Institutions: UNIBI: Bielefeld Universityhttps://orcid.org/0000-0002-6100-9135
Projects: Millar group, TiMet, PHYTOCAL: Phytochrome Control of Resource Allocation and Growth in Arabidopsis and in Brassicaceae crops, POP - the Parameter Optimisation Problem, Regulation of flowering time in natural conditions, PlaSMo model repository
Institutions: University of Edinburghhttps://orcid.org/0000-0003-1756-3654
Projects: HUMET Startup
Institutions: Leiden University Medical Centerhttps://orcid.org/0000-0002-2172-7394
Professor in genetics and systems biology of the metabolic syndrome
Projects: HUMET Startup
Institutions: Centro de Investigación Príncipe Felipehttps://orcid.org/0000-0003-3318-120X
Tools: Databases, Genomics, Transcriptomics, Computational Systems Biology, Dynamic modelling, R, Java, Bioinformatics, Data Management, Genetics, Systems Biology, Computational and theoretical biology
My scientific interests revolve around functional genomics, systems biology and the development of algorithms and software for the analysis of high-throughput data (mainly, but not restricted to, Next Generation Sequencing) and its application to the relationship between genotype and phenotype, mainly oriented to personalized and precision medicine. I am especially interested in the study of disease mechanisms and drug action mechanisms, drug repositioning and the definition of mechanism-based
Institutions: University of Tokyo
I am a postdoc in The University of Tokyo. My research interest is to know structure of biological systems by functional relationships between genes working in response to endogenous and/or exogenous disruptions. I'm trying to find functional relationships between genes by similarity of phenotype defined with high-dimensional morphological features in yeast gene deletion collection. I'm happy if you will talk with me in any topics.
I'm an 'experimentalist' (molecular microbiologist) Postdoc working on regulation and peptide signaling in Clostridium acetobutylicum.
I'm also a SysMO-DB PAL (Product Application Liason) for COSMIC, working on data management including standards and integration with SysMO SEEK.
Tools: bacterial two-hybrid system, SubtiWiki, SPINE, Chemical cross-linking, Proteomics (2D-PAGE), mutant strain generation, Genetic modification, Genetic analysis, Biochemistry and protein analysis, Molecular Biology, Microbiology
Tools: reporter gene analyses, site-directed and random mutagenesis, plasmon resonance spectroscopy, spectroscopy, molecular biological techniques (RNA/DNA techniques), Membrane protein biochemistry, Chromatography, Fermentation, Biochemistry and protein analysis, Genetics
I am a PhD student of the microbiology department at the Ludwig-Maximilians Universität München. I work at the chair of Prof. Kirsten Jung. The topic of our workpackage deals with "K+ homeostasis in Escherichia coli". In special I'm working on the sensor kinase KdpD that controls together with the response regulator KdpE the expression of the high-affinity K+ uptake system KdpFABC. The yet not fully understood molecular mechanism of stimulus perception and signal transduction is of particular
Roles: Project Coordinator
The Veening lab is interested in phenotypic bi-stability in Streptococcus pneumoniae and its importance in virulence of this human pathogen.
I started to work with B. subtilis during my diploma thesis in Marburg, analyzing the gene expression pattern during sporulation and their control by the four sporulation sigma factors. This work was continued during my PhD thesis in Greifswald. In collaboration with Prof. Bremer and Prof. Marahiel in Marburg we also studied additional adaptation processes of B. subtilis, like the adaptation to low temperatur and high osmolarity.
I am now working as a staff scientist in Prof. Völkers lab in
Tools: transcriptional analysis (Northern blots, Molecular biology techniques (RNA/DNA), quantitative western blot analyses, Proteomics (2D-PAGE), quantitative Western analyses), molecular biological techniques (RNA/DNA techniques, Fluorescence and confocal microscopy, PCR, Web services, Pharmacology and toxicology, Spectroscopy and structural analysis, Proteomics, Genetics
Postdoctoral Research fellow with experience in Genomics, transcriptomics, proteomics and metabolomics
Expertise: fluorescence protein fusions (transcriptional and translational), localisation studies, microscopy, protein secretion, functional protein expression, gene regulation, stress responses, phenotypic heterogeneity, Bacillus subtilis, Microarray analysis, Molecular Biology, Genetics
Tools: DNA affinity chromatography, EMSA, Molecular biology techniques (RNA/DNA/Protein), transposon mutagenesis, Immunofluorescence, Fluorescence microscopy, Flow cytometry, Site-directed mutagenesis, Fluorecence based reporter gene analyses/single cell analyses, Microarray analysis, Transcriptomics, Genetic modification
PhD student. Analyzing CcpA affinity to cre boxes (catabolite responsive elements) and response of B. subtilis to membrane protein overproduction stress.
Expertise: Clostridium, carbon metabolism, bacterial metabolism, Anaerobic Microbiology, Synthetic Biology, Clostridial Genetics, Metabolic Engineering, Systems Biology, Molecular Biology, Genetics, Microbiology
I'm an experimentalist 'Pre-doc' (I still have to finish my PhD thesis) and my work on the COSMIC project will focus on setting up a metabolomic analysis method for Clostridium acetobutylicum.
In the past I have worked on metabolic engineering of the same organism by disrupting genes to asses their impact on acid and solvent formation.
I'm looking forward to joining the COSMIC web-community. It hopefully will all us to stay in touch and update each other on advances in the (computer)lab.
Projects: SysMO DB, FAIRDOM, ICYSB 2015 - International Practical Course in Systems Biology, ZucAt, SysMO-LAB, Kinetics on the move - Workshop 2016, Example use cases, FAIRDOM user meeting, ErasysApp Funders, EraCoBiotech 2 nd call proposal preparation, Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW), FAIRDOM & LiSyM & de.NBI Data Structuring Training, MESI-STRAT, INCOME, Multiscale modelling of state transitions in the host-microbiome-brain network, BESTER, TRALAMINOL, Sustainable co-production, INDIE - Biotechnological production of sustainable indole, Extremophiles metabolsim, PoLiMeR - Polymers in the Liver: Metabolism and Regulation, GB-XMap: Assessing the risk of gut-brain cross-diseases Investigating the gut-brain-axis, NAD COMPARTMENTATION, HOTSOLUTE, Stress granules, FAIRDOM Community Workers, GMDS Project Group "FAIRe Dateninfrastrukturen für die Biomedizinische Informatik"https://orcid.org/0000-0003-3540-0402
I am a researcher at the Scientific Databases and Visualization Group at Heidelberg Institute for Theoretical Studies (HITS) , one of the developers of SabioRK - System for the Analysis of Biochemical Pathways - Reaction Kinetics (http://sabiork.h-its.org/) . I am working on design and maintenance of the information systems to store, query and analyse systems biology data; definition and implementation of methods for the integration of data from multiple sources. In SySMO-DB project
Tools: Proteomics (2D-PAGE), qPCR, mutant strain generation, Northern analyses), Fluorecence based reporter gene analyses/single cell analyses, molecular biological techniques (RNA/DNA techniques, enzymatic analyses, Protein chemical methods (protein overproduction, quantitative Western analyses), purification
I am research assistant in the microbiology department at the Ludwig-Maximilians Universität in Munich (München), working at the chair of Prof. Kirsten Jung. In our SysMO consortium we generate biological data and work in close cooperation with the workgroup of Dr. Andreas Kremling of the Max-Planck-Institut für Dynamik komplexer technischer Systeme in Magdeburg who performs mathematical modeling. The topic of our workpackage deals with "K+ homeostasis in Escherichia coli", wherby the K+ transporters,
Expertise: Systems Biology, regulation of gene expression, Signal transduction in Gram-negative bacteria; Synthetic Microbiology; Single cell gene expression; Regulatory networks; biochemistry; histidine ki..., gene regulation, stress responses, bistability, sporulation, phenotypic heterogeneity, translational control of gene expression, Bacillus subtilis, Molecular Biology, Genetics, Microbiology
Tools: Time-lapse fluorescence microscopy Flow cytometry, time lapse microscopy, Molecular biology techniques (RNA/DNA), Fluorecence based reporter gene analyses/single cell analyses, PCR, Model organisms, Single Cell analysis, Genetic modification, Genetic analysis, Molecular Biology, Genetics, Microbiology
I am interested in the coupling of global regulation and metabolism in E. coli. To analyze this I construct and analyze defined mutant strains. These strains are characterized in bioreactor experiments of different types (batch, conti, pulse ...) and measurements on the level of metabolites, mRNA, and protein are applied. For all projects there are cooperation partners that use the data in modeling approaches either from the MPI Magdeburg or from the SUMO consortium.