As an Innovative Training Network (ITN) , our approach to bringing about innovation is via education. The 15 Early Stage Researchers that join our project will gain multidisciplinary and cutting-edge expertise from our hosting institutions and associated partners, which is required to manipulate biological catalysts for meeting tomorrow’s demanding challenges in sustainable production processes.
CC-TOP is focused on exploiting the potential benefits of C-C bond forming enzymes (“carboligases”) in the industrial synthesis of high value chiral compounds. We combine a multidisciplinary range of techniques and training actions to cover everything from enzyme discovery and optimisation to the design of industrial processes that allow using carboligases in real-life applications.
Building complex compounds by connecting carbon-carbon bonds is at the core of industrial organic synthesis. However, current methods often have important drawbacks, such as the use of hazardous substances or the generation of toxic waste. Our innovation is oriented to apply improved carboligases as a complementary, eco-friendly catalyst class, so that they can unleash their potential to yield the same outputs as conventional methods, but in a more efficient, selective and sustainable way.
Programme: EU Projects
SEEK ID: https://fairdomhub.org/projects/250Funding codes:
- This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 956631
Public web page: https://cc-top-itn.eu/
Organisms: No Organisms specified
FAIRDOM PALs: No PALs for this Project
Project start date: 1st Mar 2021
Project end date: 30th Mar 2024
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- Studies (0+29)
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Projects: SysMO DB, FAIRDOM, ICYSB 2015 - International Practical Course in Systems Biology, ZucAt, SysMO-LAB, Kinetics on the move - Workshop 2016, Example use cases, FAIRDOM user meeting, ErasysApp Funders, EraCoBiotech 2 nd call proposal preparation, Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW), FAIRDOM & LiSyM & de.NBI Data Structuring Training, MESI-STRAT, INCOME, Multiscale modelling of state transitions in the host-microbiome-brain network, BESTER, TRALAMINOL, Sustainable co-production, INDIE - Biotechnological production of sustainable indole, Extremophiles metabolsim, PoLiMeR - Polymers in the Liver: Metabolism and Regulation, GB-XMap: Assessing the risk of gut-brain cross-diseases Investigating the gut-brain-axis, NAD COMPARTMENTATION, HOTSOLUTE, Stress granules, FAIRDOM Community Workers, GMDS Project Group "FAIRe Dateninfrastrukturen für die Biomedizinische Informatik", Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population, COVID-19 Disease Map, AquaHealth (ERA-BlueBio), LiSyM Core Infrastructure and Management (LiSyM-PD), Early Metabolic Injury (LiSyM-EMI - Pillar I), Regeneration and Repair in Acute-on-Chronic Liver Failure (LiSyM-ACLF - Pillar III), Chronic Liver Disease Progression (LiSyM-DP - Pillar II), Liver Function Diagnostics (LiSyM-LiFuDi - Pillar IV), The Hedgehog Signalling Pathway (LiSyM-JGMMS), Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF), Model Guided Pharmacotherapy In Chronic Liver Disease (LiSyM-MGP), Molecular Steatosis - Imaging & Modeling (LiSyM-MSIM), Modelling COVID-19 epidemics, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers, SASKit: Senescence-Associated Systems diagnostics Kit for cancer and stroke, CC-TOP, BioCreative VIIhttps://orcid.org/0000-0003-3540-0402
I am a researcher at the Scientific Databases and Visualization Group at Heidelberg Institute for Theoretical Studies (HITS) , one of the developers of SabioRK - System for the Analysis of Biochemical Pathways - Reaction Kinetics (http://sabiork.h-its.org/) . I am working on design and maintenance of the information systems to store, query and analyse systems biology data; definition and implementation of methods for the integration of data from multiple sources. In SySMO-DB project ...