The Hellenic Foundation for Research and Innovation is a new institution through which a profound reforming effort is being undertaken in the field of Research and Innovation in the country. The Organization supports unrestricted research (the systematic inquiry born of scientific curiosity) and new researchers by providing scholarships for doctoral candidates, as well as research projects for post-doctoral students, Researchers and Faculty Members. Through H.F.R.I., the research and academic community is, for the first time, actively involved in shaping the country’s research and innovation policy without thematic or geographical exclusions, but with the sole criterion of scientific quality and excellence. H.F.R.I. was created out of the vital need to support young scientists and as a necessary tool in reversing the outflow of outstanding scientists abroad. Indeed, one of H.F.R.I.’s key goals is to impede the scientific and economic haemorrhage that the loss of gifted Greek researchers entails.
In order to achieve its goals, H.F.R.I.: • Grants scholarships for doctoral dissertations and post-doctoral studies • Funds high quality research projects in which post-graduate students, researchers and faculty members are principal investigators • Finances the acquisition of research equipment • Enables Universities, TEIs, research and technology stakeholders, to access innovative research program financing • Supports the creation and operation of start-ups in order to utilize research results
Web page: http://www.elidek.gr/en/homepage/
Funding details:Related items
- People (9)
- Projects (1)
- Institutions (1)
- Investigations (5)
- Studies (0+5)
- Assays (0+4)
- Data files (10+6)
- SOPs (0+3)
- Publications (3)
- Presentations (12)
- Events (7)
- Documents (11+7)
Assist. Prof. of Enzyme Technology Laboratory, Department of Chemistry, University of Crete, Greece
CEPOPA envisions a sustainable cascade one-pot process for the synthesis of optically pure amines from alcohols and/or alkynes, using enzymes immobilized onto catalytically active nanomaterials. In the framework of the project, efficient chemoenzymatic processes will be developed for the synthesis of a set of amines that can be used as building blocks for pharmaceuticals or biomaterials.
Programme: Hellenic Foundation for Research and Innovation - Supporting academic Staff and Researchers
Public web page: Not specified
Start date: 24th Feb 2020
End date: 23rd Aug 2023
Organisms: Escherichia coli
Objectives: Empowering smooth implementation and fruitful completion of all WPs and tasks. Implementation of a data management plan for efficient dissemination under F.A.I.R. principles.
Description of Work: The PI of the project with the heads of the collaborating groups will closely monitor the progress of the technical and administrative tasks and it will implement actions to correct any deviation from the established work-plan. The whole group will meet regularly every six months or more ...
Snapshots: No snapshots
Objectives: Establishment of the chemoenzymatic process with the best GO-ATA hybrid catalysts. Highlighting of the potential of the process in semi-preparative scale.
Description of Work: The best hybrid catalysts identified in WP3 will be investigated in coupled one-pot reactions selected in WP1, in batch and continuous flow reactors. The productivity of the system will be optimized with response surface methodology (RSM), for parameters such as temperature, duration, substrate concentration ...
Snapshots: No snapshots
Objectives: Development of efficient ATA immobilization approach. Production of a hybrid catalyst of high catalytic efficiency.
Description of Work: Τhe ATAs selected in WP2 will be expressed, purified and covalently and/or non-covalently immobilized on the GO selected in WP1. The catalytic behavior (in terms of catalytic activity, stability and reusability) and the structural implications of the immobilization will be investigated. For comparison purposes, the non-optimized ATAs (prior to the ...
Snapshots: No snapshots
Objectives: Identification of amine transaminases (ATAs) able to catalyze efficiently the amination of a desired set of ketones and aldehydes (expected products of GO oxidation). Optimization of the most potent biocatalysts, in terms of catalytic efficiency, stability, availability of functional groups for covalent immobilization.
Description of Work: ATAs from our construct selection (>30 wild-type and variants of both (R)- and (S)-enantioselectivity) with different substrate selectivity will ...
Snapshots: No snapshots
Objectives: Protocol identification and establishment for the synthesis of high-performing catalytic GO in the desired oxidation reactions under mild conditions. Characterization of the most prominent materials synthesized and comparison to commercially available material.
Description of Work: Several established chemical methods will be used for the synthesis of GO. Each batch will be characterized, for instance for its C/O ratio, surface area and conductivity. The catalytic profile of the ...
Snapshots: No snapshots
A brief summary of the first activity, proposed in our teaching sequence.
Creator: Ioannis Metaxas
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
A brief description of the second educational activity.
Creator: Ioannis Metaxas
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
A brief discription of the third educational activity.
Creator: Ioannis Metaxas
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The excel spreadsheet about the inherency of the size dependency of optical properties at the nanoscale
Creator: Ioannis Metaxas
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The excel spreadsheet about the inherency of the size dependency of optical properties at the nanoscale
Creator: Ioannis Metaxas
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The structure of was Transaminase of gamma-proteobacterium deposited in PDB under the code: 7p3t
Creator: Eleni Konia
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Data of the activity/pH profile of the under study enzymes
Creator: Eleni Konia
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Data for the photometric determination of the activity for the under study enzymes.
Creator: Eleni Konia
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Data file for the Pyridoxamine phosphate formation assay
Creator: Eleni Konia
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Data files for the kinetic resolution assay
Creator: Eleni Konia
Submitter: Ioannis Metaxas
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: Nikolaos Kaloudis, Panagiota Zygouri, Nikolaos Chalmpes, Konstantinos Spyrou, Dimitrios Gournis, Ioannis Pavlidis
Date Published: 6th Dec 2021
Publication Type: Journal
DOI: 10.3389/fctls.2021.803850
Citation:
Abstract (Expand)
Authors: Ioannis Metaxas, Emily Michailidi, Dimitris Stavrou, Ioannis V. Pavlidis
Date Published: 13th Jul 2021
Publication Type: Journal
Citation: Chemistry Teacher International 0(0),000010151520210011
Abstract (Expand)
Authors: Eleni Konia, Konstantinos Chatzicharalampous, Athina Drakonaki, Cornelia Muenke, Ulrich Ermler, Georgios Tsiotis, Ioannis V. Pavlidis
Date Published: 2021
Publication Type: Journal
DOI: 10.1039/D1CC04664K
Citation: Chem. Commun.,10.1039.D1CC04664K
Oral presentation given at Conference Amine 5.0
Creators: Nikolaos Kaloudis, Ioannis Pavlidis, Eleni Konia
Submitter: Nikolaos Kaloudis
Poster presentation in Conference Biocat 2022
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Oral presentation at the Conference Biotrans 2023
Creator: Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Oral presentation on EB Days 2023
Creators: Nikolaos Kaloudis, Ioannis Pavlidis, Eleni Konia
Submitter: Nikolaos Kaloudis
Poster presentation in Conference Biocat 2022
Creator: Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Poster presentation in Conference Biocat 2022
Creators: Eleni Konia, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Poster presentation at Biotrans 2021 Conference.
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Poster presentation on Conference Biotrans 2021
Creators: Eleni Konia, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Poster presentation at GRC Biocatalysis 2022
Creators: Ioannis Pavlidis, Eleni Konia
Submitter: Nikolaos Kaloudis
Poster presented in Conference BioCat 2022
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Poster presented in Protein Engineering Congress EU
Creators: Ioannis Pavlidis, Eleni Konia, Nikolaos Kaloudis
Submitter: Ioannis Pavlidis
Start Date: 7th Sep 2023 (7th Sep 2023 (Etc/UTC))
End Date: 9th Sep 2023 (9th Sep 2023 (Etc/UTC))
Event Website: Not specified
Country: Türkiye
City: Kars
Start Date: 25th Jun 2023 (25th Jun 2023 (Etc/UTC))
End Date: 29th Jun 2023 (29th Jun 2023 (Etc/UTC))
Event Website: Not specified
Country: France
City: La-Rochelle
Start Date: 28th Nov 2022 (28th Nov 2022 (Etc/UTC))
End Date: 30th Nov 2022 (30th Nov 2022 (Etc/UTC))
Event Website: Not specified
Country: Netherlands
City: Groningen
Start Date: 28th Aug 2022 (28th Aug 2022 (Etc/UTC))
End Date: 1st Sep 2022 (1st Sep 2022 (Etc/UTC))
Event Website: Not specified
Country: Germany
City: Hamburg
Start Date: 10th Jul 2022 (10th Jul 2022 (Etc/UTC))
End Date: 15th Jul 2022 (15th Jul 2022 (Etc/UTC))
Event Website: Not specified
Country: United States
City: Southern New Hampshire
Start Date: 19th Jul 2021 (19th Jul 2021 (Etc/UTC))
End Date: 22nd Jul 2021 (22nd Jul 2021 (Etc/UTC))
Event Website: Not specified
Country: Austria
City: Graz
Protein Engineering Congress EU
Start Date: 24th Nov 2020
End Date: 1st Dec 2020
Event Website: https://www.proteinengineeringcongresseu.com/events/protein-engineering-congress-eu-2020
Country: Not specified
City: Not specified
A technical report on the developed optimized protocol on the synthesis of highly catalytic GO
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: WP1: Graphene oxide screening, WP2: Transaminase screening and optimization
Studies: 2 hidden items
Assays: 2 hidden items
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The chemical part of the reaction was replaced by an enzymatic step.
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Partly completed.
Creators: Nikolaos Kaloudis, Ioannis Pavlidis
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creators: Nikolaos Kaloudis, Ioannis Pavlidis, Eleni Konia
Submitter: Nikolaos Kaloudis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Data Management Plan (v.1.0) of the project CEPOPA.
Investigations: No Investigations
Studies: No Studies
Assays: No Assays