IMPAcTB

Overview
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Web page: https://www.niaid.nih.gov/research/immune-mechanisms-protection-mycobacterium-tuberculosis

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Charles Demurjian

Projects: Hi-IMPAcTB, MIT SRP, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC)

Institutions: Massachusetts Institute of Technology

Huiming Ding

Projects: Hi-IMPAcTB, MIT SRP, MetNet

Institutions: Massachusetts Institute of Technology

Stuart Levine

Projects: MIT SRP, Hi-IMPAcTB, MetNet

Institutions: Massachusetts Institute of Technology

https://orcid.org/0000-0001-7363-562X

Francesca Licciardello

Projects: Hi-IMPAcTB, MetNet, MIT SRP

Institutions: MIT, Massachusetts Institute of Technology

Douaa Mugahid

Projects: Hi-IMPAcTB

Institutions: Massachusetts Institute of Technology

https://orcid.org/0000-0002-3455-2992

Dikshant Pradhan

Projects: Hi-IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology

Jake Schissel

Projects: Hi-IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

shuwang543

Projects: Hi-IMPAcTB

Institutions: University of Toronto

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Hi-IMPAcTB

About

This project houses all the publicly available datasets generated by the Hi-IMPAcTB consortium over the course of its 7+ years.

What is Hi-IMPAcTB?

Hi-IMPAcTB is an ambitious endeavor bringing together a team of international, interdisciplinary researchers to improve our understanding of host-pathogen interactions in the context of tuberculosis (TB). Funded by a multi-center contract from the NIH, the long-term goal of the consortium is to enable principled vaccine design by improving ...

Programme: IMPAcTB

Public web page: https://grantome.com/grant/NIH/75N93019C00071-0-9999-1

Organisms: Mus musculus, Homo sapiens, Macaca fascicularis, Macaca mulatta

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Massachusetts Institute of Technology

Country: United States

City: Not specified

Web page: Not specified

MIT

Country: United States

City: Not specified

Web page: Not specified

University of Toronto

Country: Canada

City: Not specified

Web page: Not specified

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IMPAcTB

Hi-IMPAcTB

No description specified

Submitter: Dikshant Pradhan

Studies: Age and sex influence antibody profiles associated with tuberculosis pro..., CD4+ T cells re-wire granuloma cellularity and regulatory networks to pr..., CD8+ lymphocytes are critical for early control of tuberculosis in macaques, Fc-FcγR interactions shift alveolar macrophage metabolism to promote Myc..., Fc-engineered antibodies leverage neutrophils to drive control of Mycoba..., Humoral correlates of protection against Mycobacterium tuberculosis foll..., Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resis..., Multi-modal data integration using Markov Field graphical networks predi..., Multimodal profiling of lung granulomas in macaques reveals cellular cor..., Protective intravenous BCG vaccination induces enhanced immune signaling..., Robust IgM responses following intravenous vaccination with Bacille Calm..., Specific CD4+ T cell phenotypes associate with bacterial control in peop...

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Created: 14th Jan 2021 at 15:10, Last updated: 18th Oct 2021 at 14:05

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Age and sex influence antibody profiles associated with tuberculosis progression

Hi-IMPAcTB

Leela RL Davies, Chuangqi Wang, Pia Steigler, Kathryn A Bowman, Stephanie Fischinger, Mark Hatherill, Michelle Fisher, Staney Kimbung Mbandi, Miguel Rodo, Tom HM Ottenhoff, Hazel M Dockrell, Jayne S Sutherland, Harriet Mayanja-Kizza, W Henry Boom, Gerhard Walzl, Stefan H.E. Kaufmann, Elisa Nemes, Thomas J Scriba, Douglas Lauffenburger, Galit Alter, Sarah M. Fortune.

Link to Paper: https://doi.org/10.1038/s41564-024-01678-x

Abstract: Antibody features vary ...