MIT Superfund Research

Overview
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Web page: https://superfund.mit.edu/

Funding details:

No funding details specified

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Advanced People list for this Programme with search and filtering

Charles Demurjian

Projects: IMPAcTB, MIT SRP, MetNet, Endometriosis

Institutions: Massachusetts Institute of Technology

Huiming Ding

Projects: IMPAcTB, MIT SRP, MetNet

Institutions: Massachusetts Institute of Technology

Stuart Levine

Projects: MIT SRP, IMPAcTB, MetNet

Institutions: Massachusetts Institute of Technology

https://orcid.org/0000-0001-7363-562X

Dikshant Pradhan

Projects: IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology

Jake Schissel

Projects: IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Advanced Projects list for this Programme with search and filtering

MIT SRP

No description specified

Programme: MIT Superfund Research

Public web page: Not specified

Organisms: Not specified

Advanced Institutions list for this Programme with search and filtering

Massachusetts Institute of Technology

Country: United States

City: Not specified

Web page: Not specified

Advanced Investigations list for this Programme with search and filtering

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Studies: Benthic fluxes of fluorescent dissolved organic material, salt and heat ..., Excision of mutagenic replication-blocking lesions suppresses cancer but..., Interaction of N-Nitroamines with Bincuelar Copper Complexs for Luminsec..., Molecular origins of mutational spectra produced by the environmental ca..., Novel In Vivo CometChip Reveals NDMA-Induced DNA Damage and Repair in Mu...

Assays: Absorption and Emission Spectroscopy - Data Linked, Absorption and Emission Spectroscopy Analysis - Data Linked, Chemical Challenge - Metadata, Chemical Synthesis - Metadata, Comet Chip - Data Linked, Comet Chip Analysis - Data Attached, Crystallography - Data Linked, Electron Paramagnetic Resonance - Data Linked, Extraction and Library Creation - Metadata, Field Water Sensor Run, GPT Assay - Data Attached, GPT Assay – Data Attached, Genome Alignment - Data Linked, High Resolution Mass Spectra - Data Linked, High Resolution Mass Spectra Analysis - Data Linked, Illumina Sequencing - Data Linked, Mass Spectrometry Processing – Data Linked, Mass Spectrometry – Data Linked, Mouse Necropsy – Metadata, Mutational Spectral Analysis - Data Attached, Necropsy - Metadata, Nuclear Magnetic Resonance Spectroscopy - Data Linked, Nuclear Magnetic Resonance Spectroscopy Analysis - Data Linked, RaDR Image Machine Learning Analysis – Data Attached, Tissue Collection - Metadata, Tissue Imaging – Metadata, Tissue Lysis – Metadata, X-ray Photoelectron Spectroscopy - Data Linked

Snapshots: No snapshots

Created: 29th Mar 2021 at 18:33

Advanced Studies list for this Programme with search and filtering

Novel In Vivo CometChip Reveals NDMA-Induced DNA Damage and Repair in Multiple Mouse Tissues

MIT SRP

Norah Owiti, Joshua Corrigan, Lee Pribyl, Jennifer Kay, Bevin Engelward

https://doi.org/10.3390/ijms231911776

The comet assay is a versatile assay for detecting DNA damage in eukaryotic cells. The assay can measure the levels of various types of damage, including DNA strand breaks, abasic sites and alkali-sensitive sites. Furthermore, the assay can also be modified to include purified DNA glycosylases so that alkylated and oxidized bases can be detected. The ...

Submitter: Charles Demurjian

Investigation: MIT SRP

Assays: Chemical Challenge - Metadata, Comet Chip - Data Linked, Comet Chip Analysis - Data Attached, Tissue Collection - Metadata

Snapshots: No snapshots

Created: 13th Sep 2023 at 17:58, Last updated: 13th Sep 2023 at 18:24

Benthic fluxes of fluorescent dissolved organic material, salt and heat measured by multiple-sensor aquatic eddy covariance

MIT SRP

Irene Hu and Harold Hemond

https://doi.org/10.3390/

Aquatic eddy covariance (AEC) is an in situ technique for measuring fluxes in marine and freshwater systems based on the covariance of velocity and concentration measurements. Here, development of a fast multiple-channel sensor (FACT) enables the use of AEC for measurement of benthic fluxes of fluorescent dissolved organic material, salt, and heat at three distinct sites in Massachusetts, USA, including the ...

Submitter: Huiming Ding

Investigation: MIT SRP

Assays: Field Water Sensor Run

Snapshots: Snapshot 1

DOI: 10.15490/fairdomhub.1.study.1083.1

Created: 24th Aug 2022 at 16:12, Last updated: 4th Aug 2023 at 16:01

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

MIT SRP

Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward

doi: https://doi.org/10.1101/2021.01.12.426356

Link to all of the Imaging done in this study: https://omero.mit.edu/webclient/?show=project-153 ...

Submitter: Dikshant Pradhan

Investigation: MIT SRP

Assays: GPT Assay – Data Attached, Mass Spectrometry Processing – Data Linked, Mass Spectrometry – Data Linked, Mouse Necropsy – Metadata, RaDR Image Machine Learning Analysis – Data Attached, Tissue Imaging – Metadata, Tissue Lysis – Metadata

Snapshots: Snapshot 1, Snapshot 2, Snapshot 3, Snapshot 4

DOI: 10.15490/fairdomhub.1.study.834.4

Created: 29th Mar 2021 at 18:34, Last updated: 4th Aug 2023 at 15:59

Interaction of N-Nitroamines with Bincuelar Copper Complexs for Luminsecent Detection

MIT SRP

Haosheng Feng, Shao-Xiong Lennon Luo, Robert G Croy, John M. Essigmann, Timothy M. Swager

https://doi.org/10.1039/D2DT03848J

Cu(I) from tetrakis(acetonitrile)copper(I) hexafluorophosphate ([Cu(MeCN)4]PF6) was complexed with five structurally related phosphines containing N-heterocycles. The interactions between the resulting complexes and some N-nitrosamines were studied using X-ray crystallography as well as emission spectroscopy. Upon complexation, three ...

Submitter: Charles Demurjian

Investigation: MIT SRP

Assays: Absorption and Emission Spectroscopy - Data Linked, Absorption and Emission Spectroscopy Analysis - Data Linked, Chemical Synthesis - Metadata, Crystallography - Data Linked, Electron Paramagnetic Resonance - Data Linked, High Resolution Mass Spectra - Data Linked, High Resolution Mass Spectra Analysis - Data Linked, Nuclear Magnetic Resonance Spectroscopy - Data Linked, Nuclear Magnetic Resonance Spectroscopy Analysis - Data Linked, X-ray Photoelectron Spectroscopy - Data Linked

Snapshots: Snapshot 1

Created: 24th Feb 2023 at 22:32, Last updated: 16th Mar 2023 at 18:21

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents

MIT SRP

Amanda L. Armijo, Pennapa Thongaram, Bogdan I. Fedeles, Judy Yau, Jennifer E Kay, Joshua J. Corrigan, Marisa Chancharoen, Supawadee Chawanthayatham, Leona D. Samson, Sebastian E. Carrasco, Bevin P. Engelward, James G. Fox, Robert G. Croy & John M. Essigmann

DNA-methylating environmental carcinogens such as N-nitrosodimethylamine (NDMA) and certain alkylators used in chemotherapy form O6-methylguanine (m6G) as a functionally critical intermediate. NDMA ...

Submitter: Charles Demurjian

Investigation: MIT SRP

Assays: Extraction and Library Creation - Metadata, GPT Assay - Data Attached, Genome Alignment - Data Linked, Illumina Sequencing - Data Linked, Mutational Spectral Analysis - Data Attached, Necropsy - Metadata

Snapshots: Snapshot 1

Created: 9th Feb 2023 at 22:50, Last updated: 8th Mar 2023 at 23:25

1 hidden item

Showing 20 out of a possible 28 Assays Advanced Assays list for this Programme with search and filtering

Mouse Necropsy – Metadata

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: P.ENG-200806-V2_Short-Term-Collection-at-Necrop..., P.ENG-201008-V1_Med-Term-Collection-at-Necropsy...

Data files: samples-publish2021-03-30_16-25.xlsx, samples-publish2021-03-30_17-38.xlsx, samples-publish2021-09-20_22-36.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 18:35, Last updated: 10th Jan 2022 at 17:47

Tissue Imaging – Metadata

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_16-04.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 19:57, Last updated: 10th Jan 2022 at 17:49

Mass Spectrometry – Data Linked

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_15-51.xlsx, samples-publish2021-03-30_17-07.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 20:00, Last updated: 10th Jan 2022 at 17:38

Mass Spectrometry Processing – Data Linked

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_14-31.xlsx, samples-publish2021-03-30_15-51.xlsx

Snapshots: No snapshots

Created: 29th Mar 2021 at 20:00, Last updated: 10th Jan 2022 at 17:37

Tissue Lysis – Metadata

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: samples-publish2021-03-30_17-07.xlsx

Snapshots: No snapshots

Created: 30th Mar 2021 at 18:57, Last updated: 10th Jan 2022 at 17:41

GPT Assay – Data Attached

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: P.ESS-201123-V1_gpt-NextGen-Protocol.pdf

Data files: 10.1016.j.celrep.2021.108864_GPT_assay, D.GPT-samples-publish2021-12-13_23-22.xlsx

Snapshots: No snapshots

Created: 20th Sep 2021 at 15:55, Last updated: 10th Jan 2022 at 17:58

RaDR Image Machine Learning Analysis – Data Attached

MIT SRP

No description specified

Submitter: Dikshant Pradhan

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Excision of mutagenic replication-blocking lesi...

Organisms: No organisms

SOPs: No SOPs

Data files: A.IMG-samples-publish2021-12-13_22-22.xlsx, WAD_RaDR_roi_extraction_10.1016.j.celrep.2021.1..., samples-publish2021-03-30_16-04.xlsx

Snapshots: No snapshots

Created: 13th Dec 2021 at 15:19, Last updated: 10th Jan 2022 at 18:04

Chemical Challenge - Metadata

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Novel In Vivo CometChip Reveals NDMA-Induced DN...

Organisms: No organisms

SOPs: 2 hidden items

Data files: 2 hidden items

Snapshots: No snapshots

Created: 13th Sep 2023 at 18:13, Last updated: 13th Sep 2023 at 19:15

Tissue Collection - Metadata

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Novel In Vivo CometChip Reveals NDMA-Induced DN...

Organisms: No organisms

SOPs: 2 hidden items

Data files: 2 hidden items

Snapshots: No snapshots

Created: 13th Sep 2023 at 18:14, Last updated: 13th Sep 2023 at 19:31

Comet Chip - Data Linked

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Novel In Vivo CometChip Reveals NDMA-Induced DN...

Organisms: No organisms

SOPs: 2 hidden items

Data files: 3 hidden items

Snapshots: No snapshots

Created: 13th Sep 2023 at 18:15, Last updated: 19th Sep 2023 at 20:18

Comet Chip Analysis - Data Attached

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Novel In Vivo CometChip Reveals NDMA-Induced DN...

Organisms: No organisms

SOPs: 1 hidden item

Data files: 15 hidden items

Snapshots: No snapshots

Created: 13th Sep 2023 at 18:15, Last updated: 19th Sep 2023 at 20:18

Field Water Sensor Run

MIT SRP

No description specified

Submitter: Jake Schissel

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Benthic fluxes of fluorescent dissolved organic...

Organisms: No organisms

SOPs: P.HEM-220913-V2_20210513_fieldworkOperatingProc..., P.HEM-220913-V2_20210520_fieldworkOperatingProc..., P.HEM-220913-V2_20210610_fieldworkOperatingProc...

Data files: D.SNSR-samples-publish2022-10-11_18-50.xlsx, LOC-samples-publish2022-10-11_18-37.xlsx and 3 hidden items

Snapshots: No snapshots

Created: 11th Oct 2022 at 15:51, Last updated: 18th Aug 2023 at 19:52

Necropsy - Metadata

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: No SOPs

Data files: MUS-samples-publish2023-03-08_12-23.xlsx, PAV-samples-publish2023-03-08_12-32.xlsx, TIS-samples-publish2023-03-08_12-40.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:17, Last updated: 8th Mar 2023 at 23:52

Chemical Synthesis - Metadata

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230223-V1_synthesis-protocol

Data files: CHM-samples-publish2023-03-16_10-12.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:49, Last updated: 16th Mar 2023 at 18:22

Extraction and Library Creation - Metadata

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ENG-200806-V2_Short-Term-Collection-at-Necrop..., P.ENG-200831-V1_NDMA-Juvenile-Mouse-Injection-P..., P.ENG-220105-V1_NDMA-Juvenile-Mouse-Single-Inje..., P.ENG-220105-V1_Tissue-Collection-at-Necropsy-(..., P.ESS-230303-V2_Cell-culture.docx

Data files: CEL-samples-publish2023-03-08_11-57.xlsx, DNA-samples-publish2023-03-08_13-15.xlsx, TIS-samples-publish2023-03-08_12-40.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:22, Last updated: 8th Mar 2023 at 23:52

Absorption and Emission Spectroscopy - Data Linked

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230302-V1_Fluorescence-and-XPS

Data files: CHM-samples-publish2023-03-16_10-12.xlsx, D.SPC-samples-publish2023-03-16_10-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:50, Last updated: 16th Mar 2023 at 18:22

GPT Assay - Data Attached

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ESS-201123-V1_gpt-NextGen-Protocol-.pdf

Data files: D.GPT-samples-publish2023-03-08_13-55.xlsx, DNA-samples-publish2023-03-08_13-15.xlsx, NDMA_in-vivo_gpt_data.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:24, Last updated: 8th Mar 2023 at 23:52

Absorption and Emission Spectroscopy Analysis - Data Linked

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: No SOPs

Data files: A.SPC-samples-publish2023-03-16_10-25.xlsx, D.SPC-samples-publish2023-03-16_10-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:56, Last updated: 16th Mar 2023 at 18:22

Illumina Sequencing - Data Linked

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Molecular origins of mutational spectra produce...

Organisms: No organisms

SOPs: P.ESS-230308-V2_Duplex-sequencing.docx

Data files: D.SEQ-samples-publish2023-03-24_13-17.xlsx, DNA-samples-publish2023-03-08_13-15.xlsx

Snapshots: No snapshots

Created: 7th Mar 2023 at 21:15, Last updated: 24th Mar 2023 at 19:30

Nuclear Magnetic Resonance Spectroscopy - Data Linked

MIT SRP

No description specified

Submitter: Charles Demurjian

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: MIT SRP

Study: Interaction of N-Nitroamines with Bincuelar Cop...

Organisms: No organisms

SOPs: P.SWA-230302-V1_NMR

Data files: CHM-samples-publish2023-03-16_10-12.xlsx, D.NMR-samples-publish2023-03-16_11-23.xlsx

Snapshots: No snapshots

Created: 16th Mar 2023 at 15:52, Last updated: 16th Mar 2023 at 18:22

View all 28 Assays

Showing 20 out of a possible 37 Data files Advanced Data files list for this Programme with search and filtering

D.SEQ-samples-publish2023-03-24_13-17.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Genome Alignment - Data Linked, Illumina Sequencing - Data Linked

Download

Created: 24th Mar 2023 at 19:30, Last updated: 24th Mar 2023 at 20:12

Views: 204, Downloads: 1

A.ALN-samples-publish2023-03-24_14-05.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Genome Alignment - Data Linked

Download

Created: 24th Mar 2023 at 20:07, Last updated: 24th Mar 2023 at 20:12

Views: 213, Downloads: 1

A.MSP-samples-publish2023-03-16_11-37.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra Analysis - Data Li...

Download

Created: 16th Mar 2023 at 17:44, Last updated: 16th Mar 2023 at 18:23

Views: 202, Downloads: 1

A.SPC-samples-publish2023-03-16_10-25.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy Analysis -...

Download

Created: 16th Mar 2023 at 17:17, Last updated: 16th Mar 2023 at 18:23

Views: 225, Downloads: 2

A.NMR-samples-publish2023-03-16_11-39.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Nuclear Magnetic Resonance Spectroscopy Analysi...

Download

Created: 16th Mar 2023 at 17:40, Last updated: 16th Mar 2023 at 18:23

Views: 200, Downloads: 0

D.PRM-samples-publish2023-03-16_11-48.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Electron Paramagnetic Resonance - Data Linked

Download

Created: 16th Mar 2023 at 17:55, Last updated: 16th Mar 2023 at 18:23

Views: 285, Downloads: 1

D.XRS-samples-publish2023-03-16_11-57.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: X-ray Photoelectron Spectroscopy - Data Linked

Download

Created: 16th Mar 2023 at 17:58, Last updated: 16th Mar 2023 at 18:23

Views: 217, Downloads: 0

D.NMR-samples-publish2023-03-16_11-23.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Nuclear Magnetic Resonance Spectroscopy - Data ..., Nuclear Magnetic Resonance Spectroscopy Analysi...

Download

Created: 16th Mar 2023 at 17:29, Last updated: 16th Mar 2023 at 18:22

Views: 197, Downloads: 1

D.MSP-samples-publish2023-03-16_11-35.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra - Data Linked, High Resolution Mass Spectra Analysis - Data Li...

Download

Created: 16th Mar 2023 at 17:43, Last updated: 16th Mar 2023 at 18:22

Views: 206, Downloads: 2

D.CRY-samples-publish2023-03-16_11-47.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Crystallography - Data Linked

Download

Created: 16th Mar 2023 at 17:54, Last updated: 16th Mar 2023 at 18:22

Views: 209, Downloads: 1

CHM-samples-publish2023-03-16_10-12.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy - Data Linked, Chemical Synthesis - Metadata, Crystallography - Data Linked, Electron Paramagnetic Resonance - Data Linked, High Resolution Mass Spectra - Data Linked, Nuclear Magnetic Resonance Spectroscopy - Data ..., X-ray Photoelectron Spectroscopy - Data Linked

Download

Created: 16th Mar 2023 at 16:20, Last updated: 16th Mar 2023 at 18:22

Views: 194, Downloads: 1

D.SPC-samples-publish2023-03-16_10-23.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy - Data Linked, Absorption and Emission Spectroscopy Analysis -...

Download

Created: 16th Mar 2023 at 17:15, Last updated: 16th Mar 2023 at 18:22

Views: 194, Downloads: 1

DNA-samples-publish2023-03-08_13-15.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

Download

Created: 8th Mar 2023 at 19:23, Last updated: 8th Mar 2023 at 23:52

Views: 233, Downloads: 0

NDMA_in-vivo_gpt_data.xlsx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

Download

Created: 8th Mar 2023 at 19:50, Last updated: 8th Mar 2023 at 23:52

Views: 179, Downloads: 1

D.GPT-samples-publish2023-03-08_13-55.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

Download

Created: 8th Mar 2023 at 20:07, Last updated: 8th Mar 2023 at 23:52

Views: 189, Downloads: 3

Armijo-NDMA_HRMS-data.xlsx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Mutational Spectral Analysis - Data Attached

Download

Created: 8th Mar 2023 at 23:46, Last updated: 8th Mar 2023 at 23:52

Views: 276, Downloads: 1

A.MUSP-samples-publish2023-03-08_17-46.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Mutational Spectral Analysis - Data Attached

Download

Created: 8th Mar 2023 at 23:49, Last updated: 8th Mar 2023 at 23:52

Views: 205, Downloads: 2

CEL-samples-publish2023-03-08_11-57.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

Download

Created: 8th Mar 2023 at 18:17, Last updated: 8th Mar 2023 at 23:52

Views: 177, Downloads: 1

TIS-samples-publish2023-03-08_12-40.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata, Necropsy - Metadata

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Created: 8th Mar 2023 at 19:11, Last updated: 8th Mar 2023 at 23:52

Views: 202, Downloads: 1

DNA-samples-publish2023-03-08_13-15.xlsx

MIT SRP

Batch sample publishing

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 19:20, Last updated: 8th Mar 2023 at 23:52

Views: 168, Downloads: 0

22 hidden items

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Showing 20 out of a possible 23 SOPs Advanced SOPs list for this Programme with search and filtering

P.SWA-230302-V1_Jeol-Accu-ToF_05252022

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra - Data Linked

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Created: 16th Mar 2023 at 18:16, Last updated: 16th Mar 2023 at 18:24

Views: 226, Downloads: 1

P.SWA-230223-V1_synthesis-protocol

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Chemical Synthesis - Metadata

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Created: 16th Mar 2023 at 18:13, Last updated: 16th Mar 2023 at 18:23

Views: 224, Downloads: 3

P.SWA-230302-V1_Fluorescence-and-XPS

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Absorption and Emission Spectroscopy - Data Linked, X-ray Photoelectron Spectroscopy - Data Linked

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Created: 16th Mar 2023 at 18:14, Last updated: 16th Mar 2023 at 18:23

Views: 258, Downloads: 2

P.SWA-230302-V1_Mass-Spectrometry

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: High Resolution Mass Spectra - Data Linked

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Created: 16th Mar 2023 at 18:15, Last updated: 16th Mar 2023 at 18:23

Views: 236, Downloads: 2

P.SWA-230302-V1_NMR

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Interaction of N-Nitroamines with Bincuelar Cop...

Assays: Nuclear Magnetic Resonance Spectroscopy - Data ...

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Created: 16th Mar 2023 at 18:17, Last updated: 16th Mar 2023 at 18:23

Views: 218, Downloads: 1

P.ESS-201123-V1_gpt-NextGen-Protocol-.pdf

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: GPT Assay - Data Attached

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Created: 8th Mar 2023 at 20:27, Last updated: 8th Mar 2023 at 23:52

Views: 179, Downloads: 0

P.ESS-230303-V1_Data-processing-(alignment).docx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Genome Alignment - Data Linked, Mutational Spectral Analysis - Data Attached

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Created: 8th Mar 2023 at 20:32, Last updated: 8th Mar 2023 at 23:52

Views: 195, Downloads: 1

P.ESS-230303-V2_Cell-culture.docx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:28, Last updated: 8th Mar 2023 at 23:52

Views: 225, Downloads: 1

P.ESS-230308-V2_Duplex-sequencing.docx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Illumina Sequencing - Data Linked

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Created: 8th Mar 2023 at 20:30, Last updated: 8th Mar 2023 at 23:52

Views: 186, Downloads: 0

P.ENG-200831-V1_NDMA-Juvenile-Mouse-Injection-Protocol.pdf

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:35, Last updated: 8th Mar 2023 at 23:52

Views: 190, Downloads: 0

P.ENG-200806-V2_Short-Term-Collection-at-Necropsy.pdf

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:35, Last updated: 8th Mar 2023 at 23:52

Views: 216, Downloads: 0

P.ENG-220105-V1_NDMA-Juvenile-Mouse-Single-Injection-Protocol.docx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:36, Last updated: 8th Mar 2023 at 23:52

Views: 187, Downloads: 0

P.ENG-220105-V1_Tissue-Collection-at-Necropsy-(2021).docx

MIT SRP

No description specified

Creator: Charles Demurjian

Submitter: Charles Demurjian

Investigations: MIT SRP

Studies: Molecular origins of mutational spectra produce...

Assays: Extraction and Library Creation - Metadata

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Created: 8th Mar 2023 at 20:37, Last updated: 8th Mar 2023 at 23:52

Views: 190, Downloads: 0

P.HEM-220913-V2_20210610_fieldworkOperatingProc.docx

MIT SRP

No description specified

Creator: Jake Schissel

Submitter: Jake Schissel

Investigations: MIT SRP

Studies: Benthic fluxes of fluorescent dissolved organic...

Assays: Field Water Sensor Run

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Created: 11th Oct 2022 at 15:57, Last updated: 17th Oct 2022 at 21:23

Views: 328, Downloads: 4

P.HEM-220913-V2_20210520_fieldworkOperatingProc.docx

MIT SRP

No description specified

Creator: Jake Schissel

Submitter: Jake Schissel

Investigations: MIT SRP

Studies: Benthic fluxes of fluorescent dissolved organic...

Assays: Field Water Sensor Run

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Created: 11th Oct 2022 at 15:56, Last updated: 17th Oct 2022 at 21:23

Views: 290, Downloads: 3

P.HEM-220913-V2_20210513_fieldworkOperatingProc.docx

MIT SRP

No description specified

Creator: Jake Schissel

Submitter: Jake Schissel

Investigations: MIT SRP

Studies: Benthic fluxes of fluorescent dissolved organic...

Assays: Field Water Sensor Run

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Created: 11th Oct 2022 at 15:55, Last updated: 17th Oct 2022 at 21:23

Views: 298, Downloads: 5

P.WAD-211204-V1_10.1016.j.celrep.2021.108864_RCN_parameters.txt

MIT SRP

No description specified

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: No Investigations

Studies: No Studies

Assays: No Assays

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Created: 13th Dec 2021 at 15:58

Views: 464, Downloads: 4

P.ESS-201123-V1_gpt-NextGen-Protocol.pdf

MIT SRP

Next-Gen GPT Assay Protocol

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: GPT Assay – Data Attached

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Created: 20th Sep 2021 at 16:24

Views: 662, Downloads: 13

P.ENG-200806-V2_Short-Term-Collection-at-Necropsy.pdf

MIT SRP

Collection of Tissues at Necropsy of Short-Term Animals

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

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Created: 20th Sep 2021 at 16:19

Views: 656, Downloads: 12

P.ENG-201008-V1_Med-Term-Collection-at-Necropsy.pdf

MIT SRP

Medium-Term Tissue Collection at Necropsy

Creator: Dikshant Pradhan

Submitter: Dikshant Pradhan

Investigations: MIT SRP

Studies: Excision of mutagenic replication-blocking lesi...

Assays: Mouse Necropsy – Metadata

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Created: 20th Sep 2021 at 16:08

Views: 693, Downloads: 11

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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

MIT SRP

Abstract

Not specified

Authors: Jennifer E. Kay, Joshua J. Corrigan, Amanda L. Armijo, Ilana S. Nazari, Ishwar N. Kohale, Dorothea K. Torous, Svetlana L. Avlasevich, Robert G. Croy, Dushan N. Wadduwage, Sebastian E. Carrasco, Stephen D. Dertinger, Forest M. White, John M. Essigmann, Leona D. Samson, Bevin P. Engelward