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Projects: SulfoSys - Biotec
Institutions: University of Braunschweig
Projects: SulfoSys
Institutions: University of Braunschweig
Expertise: Metabolomics
Projects: PSYSMO
Institutions: University of Braunschweig
Projects: PSYSMO
Institutions: University of Braunschweig
Projects: PSYSMO
Institutions: University of Braunschweig
Projects: BaCell-SysMO
Institutions: University of Braunschweig
Projects: PSYSMO
Institutions: University of Braunschweig
Expertise: Microbiology, Molecular Biology, Transcriptomics, Anaerobic Microbiology, Bacterial metabolism | Metabolic engineering, Regulatory Networks
Tools: Genetics, Molecular Biology, Genetic modification, Microarray analysis, Proteomics (2D-PAGE), time lapse microscopy, Molecular biology techniques (RNA/DNA/Protein), qRT-PCR
Projects: SulfoSys, PSYSMO, SulfoSys - Biotec
Institutions: University of Braunschweig
Projects: SulfoSys - Biotec
Institutions: University of Braunschweig
Expertise: enzymes, enzyme classification
Projects: PSYSMO, SulfoSys, SulfoSys - Biotec
Institutions: University of Braunschweig
Projects: SulfoSys - Biotec
Institutions: University of Braunschweig
Roles: PhD Student
Expertise: Metabolic Models
Tools: Flux balance analysis, In silico Metabolic Network Analysis, metabolic network visualization
Projects: SulfoSys
Institutions: University of Braunschweig
Expertise: Metabolomics
Projects: BaCell-SysMO
Institutions: University of Braunschweig
University Education: 1987-1993, Biotechnology (Diploma), Technische Universität Braunschweig, Germany.
Dissertation: 1993-1996, Disseration German Research Centre for Biotechnology, Biochemical Engineering Division, Braunschweig, Germany.
Habiliation: 2006, Saarland University, Saarbrücken, Germany.
Positions
1993-1996: Research Assistant, German Research Centre for Biotechnology, Biochemical Engineering Division, Braunschweig, Germany.
1997-1998: Post-doc at Department of Applied Chemistry &
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Projects: SulfoSys - Biotec
Institutions: University of Braunschweig
Expertise: Metabolomics
Within the e:Bio - Innovationswettbewerb Systembiologie (Federal Ministry of Education and Research (BMBF)), the SulfoSYSBIOTECH consortium (10 partners), aim to unravel the complexity and regulation of the carbon metabolic network of the thermoacidophilic archaeon Sulfolobus solfataricus (optimal growth at 80°C and pH 3) in order to provide new catalysts ‘extremozymes’ for utilization in White Biotechnology.
Based on the available S. solfataricus genome scale metabolic model (Ulas et al., 2012)
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Programme: e:Bio
Public web page: http://www.sulfosys.com/
Organisms: Sulfolobus solfataricus
BaCell-SysMO 2
Modelling carbon core metabolism in Bacillus subtilis – Exploring the contribution of protein complexes in core carbon and nitrogen metabolism.
Bacillus subtilis is a prime model organism for systems biology approaches because it is one of the most advanced models for functional genomics. Furthermore, comprehensive information on cell and molecular biology, physiology and genetics is available and the European Bacillus community (BACELL) has a well-established reputation for applying
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Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=53
Organisms: Bacillus subtilis
Systems analysis of process-induced stresses: towards a quantum increase in process performance of Pseudomonas putida as the cell factory of choice for white biotechnology.
The specific goal of this project is to exploit the full biotechnological efficacy of Pseudomonas putida KT2440 by developing new optimization strategies that increase its performance through a systems biology understanding of key metabolic and regulatory parameters that control callular responses to key stresses generated
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Programme: SysMO
Public web page: http://www.psysmo.org/
Organisms: Pseudomonas putida
Silicon cell model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation
Programme: SysMO
Public web page: http://sulfosys.com/
Organisms: Sulfolobus solfataricus