Programmes

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134 Programmes found
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Projects: Pan-cancer multiSOM project

Web page: Not specified

The Snoep Lab’s core research efforts are in Computational Systems Biology; a combined experimental, modeling and theoretical approach to quantitatively understand the functional behavior of Biological Systems resulting from the characteristics of their components. Our main focus is on metabolism, of human pathogens such as Plasmodium falciparum, Mycobacterium tuberculosis, but also of breast cancer cell lines, and on modelling disease states such as glucose homeostatis in type 2 diabetes, and ...

Projects: Whole body modelling of glucose metabolism in malaria patients, Steroid biosynthesis, Yeast glycolytic oscillations, Computational pathway design for biotechnological applications, Glucose metabolism in cancer cell lines

Web page: http://www.sun.ac.za/english/faculty/science/biochemistry/research/snoep-group

The recent COVID19 pandemic infection has undisclosed long-standing issues in the translation of drugs from animals to humans or vice-versa. Nearly 75% of emerging human infections worldwide originated from animals; existing drugs for human and animal (H&A) vector-borne diseases (VBD) are scarce, with limited efficacy, toxicity, and finite resources. Emerging environmental problems in pharmaceutical use/manufacturing increase attention in the field. The two drug pipelines are developed ...

Projects: WG1 - Compound libraries coordination and integration of compound design, WG2 - Integration of early phase studies and low environmental impact actions, WG3 - Coordination of in vitro-to-in vivo translation of OneHealth leads and candidates, WG4 - Integration of R&D process-environmental studies and translation in informed whitepaper, WG5 - Promote dissemination, WG6 - Promote the transfer of knowledge

Web page: Not specified

Synthetic Biology and Biosystems Control Lab (SB2CL). We focus our research on applications of systems engineering and control to Systems and Synthetic Biology, and Bioprocesses estimation and control. Our group is member of the Institute for Automatica and Industrial Informatics (ai2) at the Universitat Politècnica de València (Spain).

Our main interests are in:

  • Dynamic regulation of gene expression for control of variability in gene expression and regulation of novel routes to obtain complex ...

Projects: BioDynamics

Web page: http://sb2cl.ai2.upv.es

No description specified

Projects: NL-Bioimaging FAIR Metadata Templates

Web page: Not specified

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Projects: MultiDefence - sLoLa

Web page: Not specified

Background. RB1 is a paradigm gene for heritable cancer. Almost all RB1 mutation-carriers develop retinoblastoma (heritable-Rb-patient) during childhood and many heritable-Rb-survivors develop second primary malignancies (SPMs; notably sarcomas and melanomas) throughout life, which are often fatal. To date, no standard protocols are available for early detection of SPMs. Recently, blood-based cancer tests have opened up encouraging new possibilities for surveillance. We have developed novel ...

Projects: NIRBTEST

Web page: Not specified

RNA-Seq projects from SECARNA

Projects: Investigation of the activity of antisense oligonucleotides targeting multiple genes

Web page: Not specified

No description specified

Projects: Testing tools for research data management

Web page: Not specified

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Projects: Not specified

Web page: https://isbe.nl

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Projects: JUANGMC

Web page: Not specified

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Projects: Public project

Web page: Not specified

To systematically evaluate the general efficacy of nape acupuncture combined with rehabilitation training for the treatment of post-stroke dysphagia and in the recovery of swallowing function.

Projects: The Effect of Nape Acupuncture Combined with Rehabilitation Training on Dysphagia After Stroke: A Meta-analysis

Web page: Not specified

Oxidative stress is an important mechanism of cerebral ischemia-reperfusion injury. Ferroptosis caused by iron overload after cerebral ischemia-reperfusion is considered a common cause of oxidative stress. A large number of recent studies have shown that electroacupuncture (EA) can regulate the expression of inflammatory factors, and the use of electroacupuncture preconditioning can produce a protective effect, which can reduce injury after cerebral ischemia and reperfusion. We aimed to assess ...

Projects: Electroacupuncture preconditioning reduces oxidative stress in the acute phase of cerebral ischemia-reperfusion in rats by regulating iron metabolism pathways

Web page: Not specified

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Projects: CC-TOP

Web page: Not specified

The principal research aim of iPLACENTA is to improve our ability to study, model and visualise the placenta. This will contribute to developing diagnostic tests and therapies for pregnancy complications such as preeclampsia and intrauterine growth restriction (IUGR). Placental defects are thought to be the cause of many major pregnancy complications, such as preeclampsia and intra-uterine growth restriction. Preeclampsia affects between 5 and 8 out of every 100 pregnant women and claims the lives ...

Projects: Molecular characterization and angiogenic properties of extracellular vesicles in healthy and preeclamptic amniotic fluid, Overexpression of microRNAs miR-25-3p, miR-185-5p and miR-132-3p in Late Onset Fetal Growth Restriction, Validation of Results and Study of the Biochemical Pathways Involved, Comparative Proteome Profile of Placental Sub-anatomical regions, The deregulated interplay of complement system and antioxidant activity as a driver of adverse pregnancy outcomes

Web page: https://www.iplacenta.eu/

No description specified

Projects: Clostridium beijerinckii pan-genome

Web page: Not specified

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Projects: Hello

Web page: Not specified

The Deutsche Forschungsgemeinschaft (DFG) is the self-governing organisation for science and research in Germany. It serves all branches of science and the humanities. In organisational terms, the DFG is an association under private law. Its membership consists of German research universities, non-university research institutions, scientific associations and the Academies of Science and the Humanities.

Projects: SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers

Web page: https://www.dfg.de/en/index.jsp

Work of the Gygli group...

Projects: Test Project (dummy), Towards Reproducible Enzyme Modeling

Web page: Not specified

No description specified

Projects: Not specified

Web page: https://www.wikipathways.org

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