Programmes

To summarise an overview of existing evidence between Chinese medicine and polycystic ovary syndrome (PCOS)，and to evaluate the strength and validity of these associations. We retrieved systematic evaluations and meta-analyses of randomized controlled trials(RCT) evaluating Chinese herbal interventions in polycystic ovaries, including the use of decoctions or Chinese patent medicines. The quality of these systematic evaluations was evaluated using AMSTAR2 tools, while ovulation rate, pregnancy ...

Infection management requires the development of research programs that operate with the logic of network medicine for implementation of complex strategies to make the best use of availability of "omics-based" technologies, development of systems diagnostics, possibility of using innovative (and at the same time extremely expensive) drugs. This study group is composed by many experts with high knowledge in infectious diseases and “omics” competences at at Italian National Institute for Infectious ...

This page is dedicated to the bioinformatics analysis and computational modelling related to Covid-19 disease map pathways.

We develop macrophage logical models to represent the activation/polarization of this immune cell. Interactions are manually curated with available macrophage literature. The models are mainly built and analyzed in GINsim. But other resources are used to integrate specific pathways or small modules (CasQ software) and to analyze the logical models (CoLoMoTo Notebooks).

We used the Neo4j graph database approach to integrate the content of the COVID-19 Disease Map diagrams to efficiently access, query and manage the content of these diagrams and enable communication with external resources, such as Reactome and Recon, that already provide support via a similar environment.

this is personal project

Inactivation of the VHL tumor suppressor gene is linked to the development of several different tumor types in humans, including hemangioblastomas of the retina and central nervous system, clear cell renal carcinoma, pancreatic cysts, pheochromocytoma. Biochemical studies revealed that pVHL interacts with several different proteins serving as a multipurpose adaptor protein that engages in multiple protein-protein interactions to control diverse transcriptional-dependent and transcriptional-independent ...

IDPfun is an international consortium aiming to extend our knowledge on the functions of intrinsically disordered proteins (IDPs). Starting from available state of the art computational tools and databases, which have been mostly developed by IDPfun participants, it aims to drive a new level of IDP characterization.

This is a test programme, which will be used to learn how to use and evaluate Fairdom Hub for NORCE Environment's purposes, as part of the SIS-OMICS project.

nfdi4health aims to create the most comprehensive inventory of German epidemiological, public health and clinical trial data to date. It builds a centralised data catalogue with elaborate search functionalities, sophisticated data access management, and a data analysis toolbox, while respecting stringent requirements for privacy concerning personal health data. Standardisation services ensure a high degree of interoperability. Use cases covering prototypical study types and areas of research show ...

COST Action CA18133

BlueBio ERA-NET COFUND on the Blue Bioeconomy

The Hellenic Foundation for Research and Innovation is a new institution through which a profound reforming effort is being undertaken in the field of Research and Innovation in the country. The Organization supports unrestricted research (the systematic inquiry born of scientific curiosity) and new researchers by providing scholarships for doctoral candidates, as well as research projects for post-doctoral students, Researchers and Faculty Members. Through H.F.R.I., the research and academic ...

Bringing 3D Additive Manufacturing from the macroscale to the micro-, nano-, and eventually to the molecular scale and at applying these technologies

The aim is to bundle the information about the manifold of COVID-19 centered initiatives offering tools and studies.

The Disease Maps Project is designed as a large-scale community effort. It is a network of groups that work together in order to better understand disease mechanisms. The project exchanges best practices, share information, develop tools to make it easier for all the involved groups to achieve their goals.

ERA CoBioTech is an ERA-Net Cofund Action under H2020, which aims to strengthen the European Research Area (ERA) in the field of Biotechnology through enhanced cooperation and coordination of different national and regional research programs, promoting systems biology and synthetic biology as technology driversto speed up research and innovation in industrial biotechnology.

› By maximizing synergies between current mechanisms of biotechnology research funding in Europe; › By fostering the exchange ...

Using kinetic models to study the central carbon metabolism in pseudomonas putida, both for metabolite production and understanding the impact of certain perturbations.