Projects

Conditions, online data and Raman spectra

Endometriosis research done by the Griffith lab (MIT) and the Goods lab (Dartmouth)

ABSTRACT – OVERALL The primary focus of the MIT/DFCI Center for Systems Biology of Glioblastoma is to understand the intersections between neurons, immune cells, and tumor cells in this deadly tumor. The lack of response to immunotherapy strategies despite prominent infiltrates of immune cells in many GBM highlights the immuno- suppressive nature of the GBM microenvironment and the importance of more clearly understanding the dynamic interactions at the tumor/immune interface. Similarly, interactions ...

Chronic kidney disease (CKD) affects around 9% of the global population and is the 12th leading cause of death (GBD Chronic Kidney Disease Collaboration 2020). Diabetic kidney disease (DKD) is the most common form of CKD, responsible for nearly half of all end-stage renal disease (ESRD) cases (Samsu 2021). Despite its high burden, progress in developing effective therapies has been slow, largely due to limited understanding of the underlying molecular mechanisms.

DKD is driven by complex and ...

The mission of the Virtual Human Platform is to improve the prediction of the potential harmful effects of chemicals and pharmaceuticals based on a holistic, interdisciplinary definition of human health by developing the Virtual Human Platform and accelerating the transition from animal-based testing to innovative safety assessment. The Virtual Human Platform integrates data on human physiology, chemical characteristics and perturbations of biological pathways, for the first time in an inclusive ...

Mission: We perform cutting-edge research on data generated by novel biomolecular technologies to address questions in pneumology. Towards this, we use biological high-throughput data, i.e., OMICs data, to gain insights into molecular and phenotypic traits and diseases using computational methods. We combine data, methodology and their applications in pneumology through interdisciplinary collaboration with mathematicians, computer scientists, biologists and physicians.

Check Out eLabFTW integration

Vesicle formation by Pseudomonas, their characterization and interaction with the host.

reNEW

3T3 murine embryonic fibroblasts are used as feeder layers to support the proliferative potential of human primary keratinocytes during in vitro expansion for cell and gene therapy applications. To identify signals mediating this function, we analyzed fibroblast protein content using mass spectrometry. We compared the proteome of lethally irradiated fibroblasts used as feeder layers in two conditions: standard quality (SQ-FL) and low quality (LQ-FL) fibroblasts. Our findings highlight differences ...

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Function, control and engineering of microbial methylotrophy (FUNCEMM) is a project bringing together 2 teams from France and Austria focusing on synthetic methylotrophy.

This is a test project

Dies ist eine Beschreibung der Data Request DR_Levels

SUSPHIRE aims to provide a sustainable, low-cost biomanufacturing platform for the commercial production of insect pheromones.

Synthetic biology data management spreadsheet: https://fairdomhub.org/data_files/6036

A collaborative space to document, manage, and share BullNet’s data, models, protocols, and/or results.