Cyp1a activity (=EROD) measured in liver samples of cod exposed to chlorpyrifos-methyl
SEEK ID: https://fairdomhub.org/assays/1050
Experimental assay
Projects: Systems toxicology of Atlantic cod
Investigation: hidden item
Study: In vivo Nord 1: Chlorpyrifos-methyl
Assay position:
Assay type: Experimental Assay Type
Technology type: Technology Type
Organisms: Gadus morhua
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Created: 7th Jun 2019 at 14:15
Last updated: 30th May 2021 at 21:29
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Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
Expertise: Molecular Biology
Projects: Systems toxicology of Atlantic cod
Institutions: University of Bergen
https://orcid.org/0000-0002-5641-9420Expertise: Ecotoxicology
Professor at Nord University, Bodø, Norway
The goal of the dCod-project is to combine the competencies in environmental toxicology, biology, bioinformatics and mathematics across the traditional department boundaries, to create a deeper understanding of cods' adaptations and reactions to stressors in the environment. Building on the thoroughly studies and mapping of the cod genome at UiO and the long research traditions on cod at the Department of Biology at UiB, the dCod project will expand our knowledge with methods based on genomics; ...
Projects: Systems toxicology of Atlantic cod
Web page: http://dcod.no
Coastal zones and oceans constitute an essential fundament for Norway’s history as well as current economy, providing ecosystem services for fisheries, aquaculture, transport, tourism, and recreation. The petroleum activities in Norwegian waters have been crucial for Norway’s financial growth and in financing the Norwegian welfare state. As the pressure on the oceans continuously increases, both the petroleum industry and the seafood industries have acknowledged that awareness and actions are ...
Programme: dCod 1.0: decoding systems toxicology of cod
Public web page: http://www.uib.no/en/dcod
Organisms: Gadus morhua
Aim: To investigate whether Atlantic cod that feed close to aquatic breeding facilities are affected by chlorpyrifos-methyl. Feeding experiment with chlorpyrifos-methyl, an organophosphorous pesticide detected in plant based salmon feed. Based on previous experiments using salmon.
Doses: 0, 0.5, 5.0, 25 mg/kg) chlorpyrifos-methyl. Duration: 30 days Set-up: Three tanks per treatment (12 in total)
Samples include: Liver, plasma, bile, brain. Analysis include:
- Have RNAseq and metabolomics from 36 ...
Submitter: Marta Eide
Investigation: 1 hidden item
Assays: Chemical analyses, EROD activity, Fish biometrics in vivo Nord, Metabolomics, Plasma parameters, Transcriptomics
Snapshots: Snapshot 1, Snapshot 2
EROD activity in liver of cod exposed to chlorpyrifos-methyl
Biometrics of IVN fish exposed to chlorpyrifos-methyl
Investigations: 1 hidden item
Studies: In vivo Nord 1: Chlorpyrifos-methyl
Assays: Chemical analyses, EROD activity, Fish biometrics in vivo Nord, Metabolomics, Plasma parameters, Transcriptomics