Systems toxicology of Atlantic cod
OverviewCoastal zones and oceans constitute an essential fundament for Norway’s history as well as current economy, providing ecosystem services for fisheries, aquaculture, transport, tourism, and recreation. The petroleum activities in Norwegian waters have been crucial for Norway’s financial growth and in financing the Norwegian welfare state. As the pressure on the oceans continuously increases, both the petroleum industry and the seafood industries have acknowledged that awareness and actions are required to maintain a healthy marine environment to secure Norway´s future marine bioeconomy. Marine industries must also comply with governmental and international regulations regarding sustainable practices of marine activities, and novel technologies are needed in order to efficiently cope with such future demands.
The goal of the dCod-project is to combine the competencies in environmental toxicology, biology, bioinformatics and mathematics across the traditional department boundaries, to create a deeper understanding of cods' adaptations and reactions to stressors in the environment. The projects aims to generate large amounts of experimental data to be the basis of mathematical models that can describe these responses based on different scenarios. Furthermore, the overall goal is to create a tool for environmental monitoring and risk assessment that can be used in assessing the impacts of for example the oil industry, sewage discharge into harbours and industrial discharge into Norwegian fjords.
The project is associated with the Centre for Digital Life Norway.
Programme: dCod 1.0: decoding systems toxicology of cod
SEEK ID: https://fairdomhub.org/projects/60
Public web page: http://www.uib.no/en/dcod
Organisms: Gadus morhua
FAIRDOM PALs: No PALs for this Project
Project created: 5th Feb 2017
Related items
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
https://orcid.org/0000-0002-8839-3333
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
https://orcid.org/0000-0003-4054-9842
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
https://orcid.org/0000-0003-0073-3282
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
This study involves all data gathered from the Kollevåg study - studying environmental pollution at a capped waste disposal site in Kollevåg, Askøy.
Cod were caged in Kollevåg (Stations 1, 2 and 3 - from inner to outer parts) and at a reference location (Ref station) for a period of six weeks, from 2nd September 2016, to 17-18th October 2016.
Information about the fish from the Kollevåg study
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Enzyme activity of glutathione-s-transferase (Gst) and catalase (Cat) in Kollevåg samples
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Enzymatic Activity Measurements
Snapshots: No snapshots
Concentrations of steroid hormones E2 and T in female cod plasma from Kollevåg fish
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Chemical analyses in Kollevåg includes sediment contaminant concentrations, concentrations of various contaminants in cod liver and concentrations of PAH metabolites in cod bile.
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Western blot results for Kollevåg samples.
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Analyses of gene expression: qPCR analyses in liver (relative expression) and ovaries (absolute expression).
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
TBARS assay measured oxidative stress as levels of malondialdehyde in samples.
Performed in cod liver samples.
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Biosense Vtg assay measuring concentrations of vitellogenin in cod blood plasma
Contributor: Karina Dale
Assay type: Experimental Assay Type
Technology type: Technology Type
Snapshots: No snapshots
Concentrations of vitellogenin in blood plasma in cod caged in Kollevåg and at reference location.
Creators: None
Contributor: Karina Dale
DownloadMeasurement of oxidative stress (TBARS) assay in liver of cod caged in Kollevåg and at reference location.
Creators: None
Contributor: Karina Dale
Gene expression data of genes involved in steroidogenic pathways, measured in cod ovaries.
Creators: None
Contributor: Karina Dale
Relative protein expression of the proteins Cyp3a and Mt in cod from the Kollevåg study
Creators: None
Contributor: Karina Dale
Measurements of PAH metabolites in bile in fish caged in Kollevåg.
Creator: Karina Dale
Contributor: Karina Dale
Concentrations of various contaminants in liver from cod caged in Kollevåg and at reference location.
Creators: None
Contributor: Karina Dale
Concentrations of E2 and T in cod plasma of female cod caged in Kollevåg measured by enzyme immunoassay.
Creators: None
Contributor: Karina Dale
Concentrations of metals, PAHs and PCBs in sediment samples from Kollevåg and reference site.
Creators: None
Contributor: Karina Dale
Measurement of Gst and Cat enzyme activity in liver of fish caged in Kollevåg.
Creator: Karina Dale
Contributor: Karina Dale
Abstract (Expand)
Author: Fekadu Yadetie, Eystein Oveland, Anne Døskeland, Frode Berven Anders Goksøyr, Odd André Karlsen
Date Published: 1st Apr 2017
Journal: Aquatic Toxicology
Abstract (Expand)
Authors: Fekadu Yadetie, S. Bjorneklett, H. K. Garberg, E. Oveland, F. Berven, A. Goksoyr, O. A. Karlsen
Date Published: 9th Aug 2016
Journal: BMC Genomics
Abstract (Expand)
Authors: Fekadu Yadetie, O. A. Karlsen, A. Lanzen, K. Berg, P. Olsvik, C. Hogstrand, A. Goksoyr
Date Published: 30th Oct 2012
Journal: Aquat Toxicol
Abstract (Expand)
Authors: F. Yadetie, O. A. Karlsen, M. Eide, C. Hogstrand, A. Goksoyr
Date Published: 19th Jun 2014
Journal: BMC Genomics
