Projects

Investigation of the regulation of different phosphoglucomutase variants from Synechocystis

Model-based design of a biorefinery platform to valorise agrifood organic waste into odd-chain volatile fatty acids integrating technical and environmental criteria

The conversion of organic wastes by anaerobic fermentation (the so-called carboxylate platform) is one of the promising emerging biorefineries that allows valorising organic carbon to volatile fatty acids (VFA), which can be further processed as chemicals, biopolymers and biofuels. A major obstacle to the widespread of the carboxylate ...

A healthy lifestyle is the basis for adequate management in cardiovascular and other chronic conditions. The BENEFIT program aims to provide long-term support to patients with cardiovascular disease (CVD) in their own home with a healthy lifestyle.The FAIR Data approach in BENEFIT standardises and structures the data collected in the project, for better use and reuse. This metadata record describes the data available and provides a contact point for researchers who would like to apply to use the ...

Good data and model management improves the longevity and impact of your interdisciplinary research. FAIRDOM offers software and expertise to support you in better managing your interdisciplinary life-science projects, particularly in systems and synthetic biology. If you have never heard of data and model management, or are curious about it, or you are an expert keen to exchange ideas, our user meeting is the place for you!

At our users meeting you can:

• Learn why data and model management is ...

AgriVoltaics World Conference 2024 - Presentation manuscript data upload.

The group around Nicole Radde specializes in the modeling, analysis, and simulation of biochemical systems. This especially includes parameter optimization and identification.

About

This project houses all the publicly available datasets generated by the Hi-IMPAcTB consortium over the course of its 7+ years.

What is Hi-IMPAcTB?

Hi-IMPAcTB is an ambitious endeavor bringing together a team of international, interdisciplinary researchers to improve our understanding of host-pathogen interactions in the context of tuberculosis (TB). Funded by a multi-center contract from the NIH, the long-term goal of the consortium is to enable principled vaccine design by improving ...

Real-time smart monitoring of bioprocesses for efficient conversion of organic carbon to volatile fatty acids

Background: The immunoproteasome is expressed constitutively in immune cells alongside standard proteasomes and forms multiple mixed types of proteasome complexes. These mixed 20S proteasomes may have distinct proteolytic activities depending on their subunit composition and may thereby regulate immune cell function. Using site-specific versus pan-inhibitors of the immunoproteasome, we here aim to dissect the biological functions of the three active sites of the immunoproteasome for monocyte cell ...

Engineering next level photosynthesis-PhotoBoost is a 4-year research and innovation action that aims to significantly improve the efficiency of photosynthesis in plants. The optimisation of photosynthesis will be achieved by capitalising on multidisciplinary approaches including computational biology, metabolic modelling, systems biology, enzyme and pathway engineering, synthetic biology, and the multigene transformation of two major C3 crops: potato and rice. The PhotoBoost project will deliver ...

A wide variety of specimen types may be collected for storage, depending on availability and study goals, such as tissues that from autopsy and transplant, cell lines, and so on.Timing. In general, it is important to minimize the time between collection and stabilization and processing of tissue specimens. This time will vary according to the intended use, since different biomolecules degrade at different rates. The effects of collection timing on tissue and macromolecule preservation have not ...

FAIRDOM will establish a support and service network for European Systems Biology. We will serve projects in standardising, managing and disseminating data and models in a FAIR manner: Findable, Accessible, Interoperable and Reusable.

Mission: We perform cutting-edge research on data generated by novel biomolecular technologies to address questions in pneumology. Towards this, we use biological high-throughput data, i.e., OMICs data, to gain insights into molecular and phenotypic traits and diseases using computational methods. We combine data, methodology and their applications in pneumology through interdisciplinary collaboration with mathematicians, computer scientists, biologists and physicians.

Collection of training material for SEEK/FAIRDOMHub

Following the user guide

Objective: Identify specific brain regions and cell types that are more susceptible to neurodegenerative diseases, using the high-resolution atlas of cell types to determine the molecular signatures associated with disease vulnerability.