Programmes

The Deutsche Forschungsgemeinschaft (DFG) is the self-governing organisation for science and research in Germany. It serves all branches of science and the humanities. In organisational terms, the DFG is an association under private law. Its membership consists of German research universities, non-university research institutions, scientific associations and the Academies of Science and the Humanities.

Work of the Gygli group...

This is research programme towards the production of a collection of Chapters for a book on thermodynamics, kinetics and systems biology that is being written by Hans V. Westerhoff. This book will be a successor to 'Thermodynamics and control of biological free-energy transduction, Elsevier, Amsterdam (1987) by Westerhoff, H.V. & Van Dam, K.

This is the home programme for the Infrastructure Systems Biology @ NL activity of assisting clients with systems biology

To summarise an overview of existing evidence between Chinese medicine and polycystic ovary syndrome (PCOS)，and to evaluate the strength and validity of these associations. We retrieved systematic evaluations and meta-analyses of randomized controlled trials(RCT) evaluating Chinese herbal interventions in polycystic ovaries, including the use of decoctions or Chinese patent medicines. The quality of these systematic evaluations was evaluated using AMSTAR2 tools, while ovulation rate, pregnancy ...

Infection management requires the development of research programs that operate with the logic of network medicine for implementation of complex strategies to make the best use of availability of "omics-based" technologies, development of systems diagnostics, possibility of using innovative (and at the same time extremely expensive) drugs. This study group is composed by many experts with high knowledge in infectious diseases and “omics” competences at at Italian National Institute for Infectious ...

This page is dedicated to the bioinformatics analysis and computational modelling related to Covid-19 disease map pathways.

We develop macrophage logical models to represent the activation/polarization of this immune cell. Interactions are manually curated with available macrophage literature. The models are mainly built and analyzed in GINsim. But other resources are used to integrate specific pathways or small modules (CasQ software) and to analyze the logical models (CoLoMoTo Notebooks).

We used the Neo4j graph database approach to integrate the content of the COVID-19 Disease Map diagrams to efficiently access, query and manage the content of these diagrams and enable communication with external resources, such as Reactome and Recon, that already provide support via a similar environment.

this is personal project

Inactivation of the VHL tumor suppressor gene is linked to the development of several different tumor types in humans, including hemangioblastomas of the retina and central nervous system, clear cell renal carcinoma, pancreatic cysts, pheochromocytoma. Biochemical studies revealed that pVHL interacts with several different proteins serving as a multipurpose adaptor protein that engages in multiple protein-protein interactions to control diverse transcriptional-dependent and transcriptional-independent ...

IDPfun is an international consortium aiming to extend our knowledge on the functions of intrinsically disordered proteins (IDPs). Starting from available state of the art computational tools and databases, which have been mostly developed by IDPfun participants, it aims to drive a new level of IDP characterization.

This is a test programme, which will be used to learn how to use and evaluate Fairdom Hub for NORCE Environment's purposes, as part of the SIS-OMICS project.

nfdi4health aims to create the most comprehensive inventory of German epidemiological, public health and clinical trial data to date. It builds a centralised data catalogue with elaborate search functionalities, sophisticated data access management, and a data analysis toolbox, while respecting stringent requirements for privacy concerning personal health data. Standardisation services ensure a high degree of interoperability. Use cases covering prototypical study types and areas of research show ...

COST Action CA18133

BlueBio ERA-NET COFUND on the Blue Bioeconomy