Expertise: Bioinformatics, Computational Systems Biology, Data Management, Databases, Python, R, Transcriptomics, Image analysis, Genomics, Molecular Biology, Microbiology, Data analysis, Genetics
Tools: qPCR, Isolation purification and separation, Genomics, Data Science, RNA / DNA Techniques, Transcriptomics, Microbiology, Molecular Biology, Databases
I am a biochemist & bio-informatician working in phytobacteriology at the Plant Sciences Unit of ILVO, the Flanders Research Institute for Agricultural, Fisheries and Food Research. The focus is on genomics-based research and diagnostics for Plant Health.
My expertise is 'wet-lab' work (microbiology, sequencing, molecular biology, design & validation of diagnostics assays using qPCR/LAMP, automatisation) and 'dry-lab' work such as bio-informatics/data analysis (e.g. scripting analysis ...
Institutions: University of Freiburg
https://orcid.org/0000-0002-5340-3423Expertise: Bioinformatics, Databases, Genetics, Genomics, Systems Biology, Transcriptomics, Microbiology, Microarray analysis
Tools: Bioinformatics, Data analysis, Genetics, Genomics, Microarray analysis, Microbiology, Molecular Biology, Molecular biology techniques (RNA/DNA/Protein), Transcriptomics
Projects: COVID-19 Disease Map
Institutions: University of Surrey
https://orcid.org/0000-0001-5640-7422Reader (Professor) of Systems Biology; Executive Director for the International Society of Systems Biology (ISSB); Editor-in-Chief of Current Opinion in Systems Biology (Elsevier).
Projects: COVID-19 Disease Map
Institutions: Fundación Progreso y Salud
https://orcid.org/0000-0003-2632-9587Expertise: Medicine, Molecular Biology, Virology, Immunology
Tools: Molecular Biology, Molecular biology techniques (RNA/DNA/Protein)
Projects: COVID-19 Disease Map
Institutions: Yenepoya University
Expertise: Biochemistry, Data analysis, Systems Biology, Data Integration
Tools: Proteomics, Systems Biology, Molecular Biology, Bioinformatics, Data Integration
Projects: Finding interaction partners of thylakoid membrane insertase, Characterization of P. tricornutum chloroplast protein mutants
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-0584-6748Expertise: Molecular Biology, photobiology, genome engineering, Biochemistry, Diatoms, Phaeodactylum tricornutum
Tools: CRISPR/Cas9, Molecular Biology, Proteins, photobiology
Projects: HOTSOLUTE
Institutions: Consiglio Nazionale delle Ricerche
https://orcid.org/0000-0002-3399-7973Projects: iRhythmics
Institutions: Leibniz Institute for Farm Animal Biology (FBN)
https://orcid.org/0000-0002-7968-3152Projects: Not specified
Institutions: Not specified
Projects: pISA-tree, HYp - Spatiotemporal analysis of hypersensitive response to Potato virus Y in potato, INDIE - Biotechnological production of sustainable indole, _p_stRT, ADAPT - Accelerated Development of multiple-stress tolerAnt PoTato, tst, tst2
Institutions: National Institute of Biology, tst
https://orcid.org/0000-0002-1669-6482Expertise: Molecular Biology, Statistics, Bioinformatics, Mathematical and statistical modeling, Programming, Data analysisMathematical modellingBioinformaticsSystems biology, Data Management, Data analysis, Visualization, Data Integration, Computational Biology
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Molecular Biology, Python, R, Systems Biology, Data Integration
Computational Biologist and Biostatistician at Department of Biotechnology and Systems Biology, National Institute of Biology (NIB)
Projects: Sustainable co-production
Institutions: University of Rostock
Projects: HYp - Spatiotemporal analysis of hypersensitive response to Potato virus Y in potato, pISA-tree, MOA - Multiomics analysis of potato response to Potato virus Y (PVY) infection, SUSPHIRE - Sustainable Bioproduction of Pheromones for Insect Pest Control in Agriculture, INDIE - Biotechnological production of sustainable indole, FAIRDOM user meeting, _p_stRT, ADAPT - Accelerated Development of multiple-stress tolerAnt PoTato
Institutions: National Institute of Biology
https://orcid.org/0000-0001-5906-8569Projects: OXYMOD
Institutions: Norwegian University of Science and Technology
Projects: OXYMOD
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0002-1644-3223Expertise: protein NMR, lytic polysaccharide monooxygenases
Tools: NMR, Molecular Biology, Biochemistry and protein analysis, Python
Projects: OXYMOD
Institutions: Norwegian University of Science and Technology
https://orcid.org/0000-0003-1613-4663Projects: EmPowerPutida
Institutions: Wageningen University & Research
Projects: PHYTOCAL: Phytochrome Control of Resource Allocation and Growth in Arabidopsis and in Brassicaceae crops, Light and plant development, Light control of leaf development
Institutions: University of Edinburgh
https://orcid.org/0000-0003-0737-2408Expertise: arabidopsis thaliana, caenorhabditis elegans, circadian rhythms, chronobiology, Transcriptomics, splicing, alternative splicing, R, photobiology, plant architecture, leaf development
Tools: Molecular Biology, Molecular biology techniques (RNA/DNA/Protein), R, Systems Biology, Transcriptomics, Bioinformatics, Databases, Genetics, Plant biology, C. elegans biology
Projects: BioZEment 2.0, BESTER, Auromega, C1Pro, AquaHealth (ERA-BlueBio)
Institutions: SINTEF
Projects: WURSynBio
Institutions: Wageningen University & Research
Projects: EmPowerPutida
Institutions: LifeGlimmer GmbH
Expertise: Bioinformatics, Systems Biology, Transcriptomics, R, Genomics, Proteomics, Databases, Data Integration
Tools: Bioinformatics, Molecular Biology, Computational Systems Biology
Computational Biologist and App Designer @LifeGlimmer
Projects: SYSTERACT
Institutions: University of Tübingen
Projects: HUMET Startup
Institutions: Wageningen University & Research
https://orcid.org/0000-0003-4488-7734Expertise: Lipids, Nutrition, metabolism, nuclear receptors
Tools: Microarray analysis, Molecular Biology, Cell and tissue culture
Dr. Sander Kersten received his PhD in Nutritional Biochemistry from Cornell University in 1997. After a postdoctoral stay in the laboratory of Dr. Walter Wahli at the University of Lausanne, Switzerland, he moved to Wageningen in 2000, initially as a fellow of the Royal Netherlands Academy of Arts and Sciences and later as Associate Professor. Since 2011 he is Full Professor in Molecular Nutrition and since 2014 chair of the Nutrition, Metabolism and Genomics group. His current research interests ...
Projects: GenoSysFat, DigiSal
Institutions: Norwegian University of Life Sciences
https://orcid.org/0000-0002-5322-0192Projects: DigiSal, GenoSysFat
Institutions: Norwegian University of Life Sciences
https://orcid.org/0000-0001-7828-2309Expertise: Bioinformatics
Tools: Bioinformatics, Genetics, Transcriptomics, Molecular Biology
Projects: SysMetEx
Institutions: Universitity Duisburg-Essen
My research is intended to contribute to the elucidation of the physiological and molecular processes involved in the biofilm formation of acidophilic leaching bacteria with emphasis in their cell-cell communication mechanisms. In SysMetEx, our role is to understand biofilm formation at a microscopical and OMICS levels, in order to optimize it.
Projects: MetApp
Institutions: ETH Zurich
Expertise: carbon metabolism, Genetics, Biochemistry, Microbiology
Tools: Biochemistry, Genetics, Molecular Biology
Projects: ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Universität Konstanz
Expertise: Molecular Biology, Systems Biology, Mathematical modelling
Tools: quantitative western blot analysis, Molecular Biology, Java, octave, R, ODE
I studied Life Science (which is similar to chemical biology) at the University of Konstanz and became interested in Bioinformatics, Systems Biology and quantitative analyses during my Master's. In my PhD project I combine experimental analyses with modeling and parameter estimation approaches to quantitatively analyse regulation of apoptosis at the level of the Bcl-2 protein family.
I am a PostDoc in prof. Brautaset's lab at NTNU in Trondheim, Norway. During my Ph studies D, Irla was involved in two ERA projects; SynMet and MetAPP (PAL) and currently in I am active in C1Pro project (Asset housekeeper). I have been working with methylotrophic Bacillus methanolicus since 2012, in that time I have been involved in engineering of that bacterium for production of different value-added products (amino acids and their derivatives, vitamins, and others). Furthermore, I have improved ...
Projects: SysMO-LAB
Institutions: University of Rostock
Expertise: Microbiology, Genetics, Molecular Biology, Transcriptomics, Streptococcus pyogenes, Lactococcus, Molecular microbiology, Genetic regulation
Tools: Microbiology, Genetics, Molecular Biology, Genetic modification, Transcriptomics, Microarray analysis, Molecular biology techniques (RNA/DNA/Protein)
Projects: BaCell-SysMO
Institutions: University of Newcastle
Expertise: Microbiology, Molecular Biology, Gram positive bacteria (Bacillus, Systems Biology, Genetics)
Tools: Microbiology, Molecular Biology, Biochemistry and protein analysis, Cell biology, Genetic analysis, Genomics, Transcriptomics, Proteomics, Model organisms, Proteomics (2D-PAGE), gene regulation, DNA technology RNA technology Protein analysis Fermentation Mutagenesis, molecular biological techniques (RNA/DNA techniques), protein interaction studies
Optimisation of Bacillus subtilis for the secretion of heterologous proteins Therapeutic proteins (including those required for experimental purposes and clinical trials) are major products of biomanufacturing processes and considerable time and expense are expended to maximise the yield and quality of proteins produced in heterologous hosts. The production host of choice is the Gram-negative bacterium Escherichia coli for which many strains and expression systems have been developed. However, ...
Projects: BaCell-SysMO
Institutions: University Medical Centre Groningen
The main area of my expertise concerns protein sorting and secretion in Gram-positive bacteria, such as Bacillus subtilis and Staphylococcus aureus.
The Gram-positive bacterium B. subtilis is well known for its high capacity to secrete proteins into the extracellular milieu, which has led to its exploitation as a "cell factory" for secreted proteins. Nevertheless, the secretion of heterologous proteins of pharmaceutical importance is frequently inefficient. This applied problem has been a major ...
Projects: COSMIC
Institutions: University of Goettingen
I`m interested to investigate the Influence of the accumulation of reduction equivalents on solvent production
Projects: SulfoSys, SulfoSys - Biotec, HOTSOLUTE, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers
Institutions: University Duisburg-Essen, Universitity Duisburg-Essen
https://orcid.org/0000-0002-9905-541XHead of the group of Molecular Enzyme Technology and Biochemistry (Faculty of Chemistry) at the University of Duisburg-Essen. My research interest is on archaeal physiology with a special focuss on the central carbohydrate metabolism of (hyper)thermophilic Archaea and its regulation. The aim is to gain a systems level understanding by the combination of modern highthrouput analyses with classical biochemistry and molecular biology. Archaea possess many novel enzymes and pathways and our aim is ...
Projects: SulfoSys
Institutions: University Duisburg-Essen
Tools: Biochemistry, Molecular Biology, Enzyme assays
Projects: SulfoSys, SulfoSys - Biotec, Glucose metabolism in cancer cell lines
Institutions: University Duisburg-Essen, Stellenbosch University
Projects: PSYSMO
Institutions: University of Braunschweig
Expertise: Microbiology, Molecular Biology, Transcriptomics, Anaerobic Microbiology, Bacterial metabolism | Metabolic engineering, Regulatory Networks
Tools: Genetics, Molecular Biology, Genetic modification, Microarray analysis, Proteomics (2D-PAGE), time lapse microscopy, Molecular biology techniques (RNA/DNA/Protein), qRT-PCR
Projects: BaCell-SysMO
Institutions: University of Greifswald
Institutions: University of Amsterdam
Expertise: Microbiology, Biochemistry, Molecular Biology, Escherichia coli, HPLC
Tools: Biochemistry, Molecular Biology, Fermentation, Chromatography
Martijn Bekker (1979) was born in Amstelveen (The Netherlands). He started his studies in biology in 1997 at the University of Amsterdam, and graduated in 2003 with specializations in molecular microbiology and in immunology. The internships during his undergraduate studies were carried out in the labs of Prof. dr. B. Oudega (VU, Amsterdam, The Netherlands) and Prof. dr. F. Heffron (OHSU, Portland, Oregon, USA). He continued with his graduate studies in 2003 in the Laboratory for Molecular Microbial ...
Projects: COSMIC
Institutions: Wageningen University & Research
Expertise: Microbiology, Genetics, Molecular Biology, Systems Biology, Anaerobic Microbiology, Clostridial Genetics, Metabolic Engineering, Synthetic Biology, bacterial metabolism, carbon metabolism, Clostridium
Tools: Microbiology, Molecular Biology, Chromatography, Molecular biology techniques (RNA/DNA/Protein)
I'm an experimentalist 'Pre-doc' (I still have to finish my PhD thesis) and my work on the COSMIC project will focus on setting up a metabolomic analysis method for Clostridium acetobutylicum. In the past I have worked on metabolic engineering of the same organism by disrupting genes to asses their impact on acid and solvent formation. I'm looking forward to joining the COSMIC web-community. It hopefully will all us to stay in touch and update each other on advances in the (computer)lab.
Projects: KOSMOBAC
Institutions: University of Aberdeen
My research interests are in the physiology of bacteria subjected to stress. The focus of my recent research has been the structure and function of regulated transport systems and ion channels involved in cellular homeostasis. These transporters and channels respond to specific signals by a change in activity that either corrects the imposed stress or protects the cell during exposure to the stress. Our systems biology interests are in the interplay of different enzymes systems and transporters ...
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Gram positive bacteria (Bacillus, Lactococcus, Streptococcus), competence, sporulation, germination, antimicrobial peptides, phenotypic heterogeneity, bistability, C- and N- metabolism, gene regulation, stress responses, pathogens, virulence factors, metal ion homeostasis, protein secretion
Tools: Biochemistry, Genetics, Molecular Biology, Bioinformatics, Genomics, Transcriptomics, time lapse microscopy, FACS, genomic array footprinting
Group leader Molecular Genetics
Projects: KOSMOBAC
Institutions: Max-Planck-Institute of Biochemistry Martinsried
Expertise: Microbiology, Biochemistry, Molecular Biology, Bioinformatics, Mathematical modelling, sequencing
Tools: Microbiology, Molecular Biology, Bioinformatics, Biochemistry and protein analysis, Matlab, Fermentation, rtPCR, molecular biological techniques (RNA/DNA techniques, qPCR, Transcriptomics
Professor in Jinan University, Guangzhou, China. My research interest is in the modeling of translation. Connecting various processes in translation, we can investigate the impact of different factors on protein biosynthesis and biogenesis in genome-wide scale. This may reveal various general mechanisms on control level of gene expression and folding efficiency regulation in different growth conditions.
Projects: KOSMOBAC
Institutions: University of Aberdeen
Expertise: Microbiology, Molecular Biology, Escherichia coli Membrane protein Biochemistry
Tools: Microbiology, Molecular Biology, Biochemistry of substrate transport. molecular biological techniques (RNA/DNA techniques analyses of transport across cell membranes heterologous e..., Membrane protein biochemistry, Chemical cross-linking, Site-directed mutagenesis
I am a biologist by training. My research career is focussed on the structure-function relationships of membrane transport systems in Escherichia coli. I am interested in understanding the mechanism of ion and solute transport across the membrane and how this influences bacterial cell survival. My work mainly focusses on the ligand-gated potassium efflux systems which are crucial for cell survival during electrophile exposure and the mechanosensitive channels involved in hypoosmotic stress ...
Projects: KOSMOBAC
Institutions: University of Aberdeen
Expertise: Chip-chip, Recombineering
Tools: Genetics, Molecular Biology, Genomics, Chip-chip, Enzyme assay
I am final year PhD student in Prof Ian Booth's lab and a microbiologist by trade. I am interested in how enteric bacteria cope with stress and what systems they employ to increase their chances of survival, in particular upon methylglyoxal stress.
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Microbiology, Genetics, Molecular Biology, Bacillus subtilis, translational control of gene expression, sporulation, phenotypic heterogeneity, bistability, gene regulation, stress responses, Signal transduction in Gram-negative bacteria; Synthetic Microbiology; Single cell gene expression; Regulatory networks; biochemistry; histidine ki..., regulation of gene expression, Systems Biology
Tools: Microbiology, Genetics, Molecular Biology, Genetic analysis, Genetic modification, Model organisms, Single Cell analysis, PCR, Fluorecence based reporter gene analyses/single cell analyses, Molecular biology techniques (RNA/DNA), time lapse microscopy, Time-lapse fluorescence microscopy Flow cytometry
Projects: COSMIC
Institutions: University of Nottingham
A molecular microbiologist with a passion for Clostridia! Interested in the development of more effective countermeasures (diagnosis, prevention & treatment) against pathogens, specifically Clostridium difficile and Clostridium botulinum as well as the exploitation of the medical and industrial properties of beneficial strains, specifically in cancer therapy and biofuel production
Projects: BaCell-SysMO
Institutions: University of Goettingen
Expertise: Microbiology, Genetics, Molecular Biology, Bacillus subtilis, regulation of gene expression, protein-protein interactions, Mycoplasma pneumoniae, Cell physiology, protein-RNA interactions
Tools: Microbiology, Molecular Biology, Biochemistry and protein analysis, Genetic analysis, Genetic modification, Proteomics (2D-PAGE), mutant strain generation, Chemical cross-linking, SubtiWiki, SPINE, bacterial two-hybrid system
Projects: BaCell-SysMO
Institutions: University of Greifswald
Expertise: Microbiology, Molecular Biology, Bacillus subtilis, stress responses, functional protein expression, carbon metabolism
Tools: Molecular Biology, Biochemistry and protein analysis, Proteomics, Proteomics (2D-PAGE), 2-D Gel Electrphoresis, GeLC-MS/MS, metabolic labeling, absolute quantification, AQUA
I'm Post-Doc in the lab of Prof. Becher at the University of Greifswald. I'm working on the relative and absolute protein quantitation using gel-based and mass-spectrometric methods.
Projects: SysMO-LAB
Institutions: Wageningen University & Research
Expertise: Bioinformatics, Mathematical modelling, Reactor models, dynamics of biological networks.
Tools: Molecular Biology, Cell biology, Computational and theoretical biology, Metabolomics, Model organisms, SBML, ODE, Partial differential equations, Algebraic equations, Linear equations, Copasi, JWS Online, Matlab, Mathematica, SQL, Material balance based modeling
I'm a modeller, specialized in kinetic modeling of biochemical networks. My focus in the SysMO-LAB consortium is on creating models of Lactococcus lactis glycolysis and couple this to other related lactic acid bacteria like Streptococcus pyogenes and Enterococcus faecalis. Besides kinetic modeling, I'm also interested in combining various modeling techniques (genome-scale modeling, qualitative modeling).