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The project addresses the generation and establishment of programmed pacemaker cells for an in vitro drug testing possibility to perform predictive tests. This may lead to an improved treatment of cardiac arrhythmias or an accurate identification of potential drug molecules at a very early stage of development. Important benefits will arise in verifying the safety of a wide variety of medicines while reducing animal testing.
This project is funded by the European Social Fund (ESF) program of the European Union (ESF/14-BM-A55-0027).
Programme: Independent Projects
SEEK ID: https://fairdomhub.org/projects/28
Public web page: Not specified
Organisms: Homo sapiens, Mus musculus
FAIRDOM PALs: No PALs for this Project
Project created: 15th Sep 2015
Related items
- People (13)
- Institutions (4)
- Investigations (0+4)
- Studies (0+8)
- Assays (0+13)
- Data files (0+21)
- SOPs (0+9)
- Presentations (0+3)
- Events (0+2)
- Documents (0+15)
Projects: iRhythmics
Institutions: Rostock University Medical Centre
Projects: iRhythmics
Institutions: Leibniz Institute for Farm Animal Biology (FBN)

Projects: iRhythmics
Institutions: University of Rostock
Roles: Student
Expertise: Machine Learning, Deep Learning
Projects: iRhythmics
Institutions: Leibniz Institute for Farm Animal Biology (FBN)

Projects: iRhythmics
Institutions: Rostock University Medical Centre
Roles: PhD Student
Expertise: Cell biology, Molecular microbiology
Tools: Cell and tissue culture, Cytometry and fluorescent microscopy, electrophysiology
Projects: iRhythmics
Institutions: Rostock University Medical Centre
Roles: Postdoc
Expertise: Cell biology, Image analysis
Tools: super resolution microscopy, iPSC culture, Photoactivated localization microscopy
Projects: iRhythmics
Institutions: Rostock University Medical Centre
Projects: iRhythmics
Institutions: Rostock University Medical Centre
Projects: SYSTERACT, Kinetics on the move - Workshop 2016, BESTER, iRhythmics, GB-XMap: Assessing the risk of gut-brain cross-diseases Investigating the gut-brain-axis
Institutions: University of Rostock

Roles: Postdoc
Expertise: genome-scale modeling, Kinetic modelling, metabolic networks, metabolic systems biology
Tools: Matlab, Data integration, Copasi, COBRA toolbox, Cytoscape, R
Projects: iRhythmics
Institutions: Rostock University Medical Centre

Projects: iRhythmics
Institutions: University Medicine of Greifswald
Projects: iRhythmics, GB-XMap: Assessing the risk of gut-brain cross-diseases Investigating the gut-brain-axis
Institutions: University of Rostock

Roles: PhD Student
Expertise: AI, Bioinformatics, RNA-Seq, Data integration, Transcriptomics
Projects: COSMIC, BaCell-SysMO, SYSTERACT, HUMET Startup, INCOME, BESTER, iRhythmics
Institutions: University of Rostock
Expertise: Data analysis Mathematical modelling Bioinformatics Systems biology, dynamics of biological networks, dynamics and control of biological networks
Tools: quantitative western blot analysis, Stochastic models, quantitative western blot analyses, differential algebraic equations, stimulus response experiments, Mathematica, Matlab, ODE, Computational and theoretical biology