The Hellenic Foundation for Research and Innovation is a new institution through which a profound reforming effort is being undertaken in the field of Research and Innovation in the country. The Organization supports unrestricted research (the systematic inquiry born of scientific curiosity) and new researchers by providing scholarships for doctoral candidates, as well as research projects for post-doctoral students, Researchers and Faculty Members. Through H.F.R.I., the research and academic community is, for the first time, actively involved in shaping the country’s research and innovation policy without thematic or geographical exclusions, but with the sole criterion of scientific quality and excellence. H.F.R.I. was created out of the vital need to support young scientists and as a necessary tool in reversing the outflow of outstanding scientists abroad. Indeed, one of H.F.R.I.’s key goals is to impede the scientific and economic haemorrhage that the loss of gifted Greek researchers entails.
In order to achieve its goals, H.F.R.I.: • Grants scholarships for doctoral dissertations and post-doctoral studies • Funds high quality research projects in which post-graduate students, researchers and faculty members are principal investigators • Finances the acquisition of research equipment • Enables Universities, TEIs, research and technology stakeholders, to access innovative research program financing • Supports the creation and operation of start-ups in order to utilize research results
Web page: http://www.elidek.gr/en/homepage/Funding details:
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Institutions: University of Crete
Institutions: University of Cretehttps://orcid.org/0000-0001-5811-368X
Assist. Prof. of Enzyme Technology Laboratory, Department of Chemistry, University of Crete, Greece
CEPOPA envisions a sustainable cascade one-pot process for the synthesis of optically pure amines from alcohols and/or alkynes, using enzymes immobilized onto catalytically active nanomaterials. In the framework of the project, efficient chemoenzymatic processes will be developed for the synthesis of a set of amines that can be used as building blocks for pharmaceuticals or biomaterials.
Public web page: Not specified
Start date: 24th Feb 2020
End date: 23rd Aug 2023
Organisms: Escherichia coli
Objectives: Empowering smooth implementation and fruitful completion of all WPs and tasks. Implementation of a data management plan for efficient dissemination under F.A.I.R. principles.
Description of Work: The PI of the project with the heads of the collaborating groups will closely monitor the progress of the technical and administrative tasks and it will implement actions to correct any deviation from the established work-plan. The whole group will meet regularly every six months or more ...
Objectives: Establishment of the chemoenzymatic process with the best GO-ATA hybrid catalysts. Highlighting of the potential of the process in semi-preparative scale.
Description of Work: The best hybrid catalysts identified in WP3 will be investigated in coupled one-pot reactions selected in WP1, in batch and continuous flow reactors. The productivity of the system will be optimized with response surface methodology (RSM), for parameters such as temperature, duration, substrate concentration ...
Objectives: Development of efficient ATA immobilization approach. Production of a hybrid catalyst of high catalytic efficiency.
Description of Work: Τhe ATAs selected in WP2 will be expressed, purified and covalently and/or non-covalently immobilized on the GO selected in WP1. The catalytic behavior (in terms of catalytic activity, stability and reusability) and the structural implications of the immobilization will be investigated. For comparison purposes, the non-optimized ATAs (prior to the ...
Objectives: Identification of amine transaminases (ATAs) able to catalyze efficiently the amination of a desired set of ketones and aldehydes (expected products of GO oxidation). Optimization of the most potent biocatalysts, in terms of catalytic efficiency, stability, availability of functional groups for covalent immobilization.
Description of Work: ATAs from our construct selection (>30 wild-type and variants of both (R)- and (S)-enantioselectivity) with different substrate selectivity will ...
Objectives: Protocol identification and establishment for the synthesis of high-performing catalytic GO in the desired oxidation reactions under mild conditions. Characterization of the most prominent materials synthesized and comparison to commercially available material.
Description of Work: Several established chemical methods will be used for the synthesis of GO. Each batch will be characterized, for instance for its C/O ratio, surface area and conductivity. The catalytic profile of the ...
Date Published: 6th Dec 2021
Publication Type: Journal
Date Published: 13th Jul 2021
Publication Type: Journal
Citation: Chemistry Teacher International 0(0),000010151520210011
Date Published: 2021
Publication Type: Journal
Citation: Chem. Commun.,10.1039.D1CC04664K
Protein Engineering Congress EU
Start Date: 24th Nov 2020
End Date: 1st Dec 2020
Country: Not specified
City: Not specified