In vivo Nord 1: Chlorpyrifos-methyl
DownloadAim: To investigate whether Atlantic cod that feed close to aquatic breeding facilities are affected by chlorpyrifos-methyl. Feeding experiment with chlorpyrifos-methyl, an organophosphorous pesticide detected in plant based salmon feed. Based on previous experiments using salmon.
Doses: 0, 0.5, 5.0, 25 mg/kg) chlorpyrifos-methyl. Duration: 30 days Set-up: Three tanks per treatment (12 in total)
Samples include: Liver, plasma, bile, brain. Analysis include:
- Have RNAseq and metabolomics from 36 liver samples
- Plasma cholinesterase, cortisol, ASAT, ALAT, and total protein (how many?)
- EROD on liver samples (how many?)
- Chemical levels of chlorpyrifos-methyl and main metabolite TCP in liver and bile (how many?)
- Hypoxia stress test (how many?)
DOI: 10.15490/fairdomhub.1.study.593.1
Zenodo URL: None
Created at: 29th May 2019 at 11:28
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Views: 969 Downloads: 9
Created: 29th May 2019 at 11:28
Last updated: 29th May 2019 at 11:28
