Projects

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236 Projects found

ORHIZON-FAIR IS A HORIZON EUROPE PROJECT AIMED AT DELIVERING SOLUTIONS FOR ROOT AND RHIZOSPHERE TRAITS BASED BREEDING IN THE CONTEXT OF LOW INPUT AGRICULTURE AND CLIMAT CHANGE

Programme: Independent Projects

Public web page: Not specified

Here we share resources and best practices to develop a disease map for COVID-19. The project is progressing as a broad community-driven effort. We aim to establish a knowledge repository on virus-host interaction mechanisms specific to the SARS-CoV-2. The COVID-19 Disease Map is an assembly of molecular interaction diagrams established based on literature evidence.

genetical innovation

Programme: Independent Projects

Public web page: Not specified

FAIRDOM will establish a support and service network for European Systems Biology. We will serve projects in standardising, managing and disseminating data and models in a FAIR manner: Findable, Accessible, Interoperable and Reusable.

Programme: FAIRDOM

Public web page: http://fair-dom.org/

Start date: 1st Nov 2014

Microalgae Microbiomes: A natural source for the prevention and treatment of diseases in aquaculture

Aquaculture is one of the fastest growing food sectors in the world. In order to guarantee continuous, efficient and sustainable production and to safeguard the growth of this important sector, its protection from biological threats is crucial. Within the AquaHealth project, an international consortium of highly experienced partners will assemble and apply an advanced meta’omics toolbox on the ...

Programme: BlueBio ERA-NET COFUND

Public web page: https://aquahealth-project.com/

Start date: 1st May 2020

End date: 30th Apr 2023

Cyanobacteria are the only prokaryotes performing oxygenic photosynthesis. Theyhad and have tremendous influence on the biogeochemical cycles on Earth. Recently,cyanobacteria are increasingly investigated as cell factories for a sustainableeconomy. Despite their global, environmental and rising economic importance, ourknowledge on the regulation of their primary metabolism is fragmented.Cyanobacteria switch between photoautotrophic and heterotrophic modes ofmetabolism during day/night cycles or ...

Programme: DFG founded projects

Public web page: https://gepris.dfg.de/gepris/projekt/397695561

Start date: 1st Sep 2018

nfdi4health aims to create the most comprehensive inventory of German epidemiological, public health and clinical trial data to date. It builds a centralised data catalogue with elaborate search functionalities, sophisticated data access management, and a data analysis toolbox, while respecting stringent requirements for privacy concerning personal health data. Standardisation services ensure a high degree of interoperability. Use cases covering prototypical study types and areas of research show ...

CLIMAQUA results in an innovative process for converting and recirculating aquaculture side-streams (sludge and wastewater) in algae (Arthrospira platensis)-based feed production for aquacultures. In conventional aquaculture, feed production is responsible for 50% of greenhouse gas (GHG) emission. The aim is to substantially reduce GHG emission by considering geographic and site-specific characteristics (temperature, sunshine duration etc.) and to design site-specific phototrophic or heterotrophic ...

Programme: CLIMAQUA

Public web page: https://www.foscera.net/en/foscera/Projects/CLIMAQUA.htm

Start date: 1st Jun 2021

End date: 31st May 2024

The project brings comprehensive study of diversity in Clostridium beijerinckii, solvent-producing species with potential use in industrial biotechnology.

Programme: Clostridium beijerinckii

Public web page: Not specified

Collection of training material for SEEK/FAIRDOMHub

Programme: FAIRDOM

Public web page: Not specified

The project addresses the generation and establishment of programmed pacemaker cells for an in vitro drug testing possibility to perform predictive tests. This may lead to an improved treatment of cardiac arrhythmias or an accurate identification of potential drug molecules at a very early stage of development. Important benefits will arise in verifying the safety of a wide variety of medicines while reducing animal testing. For more information you may visit our project website at ...

No description specified

Programme: Testing 1, 2, 3

Public web page: Not specified

An experimental workflow to provide detailed information of the molecular mechanisms of enzymes is described. This workflow will help in the application of enzymes in technical processes by providing crucial parameters needed to plan, model and implement biocatalytic processes more efficiently. These parameters are homogeneity of the enzyme sample (HES), kinetic and thermodynamic parameters of enzyme kinetics and binding of reactants to enzymes. The techniques used to measure these properties are ...

Programme: Gygli Group

Public web page: Not specified

Start date: 1st Nov 2019

No description specified

Programme: Supplemental Data for "Why did the eyewall replacement cycle in Trami terminate rapidly? "

Public web page: Not specified

Start date: 29th Apr 2021

End date: 31st Aug 2021

No description specified

Programme: Cancer drug discovery preclinical research

Public web page: Not specified

No description specified

Programme: Gygli Group

Public web page: Not specified

Start date: 1st Nov 2019

The Hippo signalling is a metabolic control pathway of cells proliferation and apoptosis, thus represents an emerging topic in tumour suppression regulation and regenerative medicine. This pathway is activated by anti-proliferative signals which come from the extracellular environment received by membranes proteins. In the cytosol compartment, the pathway is regulated by a phosphorylation cascade of four main proteins with Serin-Treonin kinase activity. At the end-point of this cascade the ...

Programme: Cancer drug discovery preclinical research

Public web page: Not specified

From thermodynamics through kinetics and non equilibrium thermodynamics to control analysis

Programme: Thermodynamics and kinetics for Biology

Public web page: http://sysba.nl/

Start date: 8th Apr 2021

End date: 8th Apr 2031

Chapter on non equilibrium thermodynamics. The chapter discusses both phenomenological and mechanistic non equilibrium thermodynamics. The phenomenological part has as asset compared to earlier treatments that it also considers the phenomenological stoichiometry as a parameter that may be adjusted by systems to attain optimal performance. In the mechanistic part, this feature of variable stoichiometry and 'slips' as well as redistribution of fluxes over parallel branches of metabolism is discussed. ...

Programme: Thermodynamics and kinetics for Biology

Public web page: http://sysba.nl/

Start date: 8th Apr 2021

End date: 8th Apr 2031

A chapter on generalized thermodynamics. The chapter is not specifically about biology although it uses many examples in biology due to the richness of the topic. It deals with the first and second law of thermodynamics, catalysts, and engines. This includes heat engines, heat pumps, and protonmotive ATP synthase.

Programme: Thermodynamics and kinetics for Biology

Public web page: http://sysba.nl/

Start date: 8th Apr 2021

End date: 8th Apr 2031

Most systems biology deals with Life as we know it on this planet (Earth). This project will focus on how (nonsynthetic) Life may differ from mainstream Life. The ultimate focus thereby rests on extraterrestrial Life, but for lack of definitive evidence of this, the project studies Life found under conditions that may be similar to extraterrestrial conditions enabling Life. The focus is herewith on the systems biology in remote environments on Earth. The project deals both with the systems cell ...

Programme: ISBE.NL service programme

Public web page: http://isbe.nl/

Start date: 8th Apr 2021

End date: 8th Apr 2025

This is the FAIRDOM hub for the Make Me My Model part of ISBE.NL. Various models for ISDBE.NL clients are stored here.

Programme: Innate immunity

Public web page: http://isbe.nl/

Systems Biology as we know it is mostly terrestrial, i.e. it deals with mainstream Life on planet Earth. There are two exceptions. One is synthetic systems biology that designs other types of Life. The other exception studies the systems that may exist on other planets, or that exists at remote locations on planet Earth. Xenosystems Biology refers to the latter exception. At present this runs projects that deal with Life as found at remote locations on Earth, which are held representative of other ...

Programme: Innate immunity

Public web page: http://isbe.nl/

Start date: 8th Apr 2021

End date: 8th Apr 2031

CEPOPA envisions a sustainable cascade one-pot process for the synthesis of optically pure amines from alcohols and/or alkynes, using enzymes immobilized onto catalytically active nanomaterials. In the framework of the project, efficient chemoenzymatic processes will be developed for the synthesis of a set of amines that can be used as building blocks for pharmaceuticals or biomaterials.

Programme: Hellenic Foundation for Research and Innovation - Supporting academic Staff and Researchers

Public web page: Not specified

Start date: 24th Feb 2020

End date: 23rd Feb 2023

The New Medicines for Trypanosomatidic Infections - NMTrypI project aimed at obtaining new candidate drugs against Trypanosomatidic infections with appropriate efficiency from the lead phase to the final preclinical phase that are more accessible to patients.

WooBAdh project aims to study the feasibility of replacing formaldehyde in wood adhesives by natural components derived from wood or other vegetable matter. The consortium will develop new bioadhesives which are able to provide a holistic solution to the current emissions challenges facing the wood-based composites industry. The proposed solution is focused on different modifications of polyphenols, namely lignin and tannins, for producing bioadhesives that do not contain formaldehyde in its ...

No description specified

Programme: MIT Superfund Research

Public web page: Not specified

OBJECTIVE: To summarise an overview of existing evidence between Chinese medicine and polycystic ovary syndrome (PCOS),and to evaluate the strength and validity of these associations. METHODS: We retrieved systematic evaluations and meta-analyses of randomized controlled trials(RCT) evaluating Chinese herbal interventions in polycystic ovaries, including the use of decoctions or Chinese patent medicines. The quality of these systematic evaluations was evaluated using AMSTAR2 tools, while ovulation ...

Programme: An overview of systematic reviews of treatment of polycystic ovary syndrome with Chinese medicine

Public web page: Not specified

Start date: 1st Dec 2020

End date: 1st May 2021

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