Models

275 Models visible to you, out of a total of 505

Copasi file chronic inflammation Abulikemu et al 2020 (altered units TNF and MMP8); see supplemntal material:
TNF and MMP7 concentration upgrade of the models
All computations for the present paper were completed by using the model prepared and tested in Abulikemu et al 2018. Then, little attention was paid to the unit in which concentrations were expressed, except for the concentration of fibroblasts, which we found important for modelling the effect of confluency. This led to a predicted TNF
...

Creators: Hans Westerhoff, Abulikemu Abudukelimu and Matteo Barberis

Contributor: Hans Westerhoff

Copasi file chronic inflammation Abulikemu et al 2020 (altered units TNF and MMP8); see supplemntal material:
TNF and MMP7 concentration upgrade of the models
All computations for the present paper were completed by using the model prepared and tested in Abulikemu et al 2018. Then, little attention was paid to the unit in which concentrations were expressed, except for the concentration of fibroblasts, which we found important for modelling the effect of confluency. This led to a predicted TNF
...

Creators: Hans Westerhoff, Ablikim Abulikemu, Matteo Barberis

Contributor: Hans Westerhoff

This is a model about a ROS network that exhibits five design principles, and has been calibrated so as to predict quantitatively various steady state concentrations. 10191125.

Instructions
RUN the model for steady state.
For the Menadione experiment set the initial concentration of 'Menadione' species to experimental dosing i.e. 100 000 nM (0.1 mM) and make the simulation type "reaction" for both the species i.e. 'Menadione' and 'Menadione_internal'. Then run for 24 hr i.e. 1500 minutes approx.
...

Creators: Hans Westerhoff, Raju Prasad Sharma, Alexey Kolodkin

Contributor: Hans Westerhoff

Dynamic model of glycolysis, pyruvate metabolism and NoxE. The model is parameterized by selecting the best out of 100 parameter set using Copasi's Genetic algorithm with 1000 itterations and 500 simmulatanious models.

Model that can be used to obtain the figures of Abudulikemu et al 2018:
Abudukelimu, A., Barberis, M., Redegeld, F.A., Sahin, N., and Westerhoff, H.V. (2018). Predictable Irreversible Switching Between Acute and Chronic Inflammation. Front Immunol 9, 1596.

Creators: Hans Westerhoff, Ablikim Abudukelimu

Contributor: Hans Westerhoff

(Abudulikemu et al 2000 (also 2018) Standard model of acute mode Figure 32.

Creators: Hans Westerhoff, Ablikim Abudukelimu

Contributor: Hans Westerhoff

Particularly figure 2 of of Abudulikemu et al 2020 in press

Creator: Hans Westerhoff

Contributor: Hans Westerhoff

NetLogo desktop version of Breast cancer development agent based model

Creator: Hannah O'Keefe

Contributor: Hannah O'Keefe

desktop version of NetLogo model of cellular senescence in dermal layer of skin

Creator: Hannah O'Keefe

Contributor: Hannah O'Keefe

Originally submitted model file for PLaSMo accession ID PLM_73, version 1

Creators: BioData SynthSys, Yin Hoon Chew

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_75, version 1

Creators: BioData SynthSys, Yin Hoon Chew

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_74, version 1

Creators: BioData SynthSys, Yin Hoon Chew

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_76, version 1

Creators: BioData SynthSys, Yin Hoon Chew

Contributor: BioData SynthSys

The consensus GEM for Saccharomyces cerevisiae, version 8.3.3, maintained on https://github.com/SysBioChalmers/yeast-GEM.

Creator: Eduard Kerkhoven

Contributor: Eduard Kerkhoven

BPG stability notebook

Creator: Jacky Snoep

Contributor: Jacky Snoep

No description specified

Creator: Alexey Kolodkin

Contributor: Alexey Kolodkin

PGK model for S. solfataricus

Creator: Jacky Snoep

Contributor: Jacky Snoep

A small model representing the core carbon network in each cell. For more detail on the model creation see [1]. The model is written in SBML using the RAM extension for use in deFBA. Compatible python software for simulation can be found at https://tinyurl.com/yy8xu4v7

[1] S. Waldherr, D. A. OyarzĂșn, A. Bockmayr. Dynamic optimization of metabolic networks coupled with gene expression. In: Journal of Theoretical Biology, 365(0): 469 - 485.

Creators: Henning Lindhorst, Steffen Waldherr

Contributor: Henning Lindhorst

This model was created to showcase all functions of the SBML extension RAM. The model can be unr in deFBA with the python software deFBA-Python. The software is freely available at at https://tinyurl.com/yy8xu4v7

Creator: Henning Lindhorst

Contributor: Henning Lindhorst

A minimal model showing the core of resource allocation models as it can either be invested in enzymatic machinery or single biomass components with the best yield. The model is written in SBML using the RAM extension for use in deFBA. Compatible python software for simulation can be found at https://tinyurl.com/yy8xu4v7

Creator: Henning Lindhorst

Contributor: Henning Lindhorst

This SBML file uses the RAM extension and contains a minimal genome scaled model for Saccharomyces cerevisiae. The model is based of Yeast 6.06 and was published first in A.-M. Reimers Thesis "Understanding metabolic regulation and cellular resource allocation through optimization".

Creators: Henning Lindhorst, Alexandra-M. Reimers

Contributor: Henning Lindhorst

Originally submitted model file for PLaSMo accession ID PLM_71, version 2

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Simplified model file for PLaSMo accession ID PLM_9, version 2 (use simplified if your software cannot read the file, e.g. Sloppy Cell)

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_9, version 2

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Simplified model file for PLaSMo accession ID PLM_9, version 1 (use simplified if your software cannot read the file, e.g. Sloppy Cell)

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_9, version 1

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Simplified model file for PLaSMo accession ID PLM_10, version 1 (use simplified if your software cannot read the file, e.g. Sloppy Cell)

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_10, version 1

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Simplified model file for PLaSMo accession ID PLM_8, version 1 (use simplified if your software cannot read the file, e.g. Sloppy Cell)

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

Originally submitted model file for PLaSMo accession ID PLM_8, version 1

Creators: BioData SynthSys, Andrew Millar, Andrew Millar

Contributor: BioData SynthSys

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