This is research programme towards the production of a collection of Chapters for a book on thermodynamics, kinetics and systems biology that is being written by Hans V. Westerhoff. This book will be a successor to 'Thermodynamics and control of biological free-energy transduction, Elsevier, Amsterdam (1987) by Westerhoff, H.V. & Van Dam, K.
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Projects: SysMO-LAB, MOSES, PSYSMO, SulfoSys, SulfoSys - Biotec, EraCoBiotech 2 nd call proposal preparation, Make Me My Model, Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population, Modelling COVID-19 epidemics, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation, Xenophiles Systems Biology, Thermodynamics, Non equilibrium thermodynamics, Book on Thermodynamics, and kinetics, Teaching Alien Biology, Outdated material, Fusion-fission-mitophagyhttps://orcid.org/0000-0002-0443-6114
Systems Biologist at University of Amsterdam, Free University Amsterdam, University of Manchester, Infrastructure Systems Biology.NL (ISBE.NL), Systems Biology Amsterdam.
Chapter on non equilibrium thermodynamics. The chapter discusses both phenomenological and mechanistic non equilibrium thermodynamics. The phenomenological part has as asset compared to earlier treatments that it also considers the phenomenological stoichiometry as a parameter that may be adjusted by systems to attain optimal performance. In the mechanistic part, this feature of variable stoichiometry and 'slips' as well as redistribution of fluxes over parallel branches of metabolism is discussed. ...
A chapter on generalized thermodynamics. The chapter is not specifically about biology although it uses many examples in biology due to the richness of the topic. It deals with the first and second law of thermodynamics, catalysts, and engines. This includes heat engines, heat pumps, and protonmotive ATP synthase.
Westerhoff H.V. and Van Dam K. (1987) Thermodynamics and control of biological free-energy transduction, Elsevier, Amsterdam ISBN: 0-444-80783-7 (U.S.)
This monograph gives the basis of both non equilibrium thermodynamics and metabolic control analysis in biology. It is rife with examples from bioenergetics.
It is also a compilation of mathematical equations and text and hence serves as a data file for mathematical biology and biological modelling
Creator: Hans V. Westerhoff
Submitter: Hans V. Westerhoff
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Studies: No Studies
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In this short book written by Hans V. Westerhoff, it is argued that scientific rationality as further developed in systems biology should be used to tackle the complex problems of society. This is promoted as one way to battle the disinformation strategies followed by a great many political leaders with the aim of staying in power through populism.
To be cited as: Westerhoff, H.V., (2020) Trumping the Trumps: Addressing complexities through biological rationality, SysBA press, Amsterdam.