Models

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334 Models visible to you, out of a total of 573

First version of enzyme-constrained model (ecModel) for Escherichia coli

Creator: Cheewin Kittikunapong

Submitter: Cheewin Kittikunapong

NetLogo desktop version of Breast cancer development agent based model

Creator: Hannah O'Keefe

Submitter: Hannah O'Keefe

Interactions of Nsp4 and Nsp6 proteins of SARS-CoV-2.

Creators: Arnau Montagud, Miguel Ponce-de-Leon

Submitter: Marek Ostaszewski

Interactions of the SARS-CoV-2 Orf3a with human proteins, especially in the context of the HOPS Complex.

Creator: Muhammad Naveez

Submitter: Marek Ostaszewski

A diagram of Nsp9 interactions.

Creators: Noriko Hiroi, Yusuke Hiki, Takahiro G. Yamada, Akira Funahashi

Submitter: Marek Ostaszewski

Orf10 of SARS-CoV-2 and its interaction with the Cul2 pathway.

Creators: Jan Hasenauer, Leonard Schmiester, Paul Stapor

Submitter: Marek Ostaszewski

Pyrimidine deprivation and immune response related to human coronavirus infection

Creators: Zsolt Bocskei, Franck Augé, Anna Niarakis

Submitter: Marek Ostaszewski

The relation of the interferon 2 pathway and SARS-CoV-2.

Creators: Anna Niarakis, Vidisha Singh, Sara AGHAMIRI

Submitter: Marek Ostaszewski

The Interferon-lambda (IFNL) map describes the action of the drug candidate IFNL on intra- and intercellular signal transduction under SARS-CoV-2.

Creators: Marius Rameil, Vanessa Nakonecnij, Marta Conti

Submitter: Marek Ostaszewski

The pathway of heme metabolism under COVID-19, involving Orf3a and Orf9c

Creators: Julia Somers, Emek Demir

Submitter: Marek Ostaszewski

The mechanisms of the Electron Transport Chain under COVID-19, including Nsp7, Nsp8 and Orf9c

Creator: Julia Scheel

Submitter: Marek Ostaszewski

SARS-CoV-2 impact on the ER stress

Creators: Cristobal Monraz, Inna Kuperstein, Barbara Brauner

Submitter: Marek Ostaszewski

Thrombotic complications and coagulopathy in COVID-19

Creators: Marek Ostaszewski, Goar Frischmann, Gisela Fobo, Corinna Montrone

Submitter: Marek Ostaszewski

Model associated with the following:

Hannah A Kinmonth-Schultz, Melissa J S MacEwen, Daniel D Seaton, Andrew J Millar, Takato Imaizumi, Soo-Hyung Kim, An explanatory model of temperature influence on flowering through whole-plant accumulation of FLOWERING LOCUS T in Arabidopsis thaliana, in silico Plants, Volume 1, Issue 1, 2019, diz006, https://doi.org/10.1093/insilicoplants/diz006

Creator: Hannah Kinmonth-Schultz

Submitter: Hannah Kinmonth-Schultz

To obtain each of the figure 2A - 2E please download "Main Figure Copasi" and open the sub-directory with the name of the sub-figure, run the Copasi files and the time dependence simulation. This will reproduce the figure in this paper.

Creators: Alexey Kolodkin, Hans Westerhoff, Raju Prasad Sharma

Submitter: Alexey Kolodkin

No description specified

Creators: Alexey Kolodkin, Hans Westerhoff, Raju Prasad Sharma

Submitter: Alexey Kolodkin

No description specified

Creators: Alexey Kolodkin, Hans Westerhoff, Raju Prasad Sharma

Submitter: Alexey Kolodkin

No description specified

Creators: Alexey Kolodkin, Hans Westerhoff, Raju Prasad Sharma

Submitter: Alexey Kolodkin

COVID-19 Causal Networks: The SIGNOR team has curated the causal relationships that, according to available evidence, are likely to be relevant for the COVID-19 pathology. The perturbations caused by viral infection are integrated into the cell networks. Evidence obtained using related human coronaviruses diseases such as SARS and MERS are also mapped to the networks. Most of these are indirect relationships as few mechanistic details are clarified to date. As new evidence will be published, it
...

Creators: Luana Licata, Marta Iannuccelli, University of Rome Tor Vergata, IT

Submitter: Marek Ostaszewski

The role of the interaction between the SARS-CoV-2 Spike protein and the renin-angiotensin pathway, in particular human ACE2 in pulmonary blood pressure regulation

Creators: Enrico Glaab, Andreas Ruepp, Corinna Montrone, Gisela Fobo

Submitter: Marek Ostaszewski

Pathway: Assembly of the Replication Transcription Complex and Transcription

Creators: Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber

Submitter: Marek Ostaszewski

Metabolic interactions of the SARS-CoV-2 Nsp14 with the human galactose, nicotinate and nicotinamide, and purine metabolism.

Creators: Alina Renz, Andreas Dräger

Submitter: Marek Ostaszewski

The impact of SARS-CoV-2 on the apoptosis pathway

Creators: Anna Niarakis, Vidisha Singh, Sara AGHAMIRI

Submitter: Marek Ostaszewski

Interactions of the SARS-CoV-2 E protein with human proteins in the context of histone acetylation.

Creator: Francesco Messina

Submitter: Marek Ostaszewski

Set of pathways encompassing the replication cycle of SARS-CoV-2: attachment, entry, translation, transcription, replication, assembly and release.

Creators: Marcio Acencio, Alexander Mazein

Submitter: Marek Ostaszewski

A diagram of JNK pathway in COVID-19.

Creator: Daniela Börnigen

Submitter: Marek Ostaszewski

A diagram encoding PAMP signaling relevant to COVID-19/SARS-CoV-2

Creator: Matti Hoch

Submitter: Marek Ostaszewski

The pathways focused on SARS-CoV infections curated in Reactome.
These pathways are work-in-progress.

Creators: Marc Gillespie, Robin Haw, Peter D'Eustachio

Submitter: Marek Ostaszewski

Mechanisms related to COVID-19 virus replication cycle, constructed using the mEPN graphical notation.

Creators: Liam Fergusson, Tom Freeman

Submitter: Marek Ostaszewski

The novel coronavirus (SARS-CoV-2) currently spreads worldwide, causing the disease COVID-19. The number of infections increases daily, without any approved antiviral therapy. The recently released viral nucleotide sequence enables the identification of therapeutic targets, e.g., by analyzing integrated human-virus metabolic models. Investigations of changed metabolic processes after virus infections and the effect of knock-outs on the host and the virus can reveal new potential targets. Results:
...

Creators: Alina Renz, Andreas Dräger

Submitter: Martin Golebiewski

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