MIT Superfund Research

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Web page: https://superfund.mit.edu/

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Dikshant Pradhan

Projects: IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology

MIT SRP

No description specified

Programme: MIT Superfund Research

Public web page: Not specified

Organisms: Not specified

Massachusetts Institute of Technology

Country: United States

City: Not specified

Web page: Not specified

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Studies: Excision of mutagenic replication-blocking lesions suppresses cancer but...

Assays: GPT Assay – Data Attached, Mass Spectrometry Processing – Data Linked, Mass Spectrometry – Data Linked, Mouse Necropsy – Metadata, RaDR Image Machine Learning Analysis – Data Attached, Tissue Imaging – Metadata, Tissue Lysis – Metadata

Snapshots: No snapshots

Created: 29th Mar 2021 at 18:33

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

MIT SRP

Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward doi: https://doi.org/10.1101/2021.01.12.426356

https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00178-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124721001789%3Fshowall%3Dtrue ...

Submitter: Dikshant Pradhan

Investigation: MIT SRP

Snapshots: Snapshot 1, Snapshot 2, Snapshot 3, Snapshot 4

DOI: 10.15490/fairdomhub.1.study.834.4

Created: 29th Mar 2021 at 18:34, Last updated: 13th Jan 2022 at 02:27

Mouse Necropsy – Metadata

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: P.ENG-200806-V2_Short-Term-Collection-at-Necrop..., P.ENG-201008-V1_Med-Term-Collection-at-Necropsy...

Data files: samples-publish2021-03-30_16-25.xlsx, samples-publish2021-03-30_17-38.xlsx, samples-publish2021-09-20_22-36.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 18:35, Last updated: 10th Jan 2022 at 17:47

Tissue Imaging – Metadata

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_16-04.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 19:57, Last updated: 10th Jan 2022 at 17:49

Mass Spectrometry – Data Linked

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_15-51.xlsx, samples-publish2021-03-30_17-07.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 20:00, Last updated: 10th Jan 2022 at 17:38

Mass Spectrometry Processing – Data Linked

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_14-31.xlsx, samples-publish2021-03-30_15-51.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 20:00, Last updated: 10th Jan 2022 at 17:37

Tissue Lysis – Metadata

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_17-07.xlsx

Snapshots: No snapshots

Created: 30th Mar 2021 at 18:57, Last updated: 10th Jan 2022 at 17:41

GPT Assay – Data Attached

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: P.ESS-201123-V1_gpt-NextGen-Protocol.pdf

Data files: 10.1016.j.celrep.2021.108864_GPT_assay, D.GPT-samples-publish2021-12-13_23-22.xlsx

Snapshots: No snapshots

Created: 20th Sep 2021 at 15:55, Last updated: 10th Jan 2022 at 17:58

RaDR Image Machine Learning Analysis – Data Attached

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: A.IMG-samples-publish2021-12-13_22-22.xlsx, WAD_RaDR_roi_extraction_10.1016.j.celrep.2021.1..., samples-publish2021-03-30_16-04.xlsx

Snapshots: No snapshots

Created: 13th Dec 2021 at 15:19, Last updated: 10th Jan 2022 at 18:04

D.GPT-samples-publish2021-12-13_23-22.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: GPT Assay – Data Attached

Download

Created: 13th Dec 2021 at 16:29

10.1016.j.celrep.2021.108864_GPT_assay.xlsx

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Download

Created: 13th Dec 2021 at 16:27

A.IMG-samples-publish2021-12-13_22-22.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: RaDR Image Machine Learning Analysis – Data Att...

Download

Created: 13th Dec 2021 at 16:08

WAD_RaDR_roi_extraction_10.1016.j.celrep.2021.108864.zip

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: RaDR Image Machine Learning Analysis – Data Att...

Download

Created: 13th Dec 2021 at 16:03

samples-publish2021-09-20_22-36.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

Download

Created: 20th Sep 2021 at 17:24

10.1016.j.celrep.2021.108864_GPT_assay

MIT SRP

GPT Assay results for "Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice" by Kay et al. https://doi.org/10.1016/j.celrep.2021.108864

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: GPT Assay – Data Attached

Download

Created: 20th Sep 2021 at 15:59

samples-publish2021-03-30_16-25.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

Created: 31st Mar 2021 at 21:11

samples-publish2021-03-30_17-38.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

Created: 31st Mar 2021 at 21:01

samples-publish2021-03-30_17-07.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mass Spectrometry – Data Linked, Tissue Lysis – Metadata

Created: 31st Mar 2021 at 20:56

samples-publish2021-03-30_16-04.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: RaDR Image Machine Learning Analysis – Data Att..., Tissue Imaging – Metadata

Created: 31st Mar 2021 at 20:44

samples-publish2021-03-30_15-51.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mass Spectrometry Processing – Data Linked, Mass Spectrometry – Data Linked

Created: 31st Mar 2021 at 20:39

samples-publish2021-03-30_14-31.xlsx

MIT SRP

Batch sample publishing

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mass Spectrometry Processing – Data Linked

Created: 31st Mar 2021 at 20:38

P.WAD-211204-V1_10.1016.j.celrep.2021.108864_RCN_parameters.txt

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Download

Created: 13th Dec 2021 at 15:58

P.ESS-201123-V1_gpt-NextGen-Protocol.pdf

MIT SRP

Next-Gen GPT Assay Protocol

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: GPT Assay – Data Attached

Download

Created: 20th Sep 2021 at 16:24

P.ENG-200806-V2_Short-Term-Collection-at-Necropsy.pdf

MIT SRP

Collection of Tissues at Necropsy of Short-Term Animals

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

Download

Created: 20th Sep 2021 at 16:19

P.ENG-201008-V1_Med-Term-Collection-at-Necropsy.pdf

MIT SRP

Medium-Term Tissue Collection at Necropsy

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

Download

Created: 20th Sep 2021 at 16:08

P.WHI-200519-V1_Bottom_up_proteomics_protocol

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 30th Mar 2021 at 19:05

P.WHI-200519-V1_Mass_spectrometry_data_processing_protocol

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 30th Mar 2021 at 18:41

P.WHI-210301-V1_Tissue_Lysis_Protocol

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

Created: 30th Mar 2021 at 18:37

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

MIT SRP

Abstract

Not specified

Authors: Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward