Systems analysis of process-induced stresses: towards a quantum increase in process performance of Pseudomonas putida as the cell factory of choice for white biotechnology.
The specific goal of this project is to exploit the full biotechnological efficacy of Pseudomonas putida KT2440 by developing new optimization strategies that increase its performance through a systems biology understanding of key metabolic and regulatory parameters that control callular responses to key stresses generated during biotechnological application of this versatile bacterium.
Programme: SysMO
SEEK ID: https://fairdomhub.org/projects/6
Public web page: http://www.psysmo.org/
Organisms: Pseudomonas putida
FAIRDOM PALs: Carolyn Lam, Paul McDermott
Project created: 15th Jan 2009
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Projects: PSYSMO
Institutions: Helmholtz Centre for Infection Research Braunschweig
Projects: PSYSMO
Institutions: Queen's University Belfast
Projects: PSYSMO
Institutions: University of Dortmund
Projects: PSYSMO
Institutions: University of Dortmund
Projects: PSYSMO
Institutions: Helmholtz Centre for Infection Research Braunschweig
Expertise: functional protein expression, protein-protein interactions, Microbiology/ Protein chemistry/ Molecular biology, genetic engineering
Tools: Mass spectrometry, Proteomics (2D-PAGE), protein interaction studies, in vivo crosslinking, affinity copurification/precipitation, model prediction testing
Projects: PSYSMO, EmPowerPutida, SynBio4Flav
Institutions: CSIC Madrid, CSIC
Projects: PSYSMO
Institutions: CSIC Madrid
Projects: PSYSMO
Institutions: CSIC Madrid
Projects: PSYSMO
Institutions: CSIC Madrid
Projects: PSYSMO
Institutions: CSIC Madrid
Projects: PSYSMO
Institutions: University of Hannover
Projects: PSYSMO
Institutions: University of Duesseldorf
Projects: PSYSMO
Institutions: University of Braunschweig
Projects: PSYSMO
Institutions: Queen's University Belfast
Projects: PSYSMO
Institutions: University of Braunschweig
Projects: PSYSMO
Institutions: University of Duesseldorf
Projects: PSYSMO
Institutions: University of Braunschweig
Projects: PSYSMO
Institutions: Imperial College London
Projects: PSYSMO
Institutions: University of Hannover
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Abstract (Expand)
Authors: , I. F. Escapa, C. Jager, J. Puchalka, , , ,
Date Published: 20th Mar 2012
Publication Type: Not specified
PubMed ID: 22433058
Citation:
Abstract (Expand)
Authors: , F. Schmidt, , C. F. Davenport, M. Gesell Salazar, U. Volker,
Date Published: 1st Mar 2011
Publication Type: Not specified
PubMed ID: 21306427
Citation:
Abstract (Expand)
Authors: , , P. Hagendorf, R. Geffers, U. Schock, T. Pohl, C. F. Davenport,
Date Published: 28th Feb 2011
Publication Type: Not specified
PubMed ID: 21355971
Citation:
Abstract (Expand)
Authors: M. Carmen Herrera, , José J. RodrÃguez-Herva, Ana M. Fernández-Escamilla,
Date Published: 2010
Publication Type: Not specified
DOI: 10.1111/j.1462-2920.2009.02124.x
Citation:
Abstract (Expand)
Authors: Vanina García, Patricia Godoy, Craig Daniels, Ana Hurtado, , Ana Segura
Date Published: 1st Nov 2009
Publication Type: Not specified
DOI: 10.1111/j.1758-2229.2009.00093.x
Citation:
Abstract (Expand)
Authors: Jacek Puchałka, Matthew A Oberhardt, Miguel Godinho, Agata Bielecka, Daniela Regenhardt, , Jason A Papin,
Date Published: 27th Mar 2008
Publication Type: Not specified
PubMed ID: 18974823
Citation: