Projects: Simulation Foundries, CML for thermophysical properties of mixtures, Test Project (dummy), Towards Reproducible Enzyme Modeling
Institutions: University of Stuttgart, Karlsruhe Institute of Technology (KIT)
https://orcid.org/0000-0001-9119-1778Expertise: enzyme kinetics, enzymes, Enzymatic reactions, biochemical enzyme characterization, Biochemistry, molecular simulation, molecular modeling, Programming, Bioinformatics, Computational Biology
Tools: Gromacs, Python, Molecular Dynamics, bash, Biochemistry, Bioinformatics, Biochemistry and protein analysis, Enzyme assay, enzyme kinetics, isothermal titration calorimetry, dynamic light scattering, Spectrophotometry
Polyglot European Scientist. I thrive working in interdisciplinary environments combining the study of enzyme reactions and mechanisms with bioinformatics, molecular modelling, automated data analysis and data stewardship.
Projects: SysMO-LAB, MOSES, PSYSMO, SulfoSys, SulfoSys - Biotec, EraCoBiotech 2 nd call proposal preparation, Make Me My Model, Mechanism based modeling viral disease ( COVID-19 ) dynamics in human population, Modelling COVID-19 epidemics, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation, Xenophiles Systems Biology, Thermodynamics, Non equilibrium thermodynamics, Book on Thermodynamics, and kinetics, Teaching Alien Biology, Outdated material, Fusion-fission-mitophagy, Stochastics and bursting
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, VU University Amsterdam, University of Amsterdam, Systems Biology Amsterdam
https://orcid.org/0000-0002-0443-6114Systems Biologist at University of Amsterdam, Free University Amsterdam, University of Manchester, Infrastructure Systems Biology.NL (ISBE.NL), Systems Biology Amsterdam.
Projects: COVID-19 Disease Map
Institutions: University of Surrey
https://orcid.org/0000-0001-5640-7422Reader (Professor) of Systems Biology; Executive Director for the International Society of Systems Biology (ISSB); Editor-in-Chief of Current Opinion in Systems Biology (Elsevier).
Expertise: medical diagnostics, clinical chemistry, healthcare, biomarkers, Ontology
Tools: biomarkers, Biochemistry, Metabolomics, Proteomics
Projects: HOTSOLUTE
Institutions: Consiglio Nazionale delle Ricerche
https://orcid.org/0000-0002-3399-7973Expertise: Protein and Enzyme structure and mechanism, Thermophilic proteins in industrial biocatalysis, Biochemistry, Bioinformatics, Microbiology, Molecular Biology, Proteomics
Tools: Biochemistry, Biochemistry and protein analysis, Bioinformatics, Microbiology, Molecular biology techniques (RNA/DNA/Protein), Proteomics
Projects: BioZEment 2.0, BESTER, Auromega, C1Pro, AquaHealth (ERA-BlueBio)
Institutions: SINTEF
Expertise: Fermentation, Analytical chemistry
Tools: Fermentation, HPLC, Biochemistry, Matlab
Projects: SBEpo - Systems Biology of Erythropoietin
Institutions: German Cancer Research Center (DKFZ)
https://orcid.org/0000-0002-0971-2309Expertise: Mathematical modelling, Single Cell analysis, Cell biology, Molecular Biology
Tools: Biochemistry, Systems Biology, Matlab, R
Projects: The Hedgehog Signalling Pathway (LiSyM-JGMMS)
Institutions: Universität Leipzig - Medizinische Fakultät - Institut für Biochemie
Expertise: Biochemistry, Cell biology, Molecular Biology
Tools: Biochemistry
Projects: SYSTERACT
Institutions: University of Tübingen
Expertise: chromatin, Epigenetics, nuclear organisation, DNA repair
Tools: quantitative microscopy, Biochemistry, Systems Biology, Cell biology
POSITION I am an emeritus professor in Biochemistry at the University of Amsterdam (retired 2010).
RESEARCH My research focussed on the human chromatin in its natural environment, i.e. the nucleus of cultured living human cells. Aspects, such as the dynamic folding of the chromatin fiber inside the nucleus and local chemical modification of histones and DNA at genetic loci, are the physical and chemical basis for epigenetic regulation of gene expression. In my group we worked parallel on human ...
Projects: MetApp
Institutions: ETH Zurich
Expertise: carbon metabolism, Genetics, Biochemistry, Microbiology
Tools: Biochemistry, Genetics, Molecular Biology
Projects: SulfoSys, SulfoSys - Biotec, HOTSOLUTE, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers
Institutions: University Duisburg-Essen, Universitity Duisburg-Essen
https://orcid.org/0000-0002-9905-541XHead of the group of Molecular Enzyme Technology and Biochemistry (Faculty of Chemistry) at the University of Duisburg-Essen. My research interest is on archaeal physiology with a special focuss on the central carbohydrate metabolism of (hyper)thermophilic Archaea and its regulation. The aim is to gain a systems level understanding by the combination of modern highthrouput analyses with classical biochemistry and molecular biology. Archaea possess many novel enzymes and pathways and our aim is ...
Projects: SulfoSys
Institutions: University Duisburg-Essen
Tools: Biochemistry, Molecular Biology, Enzyme assays
Projects: BaCell-SysMO
Institutions: University of Rostock
Expertise: Mathematical modelling, Bacillus subtilis, Deterministic modelling of gene regulation networks, stress responses, Systems Biology, sensitivity analysis, Dynamics and Control of Biological Networks, Parameter estimation
Tools: Biochemistry, Computational and theoretical biology, ODE, Matlab, linux, Stochastic models, Deterministic models, Dynamic modelling
Modelling of the general stress response activation cascade of sigB in B. subtilis in response to starvation.
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Gram positive bacteria (Bacillus, Lactococcus, Streptococcus), competence, sporulation, germination, antimicrobial peptides, phenotypic heterogeneity, bistability, C- and N- metabolism, gene regulation, stress responses, pathogens, virulence factors, metal ion homeostasis, protein secretion
Tools: Biochemistry, Genetics, Molecular Biology, Bioinformatics, Genomics, Transcriptomics, time lapse microscopy, FACS, genomic array footprinting
Group leader Molecular Genetics
Projects: Noisy-Strep
Institutions: University of Groningen
Expertise: Microbiology, Genetics, Molecular Biology, Single Cell analysis, Bacillus subtilis, Bacterial Cell Biology, Molecular microbiology, Medical microbiology, Streptococcus pneumoniae
Tools: Microbiology, Biochemistry, Genetics, Genetic modification, Transcriptomics, Fluorecence based reporter gene analyses/single cell analyses, Molecular biology techniques (RNA/DNA/Protein)
The Veening lab is interested in phenotypic bi-stability in Streptococcus pneumoniae and its importance in virulence of this human pathogen.
Institutions: University of Amsterdam
Expertise: Microbiology, Biochemistry, Molecular Biology, Escherichia coli, HPLC
Tools: Biochemistry, Molecular Biology, Fermentation, Chromatography
Martijn Bekker (1979) was born in Amstelveen (The Netherlands). He started his studies in biology in 1997 at the University of Amsterdam, and graduated in 2003 with specializations in molecular microbiology and in immunology. The internships during his undergraduate studies were carried out in the labs of Prof. dr. B. Oudega (VU, Amsterdam, The Netherlands) and Prof. dr. F. Heffron (OHSU, Portland, Oregon, USA). He continued with his graduate studies in 2003 in the Laboratory for Molecular Microbial ...
Projects: SUMO
Institutions: Max Planck Institute for Dynamics of Complex Technical Systems
Projects: SulfoSys, SulfoSys - Biotec, Glucose metabolism in cancer cell lines
Institutions: University Duisburg-Essen, Stellenbosch University