Expertise: medical diagnostics, clinical chemistry, healthcare, biomarkers, Ontology
Tools: biomarkers, Biochemistry, Metabolomics, Proteomics
Projects: INBioPharm
Institutions: Norwegian University of Science and Technology
Projects: WURSynBio, INDIE - Biotechnological production of sustainable indole
Institutions: Wageningen University & Research
Projects: HUMET Startup
Institutions: Leiden University Medical Center

Professor in genetics and systems biology of the metabolic syndrome
Projects: HUMET Startup
Institutions: University Medical Center Hamburg - Eppendorf Hamburg
Expertise: Lipids, metabolism, Metabolic Models, mouse studies
Expert in lipid metabolism and adipose tissue
Expertise: Metabolic Control Analaysis, Metabolomics, Metabolic Networks
Tools: Metabolomics, Transcriptomics
POSITION Professor of Systems Medicine/Biology at the Academic Medical Center, Amsterdam and University Medical Center Groningen, Groningen, The Netherlands
RESEARCH My major projects focus on understanding the etiology of metabolic syndrome and its comorbidities type2 diabetes and cardiovascular disease. To get grip on the sequence of events in disease progression we make use of longitidunal models and apply multiscal systems biology approaches.
PUBLICATIONS
My published work can be found at: ...
Projects: SilicoTryp, SYSTERACT, SynBio4Flav
Institutions: University of Glasgow, Chalmers University of Technology

Projects: SysMO-LAB
Institutions: University of Rostock
Expertise: Molecular microbiology
Tools: Biochemistry and protein analysis, Genetic modification, Metabolomics
Projects: SilicoTryp
Institutions: University of Glasgow
Expertise: Metabolomics
Tools: Metabolomics, Cell culture, GC and LC/MS analysis of metabolites
Projects: SysMO-LAB
Institutions: Wageningen University & Research
Expertise: Bioinformatics, Mathematical modelling, Reactor models, dynamics of biological networks.
Tools: Molecular Biology, Cell biology, Computational and theoretical biology, Metabolomics, Model organisms, SBML, ODE, Partial differential equations, Algebraic equations, Linear equations, Copasi, JWS Online, Matlab, Mathematica, SQL, Material balance based modeling
I'm a modeller, specialized in kinetic modeling of biochemical networks. My focus in the SysMO-LAB consortium is on creating models of Lactococcus lactis glycolysis and couple this to other related lactic acid bacteria like Streptococcus pyogenes and Enterococcus faecalis. Besides kinetic modeling, I'm also interested in combining various modeling techniques (genome-scale modeling, qualitative modeling).
Projects: SysMO-LAB, SysMilk, IMOMESIC
Institutions: Wageningen University & Research, VU University Amsterdam

Expertise: Metabolic Pathway Analysis and Engineering Microbial Physiology Modeling of Biological Networks Industrial Systems Biotechnology White Biotech..., genome-scale modeling, enzyme kinetics, Dynamics and Control of Biological Networks
Tools: Metabolomics, enzymatic analyses, Chemostat culture, Kinetic Modeling
Since August 2008 I am professor in Systems Biology at the VU University Amsterdam. My Systems Bioinformatics group focusses on systems biology with a special focus on integrative bioinformatics. It aims at forming bridges between the classical bottom-up approaches in systems biology and the more data-driven approaches in classical bioinformatics. We combine experimental, modeling and theoretical approaches to study cellular physiology, with an emphasis on metabolic networks.
Projects: COSMIC
Institutions: Wageningen University & Research
PostDoc at Wageningen University, Laboratory of Microbiology
Projects: BaCell-SysMO
Institutions: University of Braunschweig
University Education: 1987-1993, Biotechnology (Diploma), Technische Universität Braunschweig, Germany.
Dissertation: 1993-1996, Disseration German Research Centre for Biotechnology, Biochemical Engineering Division, Braunschweig, Germany.
Habiliation: 2006, Saarland University, Saarbrücken, Germany.
Positions 1993-1996: Research Assistant, German Research Centre for Biotechnology, Biochemical Engineering Division, Braunschweig, Germany. 1997-1998: Post-doc at Department of Applied Chemistry & ...
Projects: COSMIC
Institutions: Wageningen University & Research
Expertise: Microbiology, Molecular Biology
Tools: Biochemistry and protein analysis, Genomics, Transcriptomics, Metabolomics, Fermentation
I am assistant professor at the Laboratory of Microbiology and my interest is in the area of molecular microbiology. Research focuses on the analysis of the metabolism of anaerobic fermentative bacteria and archaea, especially with respect to biofuel production (hydrogen, butanol). Within SysMo our tasks concern the effect of butanol stress, using metabolomics and transcriptomics.
Projects: MOSES, ExtremoPharm, ZucAt, GenoSysFat, DigiSal, EraCoBiotech 2 nd call proposal preparation, FAIRDOM & LiSyM & de.NBI Data Structuring Training
Institutions: University of Stuttgart, University of Hohenheim, Norwegian University of Life Sciences, Norwegian University of Science and Technology

Expertise: Biochemistry, coupling metabolome and environome, rapid sampling experiments, Systems Biology, carbon metabolism, Stoichiometric modelling, Proteomics, Metabolomics, yeast, fungi, Dynamics and Control of Biological Networks
Tools: Biochemistry and protein analysis, Metabolomics, Matlab, Fermentation, Chromatography, Material balance based modeling, stimulus response experiments, continuous cultivation, Enzyme assay, Mass spectrometry (LC-MS/MS), HPLC, GC and LC/MS analysis of metabolites, ODE, Parameter estimation
I've become a SysMO DB PAL for MOSES project in 2007 being a post-doc in lab of Prof. Matthias Reuss at University of Stuttgart. In the MOSES project, our major efforts were in the experimental data acquisition for dynamic model of primary carbon and anaerobic energy metabolism in yeast. The model implements prediction of perturbations of two types: glucose pulse and temperature jump. We implement “stimulus-response” methodology for the unraveling the dynamic structure of the network and to ...
Projects: MOSES
Institutions: VU University Amsterdam