Projects

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205 Projects found

Using standard systems biology methodologies a 14-compartment dynamic model was developed for the Corona virus epidemic. The model predicts that: (i) it will be impossible to limit lockdown intensity such that sufficient herd immunity develops for this epidemic to die down, (ii) the death toll from the SARS-CoV-2 virus decreases very strongly with increasing intensity of the lockdown, but (iii) the duration of the epidemic increases at first with that intensity and then decreases again, such that
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Programme: Model repository for M4 (Make Me My Model) clients of ISBE

Public web page: Not specified

Start date: 1st Mar 2020

End date: 24th Mar 2023

MESI-STRAT: Systems Medicine of Metabolic-Signaling Networks -A New Concept for Breast Cancer Patient Stratification.
Breast cancer is a complex disease with high prevalence in the European Union and world-wide. 75%-80 of the patients have estrogen receptor-positive (ER)-positive tumors and are treated with endocrine therapies. Endocrine therapies, which block ER-driven tumor growth, show high efficacy. Yet, a significant proportion of the patients will eventually relapse with metastatic breast
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Programme: This Project is not associated with a Programme

Public web page: http://www.mesi-strat.eu

nfdi4health aims to create the most comprehensive inventory of German epidemiological, public health and clinical trial data to date. It builds a centralised data catalogue with elaborate search functionalities, sophisticated data access management, and a data analysis toolbox, while respecting stringent requirements for privacy concerning personal health data. Standardisation services ensure a high degree of interoperability. Use cases covering prototypical study types and areas of research show
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The project addresses the generation and establishment of programmed pacemaker cells for an in vitro drug testing possibility to perform predictive tests. This may lead to an improved treatment of cardiac arrhythmias or an accurate identification of potential drug molecules at a very early stage of development. Important benefits will arise in verifying the safety of a wide variety of medicines while reducing animal testing. For more information you may visit our project website at
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CEPOPA envisions a sustainable cascade one-pot process for the synthesis of optically pure amines from alcohols and/or alkynes, using enzymes immobilized onto catalytically active nanomaterials. In the framework of the project, efficient chemoenzymatic processes will be developed for the synthesis of a set of amines that can be used as building blocks for pharmaceuticals or biomaterials.

Programme: Hellenic Foundation for Research and Innovation - Supporting academic Staff and Researchers

Public web page: Not specified

Start date: 24th Feb 2020

End date: 23rd Feb 2023

Valorization of mussel processing water into bioplastics

Programme: WooBAdh

Public web page: Not specified

Start date: 9th Nov 2020

End date: 9th Nov 2021

Here we share resources and best practices to develop a disease map for COVID-19. The project is progressing as a broad community-driven effort. We aim to establish a knowledge repository on virus-host interaction mechanisms specific to the SARS-CoV-2. The COVID-19 Disease Map is an assembly of molecular interaction diagrams established based on literature evidence.

This project bundles information about COVID-19 related studies and tools in Germany. It intends to provide an information hub for the different initiatives, their aims, their processes, standards and study protocols, as well as their available data and metadata.
It is initiated by the German National Research Data Infrastructure for Personal Health Data (nfdi4health), a consortium that plans to establish a concept for a federated research data infrastructure for personal health data in Germany.
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The group around Nicole Radde specializes in the modeling, analysis, and simulation of biochemical systems. This especially includes parameter optimization and identification.

PoLiMeR is funded through the EU Marie Skłodowska-Curie Innovative Training Network (ITN), which drives scientific excellence and innovation. ITNs bring together universities, research institutes, industry and clinical partners from across the world to train researchers to doctorate level.

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease
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Programme: This Project is not associated with a Programme

Public web page: http://polimer-itn.eu/

Identification of genomic variation in perennial ryegrass

Programme: ILVO test

Public web page: Not specified

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

FAIRDOM will establish a support and service network for European Systems Biology. We will serve projects in standardising, managing and disseminating data and models in a FAIR manner: Findable, Accessible, Interoperable and Reusable.

Programme: FAIRDOM

Public web page: http://fair-dom.org/

Start date: 1st Nov 2014

No description specified

Programme: COMBINE (Computational Modeling in Biology Network)

Public web page: Not specified

No description specified

Programme: ERNEST - European Research Network on Signal Transduction

Public web page: Not specified

optogenetic control of plant signaling

Programme: Synthetic Biology HHU

Public web page: Not specified

Start date: 24th Jun 2020

Background- Thermophilic organisms are composed of both bacterial and archaeal species. The enzymes isolated from these species and from other extreme habitats are more robust to temperature, organic solvents and proteolysis. They often have unique substrate specificities and originate from novel metabolic pathways. Thermophiles as well as their stable enzymes (‘thermozymes’) are receiving increased attention for biotechnological applications.

The proposed project will establish thermophilic in
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Centre for Digital Life Norway (DLN) project 'OXYMOD - Optimized oxidative enzyme systems for efficient conversion of lignocellulose to valuable products'

No description specified

Programme: Systems Brewology

Public web page: Not specified

This is a sandbox where DigiSal members can learn to use the SEEK.

Tutorial document: http://tinyurl.com/seek-ds17

The SEEK is a web interface to a database of research "assets" organised in a hierarchical "ISA structure" (investigation-study-assay) [1].
These are further organised into projects and programmes.

* Programme = Overarching research theme (The Digital Salmon)
* Project = Research grant (DigiSal, GenoSysFat)
* Investigation = a particular biological process, phenomenon or thing
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Salmon farmed on modern feeds contains less of the healthy, long-chain fatty acids (EPA and DHA) than before. Up until the turn of the millennium, farmed salmon were fed fish oil as a replacement for their omega-3 rich natural prey. However, fish oil is now a scarce resource, and more than half of the fat in modern feeds comes from plant oils that are inexpensive, but devoid of long-chain omega-3 fatty acids. How can we increase the omega-3 content of salmon on sustainable feeds?

One option is
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Towards the Digital Salmon: From a reactive to a pre-emptive research strategy in aquaculture (DigiSal)

Salmon farming in the future must navigate conflicting and shifting demands of sustainability, shifting feed prices, disease, and product quality. The industry needs to develop a flexible, integrated basis of knowledge for rapid response to new challenges. Project DigiSal will lay the foundations for a Digital Salmon: an ensemble of mathematical descriptions of salmon physiology, combining
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Programme: IDPfun Test programme

Public web page: Not specified

Start date: 1st Mar 2018

Hidden project

Programme: Test program

Public web page: Not specified

Microalgae Microbiomes: A natural source for the prevention and treatment of diseases in aquaculture

Aquaculture is one of the fastest growing food sectors in the world. In order to guarantee continuous, efficient and sustainable production and to safeguard the growth of this important sector, its protection from biological threats is crucial.
Within the AquaHealth project, an international consortium of highly experienced partners will assemble and apply an advanced meta’omics toolbox on the
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Programme: BlueBio ERA-NET COFUND

Public web page: https://bluebioeconomy.eu/wp-content/uploads/2020/04/AquaHealth.pdf

Start date: 1st May 2020

End date: 30th Apr 2023

No description specified

Programme: This Project is not associated with a Programme

Public web page: Not specified

Testing project creation

Programme: Test program

Public web page: Not specified

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