Expertise: mRNA, overflow metabolism in Bacillus, carbon catabolite regulation in Gram positive bacteria, Clostridium, carbon metabolism, regulation of gene expression, Bacillus subtilis, Molecular Biology, Microbiology
Tools: microbiology techniques, Western blot analyses, reporter gene analyses, qRT-PCR, absolute quantification, Optimal experimental design, Molecular biology techniques (RNA/DNA), cultivation, northern blot analysis, Genetic modification
Expertise: fungi, yeast, Metabolomics, Proteomics, Stoichiometric modelling, carbon metabolism, Systems Biology, dynamics and control of biological networks, coupling metabolome and environome, rapid sampling experiments, Biochemistry
Tools: parameter estimation, ODE, HPLC, GC and LC/MS analysis of metabolites, Mass spectrometry (LC-MS/MS), continuous cultivation, Enzyme assay, Material balance based modeling, stimulus response experiments, Chromatography, Fermentation, Matlab, Metabolomics, Biochemistry and protein analysis
I've become a SysMO DB PAL for MOSES project in 2007 being a post-doc in lab of Prof. Matthias Reuss at University of Stuttgart. In the MOSES project, our major efforts were in the experimental data acquisition for dynamic model of primary carbon and anaerobic energy metabolism in yeast. The model implements prediction of perturbations of two types: glucose pulse and temperature jump. We implement “stimulus-response” methodology for the unraveling the dynamic structure of the network and to
I'm Post-Doc in the lab of Prof. Becher at the University of Greifswald. I'm working on the relative and absolute protein quantitation using gel-based and mass-spectrometric methods.
Expertise: Cell physiology, regulation of gene expression, quantative biology, Protein-DNA-interaction, Microbiology/ Protein chemistry/ Molecular Biology, Bacterial Cell Biology, carbon metabolism, bacterial metabolism, functional protein expression, Bacillus subtilis
Tools: surface plasmon resonance spectroscopy, reporter gene analysis, DNA, Molecular biology techniques (RNA/DNA/Protein), Chromatography, Model organisms, Cell biology, Biochemistry and protein analysis, Microbiology
Expertise: Clostridium, carbon metabolism, bacterial metabolism, Anaerobic Microbiology, Synthetic Biology, Clostridial Genetics, Metabolic Engineering, Systems Biology, Molecular Biology, Genetics, Microbiology
I'm an experimentalist 'Pre-doc' (I still have to finish my PhD thesis) and my work on the COSMIC project will focus on setting up a metabolomic analysis method for Clostridium acetobutylicum.
In the past I have worked on metabolic engineering of the same organism by disrupting genes to asses their impact on acid and solvent formation.
I'm looking forward to joining the COSMIC web-community. It hopefully will all us to stay in touch and update each other on advances in the (computer)lab.
Expertise: metabolic networks, carbon metabolism, Signalling networks, Nonlinear Dynamics, Systems Biology, stress responses, Mathematical modelling of biosystems and bioprocesses, Bacillus subtilis, Mathematical modelling, Biochemistry, Microbiology
Tools: fed-batch cultivation, Dynamic modelling, Computational Systems Biology, Deterministic models, Enzyme assay, continuous cultivation, Chromatography, Fermentation, Matlab, Mathematica, ODE, Computational and theoretical biology
I am a biologist in the lab of Prof. Reuss at the University of Stuttgart and I am working in the field of biotechnology and mathematical modelling.