Comparison of 2D and 3D fluorescence image analysis
Here, we conduct a proof of principle by comparing a 2D and 3D fluorescent image analysis based approach on unlabeled cardiomyocytes. Based on the CellProfiler software, we extracted high-dimensional features of individual cells and nuclei, which are subsequently down-sampled and clustered. These clusters are furthermore benchmarked via different machine learning classifiers (e.g., AdaBoost, Gradient Boosting, Random Forest) as the ground truth for our proposed approach.
SEEK ID: https://fairdomhub.org/assays/1367
Modelling Analysis
Projects: iRhythmics
Investigation: hidden item
Study: hidden item
Biological problem addressed: Model Analysis Type
Organisms: No organisms
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Created: 16th Oct 2020 at 12:55
Last updated: 16th Oct 2020 at 14:28
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Projects: iRhythmics
Institutions: University of Rostock
Projects: iRhythmics
Institutions: Rostock University Medical Centre
https://orcid.org/0000-0002-1887-4772
Projects that do not fall under current programmes.
Projects: Manchester Institute for Biotechnology, ICYSB 2015 - International Practical Course in Systems Biology, iRhythmics, INBioPharm, EmPowerPutida, Systo models, MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, Multiscale modelling of state transitions in the host-microbiome-brain network, Extremophiles metabolsim, NAD COMPARTMENTATION, Agro-ecological modelling, Bergen(Ziegler lab) project AF-NADase, NAMPT affinity, Stress granules, Modelling COVID-19 epidemics
Web page: Not specified
The project addresses the generation and establishment of programmed pacemaker cells for an in vitro drug testing possibility to perform predictive tests. This may lead to an improved treatment of cardiac arrhythmias or an accurate identification of potential drug molecules at a very early stage of development. Important benefits will arise in verifying the safety of a wide variety of medicines while reducing animal testing. For more information you may visit our project website at ...
Programme: Independent Projects
Public web page: https://irhythmics.med.uni-rostock.de/
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
A CellProfiler pipeline for 3D analysis of cardiomyocytes
Creator: Maximilian Hillemanns
Submitter: Maximilian Hillemanns
