass spectrometry. We compared the proteome of lethally irradiated fibroblasts used as feeder layers at two time points: 24 hours and 4 days post-seeding. Our findings highlight differences in extracellular matrix ...

The New Medicines for Trypanosomatidic Infections - NMTrypI project aimed at obtaining new candidate drugs against Trypanosomatidic infections with appropriate efficiency from the lead phase to the final preclinical phase that are more accessible to patients.

The mission of the Virtual Human Platform is to improve the prediction of the potential harmful effects of chemicals and pharmaceuticals based on a holistic, interdisciplinary definition of human health by developing the Virtual Human Platform and accelerating the transition from animal-based testing to innovative safety assessment. The Virtual Human Platform integrates data on human physiology, chemical characteristics and perturbations of biological pathways, for the first time in an inclusive ...

HCM protocols from TEATIME members

Background: The immunoproteasome is expressed constitutively in immune cells alongside standard proteasomes and forms multiple mixed types of proteasome complexes. These mixed 20S proteasomes may have distinct proteolytic activities depending on their subunit composition and may thereby regulate immune cell function. Using site-specific versus pan-inhibitors of the immunoproteasome, we here aim to dissect the biological functions of the three active sites of the immunoproteasome for monocyte cell ...

The Academic Scientific Research Group is an organization dedicated to organizing both international and local scientific-practical conferences. Their official website, asr-conference.com, provides detailed information about upcoming events, submission guidelines, and other relevant resources.One of their notable events is the upcoming scientific-practical conference titled "The National-Social Significance of Music Education and Art in Today's Globalization Context: Issues and Solutions," scheduled ...

About

This project houses all the publicly available datasets generated by the Hi-IMPAcTB consortium over the course of its 7+ years.

What is Hi-IMPAcTB?

Hi-IMPAcTB is an ambitious endeavor bringing together a team of international, interdisciplinary researchers to improve our understanding of host-pathogen interactions in the context of tuberculosis (TB). Funded by a multi-center contract from the NIH, the long-term goal of the consortium is to enable principled vaccine design by improving ...

Aliivibrio Vl2 vs. Moritella viscosa

Vl2 vs M. viscosa

This is only a test

A fundamental and enduring challenge for ecosystem managers developing risk and impact assessment tools is to predict the extent of impact that spilled oil can have on the immediate fish populations and on future generations. Modelling approaches are important tools for these assessments, but they currently suffer from two major shortcomings: 1) the failure to acknowledge that effects can be transferred through several generations and 2) the assumption that a small group of toxic compounds, ...

This study investigated whether potentially harmful microorganisms from research laboratories and biotechnology companies can survive in nearby water systems. It focused on three Dutch cities - Leiden, Delft, and Alphen aan den Rijn - and collected water samples between May and September 2024.

The current project is created as a potential repository for resources resulting from the Virtual Human Platform for Safety Assessment (VHP4Safety) project.

A healthy lifestyle is the basis for adequate management in cardiovascular and other chronic conditions. The BENEFIT program aims to provide long-term support to patients with cardiovascular disease (CVD) in their own home with a healthy lifestyle.The FAIR Data approach in BENEFIT standardises and structures the data collected in the project, for better use and reuse. This metadata record describes the data available and provides a contact point for researchers who would like to apply to use the ...

This project collects and maintains minimum information metadata templates designed and used in the National NL-Bioimaging initiative. The templates are based on the REMBI standards and contribute to FAIR bioimaging data in the Netherlands, together with data management in the OMERO database.