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Web page: http://www.uni-rostock.de
Country: Germany
City: Rostock
Address:
University of Rostock
18051 Rostock
Germany
Related items
Projects: FAIRDOM & LiSyM & de.NBI Data Structuring Training
Institutions: University of Rostock
Projects: COSMIC
Institutions: University of Rostock
Prof. Dr. Hubert Bahl
Head, Division of Microbiology, Institute of Biological Sciences
University of Rostock
Albert-Einstein-Str. 3
D-18051 Rostock
Projects: Sustainable co-production
Institutions: University of Rostock
Projects: SysMO-LAB
Institutions: University of Rostock
Postdoc @ Institute of Medical Microbiology, University of Rostock
Projects: COSMIC
Institutions: University of Rostock
Projects: INCOME
Institutions: University of Rostock
Projects: COVID-19 Disease Map
Institutions: University of Rostock
Expertise: Curation
Projects: COSMIC
Institutions: University of Rostock
biomathematician, PhD student at the University of Rostock, Systems Biology Group Rostock
Projects: de.NBI-SysBio, Kinetics on the move - Workshop 2016, Example use cases
Institutions: Heidelberg Institute for Theoretical Studies (HITS gGmbH), University of Rostock
Expertise: Data Management, Databases
Tools: MySQL, Java, graphdatabase, Neo4J
Projects: SysMO-LAB
Institutions: University of Rostock
Expertise: Molecular microbiology
Tools: Biochemistry and protein analysis, Genetic modification, Metabolomics
Projects: iRhythmics
Institutions: University of Rostock
Roles: PhD Student
Expertise: Machine Learning, Deep Learning
Projects: COVID-19 Disease Map
Institutions: University of Rostock

Projects: COSMIC
Institutions: University of Rostock
Roles: Postdoc
Expertise: Microbiology, Biotechnology
Tools: Transcriptomics, Fermentation, Proteomics (2D-PAGE), Gaschromatographic analysis
PhD
University of Rostock, Germany
Institute of Biological Sciences
Division of Microbiology
Albert-Einstein-Str. 3
18051 Rostock
Projects: SysMO-LAB
Institutions: University of Rostock
PD Dr. rer. nat. habil. Bernd Kreikemeyer
is the head of a research group at the Inst. of Medical Microbiology and Hospital Hygiene focusing on the pathogenesis of the human LAB Streptococcus pyogenes, microbial biofilm biology, and oral microbiology. Streptococcus pyogenes research, which is the relevant part for this BMBF proposal, is focused on 1. Identification of GAS virulence factors, 2. Mechanisms of GAS host cell adherence, host cell internalization, cytotoxicity of GAS towards host cells
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Projects: BaCell-SysMO
Institutions: University of Rostock
Expertise: Mathematical modelling, Bacillus subtilis, Deterministic modelling of gene regulation networks, stress responses, Systems Biology, sensitivity analysis, Dynamics and Control of Biological Networks, Parameter estimation
Tools: Biochemistry, Computational and theoretical biology, ODE, Matlab, linux, Stochastic models, Deterministic models, Dynamic modelling
Modelling of the general stress response activation cascade of sigB in B. subtilis in response to starvation.
Projects: COSMIC, BaCell-SysMO
Institutions: University of Rostock
Roles: Postdoc
Expertise: Mathematical modelling, dynamics of biological networks, Physics, bistability, Systems Biology, Data analysis, Statistical Physics, Dynamics and Control of Biological Networks
Tools: Computational and theoretical biology, ODE, Matlab, Mathematica, differential algebraic equations, Stochastic models, C programming, Computational Systems Biology, Dynamic modelling, Data Modelling
Modelling of cellular signalling, Dynamic Motifs and Feedback, Quantitative Measures, Theoretical Aspects of Modelling Biological Systems
Projects: COVID-19 Disease Map
Institutions: University of Rostock
Projects: SysMO-LAB
Institutions: University of Rostock
Expertise: Microbiology, Molecular microbiology
The project addresses the generation and establishment of programmed pacemaker cells for an in vitro drug testing possibility to perform predictive tests. This may lead to an improved treatment of cardiac arrhythmias or an accurate identification of potential drug molecules at a very early stage of development. Important benefits will arise in verifying the safety of a wide variety of medicines while reducing animal testing. For more information you may visit our project website at
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Programme: Independent Projects
Public web page: https://irhythmics.med.uni-rostock.de/
Organisms: Homo sapiens, Mus musculus
Here we share resources and best practices to develop a disease map for COVID-19. The project is progressing as a broad community-driven effort. We aim to establish a knowledge repository on virus-host interaction mechanisms specific to the SARS-CoV-2. The COVID-19 Disease Map is an assembly of molecular interaction diagrams established based on literature evidence.
Programme: Disease Maps
Public web page: http://doi.org/10.17881/covid19-disease-map
The project "INtegrative COllaborative modeling in systems MEdicine" aims at connecting different heterogenous datasets and individual models within systems medicine.
Programme: e:med
Public web page: Not specified
Organisms: Homo sapiens
Salmon farmed on modern feeds contains less of the healthy, long-chain fatty acids (EPA and DHA) than before. Up until the turn of the millennium, farmed salmon were fed fish oil as a replacement for their omega-3 rich natural prey. However, fish oil is now a scarce resource, and more than half of the fat in modern feeds comes from plant oils that are inexpensive, but devoid of long-chain omega-3 fatty acids. How can we increase the omega-3 content of salmon on sustainable feeds?
One option is
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Programme: The Digital Salmon
Public web page: http://tinyurl.com/genosysfat
Organisms: Danio rerio, Salmo salar, Oncorhynchus mykiss
Programme: COMBINE (Computational Modeling in Biology Network)
Public web page: https://multicellml.org/
Organisms: Not specified
Sustainable co-production is the short form of the research project “Tobacco as sustainable production platform of the natural biopolymer cyanophycin as co-product to oil and protein”. It combines plant and industrial biotechnology to increase the value of commercially grown tobacco with products that can sustainably substitute fossil raw materials. We aim to establish a new economically feasible production system for the biopolymer cyanophycin (CGP) as a by-product of tobacco without relevant
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Programme: Era CoBioTech
Public web page: Not specified
Organisms: Not specified
Bioprocesses for the optimized, integrated production of butyl esters from sustainable resources (BESTER)
Industrial Biotechnology is a key enabling technology to produce a plethora of different bio-based products from sustainable resources and a driver for developing the bio-based economy in Europe. Systems biology and Synthetic biology are recent additions to the biotechnology toolbox that in interplay with bioprocess and chemical process technology can help developing competitive industrial
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Programme: Era CoBioTech
Public web page: https://www.cobiotech.eu/call-information
Organisms: Clostridia Sp.
The gut–brain axis (GBA) provides a bidirectional homeostatic communication between the gastrointestinal tract and the central nervous system. The interdisciplinary collaboration is going to fully explore a first comprehensive GBA cross-disease map of genetic, expression and regulatory changes associated with ulcerative colitis and schizophrenia disease entities.
Dysfunction of this axis can have pathophysiological consequences. Genome-wide association studies (GWAS) have identified >300
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Programme: This Project is not associated with a Programme
Public web page: https://www.sbi.uni-rostock.de/research/projects/detail/49
Start date: 1st Feb 2019
End date: 12th Feb 2019
Organisms: Not specified
There is an urgent need for novel antibiotics to fight life-threatening infections and to counteract the increasing problem of propagating antibiotic resistance. Recently, new molecular genetic and biochemical tools have provided insight into the enormous unexploited genetic pool of environmental microbial biodiversity for new antibiotic compounds. New tools for more efficiently lifting this hidden treasure are needed to strengthen competitiveness of European industry, as well as for a cost-saving
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Programme: ERASysAPP
Public web page: https://www.erasysapp.eu/calls/2nd-call/systeract
Organisms: Streptomyces coelicolor
The Systems Biology Service Center of de.NBI (de.NBI-SysBio) provides bioinformatics support and a standards-based data management for systems biology projects, with focus on the provenance of experimental results and on the reproducibility of modeling experiments, as well as high-quality curated biochemical data to modelers and experimentalists.
The node concentrates on two tools for the data management in life sciences research: SEEK, a catalogue for storage, registration and exchange of data
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Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: Not specified
Organisms: Not specified
Programme: LiSyM - Systems Medicine of the Liver
Public web page: https://www.fairdomhub.org/events/96
Organisms: Not specified
Public showcase and collection of training material
Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: http://www.denbi.de
Organisms: Not specified
The workshop focuses on the publication, curation, retrieval, and usage of kinetic data from the reaction kinetics database SABIO-RK and on the use of data in modeling. There will be experience reports from scientists who successfully used experimental data to formulate or verify biological hypotheses with the computer, and you will experience how experimental data can be used with computational models.
Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: http://www.h-its.org/event/kinetics-on-the-move/
Aim of HUMET Startup Project is to make an inventory of expertise, research goals, resources etc. of the HUMET Coaliytion of the Willing.
Programme: HUMET
Public web page: Not specified
Organisms: Homo sapiens
Comparative Systems Biology: Lactic Acid Bacteria
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=57
BaCell-SysMO 2
Modelling carbon core metabolism in Bacillus subtilis – Exploring the contribution of protein complexes in core carbon and nitrogen metabolism.
Bacillus subtilis is a prime model organism for systems biology approaches because it is one of the most advanced models for functional genomics. Furthermore, comprehensive information on cell and molecular biology, physiology and genetics is available and the European Bacillus community (BACELL) has a well-established reputation for applying
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Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=53
Organisms: Bacillus subtilis
Systems Biology of Clostridium acetobutylicum - a possible answer to dwindling crude oil reserves
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=54
Organisms: Clostridium acetobutylicum