IMPAcTB

Overview
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Web page: https://www.niaid.nih.gov/research/immune-mechanisms-protection-mycobacterium-tuberculosis

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Charles Demurjian

Projects: Hi-IMPAcTB, MIT SRP, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC)

Institutions: Massachusetts Institute of Technology

Huiming Ding

Projects: Hi-IMPAcTB, MIT SRP, MetNet

Institutions: Massachusetts Institute of Technology

Stuart Levine

Projects: MIT SRP, Hi-IMPAcTB, MetNet

Institutions: Massachusetts Institute of Technology

https://orcid.org/0000-0001-7363-562X

Francesca Licciardello

Projects: Hi-IMPAcTB, MetNet, MIT SRP

Institutions: MIT, Massachusetts Institute of Technology

Douaa Mugahid

Projects: Hi-IMPAcTB

Institutions: Massachusetts Institute of Technology

https://orcid.org/0000-0002-3455-2992

Dikshant Pradhan

Projects: Hi-IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology

Jake Schissel

Projects: Hi-IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

shuwang543

Projects: Hi-IMPAcTB

Institutions: University of Toronto

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Hi-IMPAcTB

About

This project houses all the publicly available datasets generated by the Hi-IMPAcTB consortium over the course of its 7+ years.

What is Hi-IMPAcTB?

Hi-IMPAcTB is an ambitious endeavor bringing together a team of international, interdisciplinary researchers to improve our understanding of host-pathogen interactions in the context of tuberculosis (TB). Funded by a multi-center contract from the NIH, the long-term goal of the consortium is to enable principled vaccine design by improving ...

Programme: IMPAcTB

Public web page: https://grantome.com/grant/NIH/75N93019C00071-0-9999-1

Organisms: Mus musculus, Homo sapiens, Macaca fascicularis, Macaca mulatta

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Massachusetts Institute of Technology

Country: United States

City: Not specified

Web page: Not specified

MIT

Country: United States

City: Not specified

Web page: Not specified

University of Toronto

Country: Canada

City: Not specified

Web page: Not specified

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IMPAcTB

Hi-IMPAcTB

No description specified

Submitter: Dikshant Pradhan

Studies: CD4+ T cells are homeostasis regulators during Mtb reinfection, CD8+ lymphocytes are critical for early control of tuberculosis in macaques, Fc-FcγR interactions shift alveolar macrophage metabolism to promote Myc..., Fc-engineered antibodies leverage neutrophils to drive control of Mycoba..., Humoral correlates of protection against Mycobacterium tuberculosis foll..., Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resis..., Multi-modal data integration using Markov Field graphical networks predi..., Multimodal profiling of lung granulomas in macaques reveals cellular cor..., Mycobacterium tuberculosis-specific antibodies detect progression to act..., Robust IgM responses following intravenous vaccination with Bacille Calm..., Specific CD4+ T cell phenotypes associate with bacterial control in peop...

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Created: 14th Jan 2021 at 15:10, Last updated: 18th Oct 2021 at 14:05

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Multi-modal data integration using Markov Field graphical networks predicts B cell depletion and immune responses associated with protective intravenous BCG (IV-BCG) vaccination against tuberculosis in macaques

Hi-IMPAcTB

Shu Wang, Amy J Myers, Edward B Irvine, Chuangqi Wang, Pauline Maiello, Mark A Rodgers, Jaime Tomko, Kara Kracinovsky, H. Jacob Borish, Michael C Chao, Douaa Mugahid, Patricia A. Darrah, Robert A. Seder, Mario Roederer, Charles A Scanga, Philana Ling Lin, Galit Alter, Sarah M Fortune, JoAnne L Flynn, Douglas A Lauffenburger

Paper Link: https://doi.org/10.1101/2024.04.13.589359

Link to Model Validation Datasets: https://fairdomhub.org/studies/1198

Abstract: ...