Andrea Rizzo

As an Innovative Training Network (ITN) , our approach to bringing about innovation is via education. The 15 Early Stage Researchers that join our project will gain multidisciplinary and cutting-edge expertise from our hosting institutions and associated partners, which is required to manipulate biological catalysts for meeting tomorrow’s demanding challenges in sustainable production processes.

CC-TOP is focused on exploiting the potential benefits of C-C bond forming enzymes (“carboligases”) ...

Time course of the aldol addition of furfural and acetone using DERA-61 in non-optimized conditions

3D structure of DERA-61 predicted by alphafold.

3D structure of DERA-61 predicted by alphafold.

Phylogenetic tree of all the 48 metagenomic DERAs in this work, with data on the expression quality of each, and the activity towards the aldol addition of furfural/benzaldehyde against acetone/butanone/cyclobutanone.

Variation of DERA-61 melting temperature in different conditions of pH, buffer type and concentration of NaCl

Kinetic of DERA-61 towards the aldol addition of furfural and acetone.