Expertise: Signalling networks, dynamics of biological networks., Databases, Data analysis, Systems Biology, Model selection, Identifiability, Cellular Senescence, Cell Cycle, Dynamic Systems, Image processing, Image analysis, Parameter estimation
My group investigates dynamic regulation and control mechanisms of cellular signal transduction networks by a combination of theoretical, experimental and computational methods. We seek to make sense of our biological data with the help of mathematical models, which ideally enable us to make valid predictions for new experiments, thereby generating novel biological insights.
Expertise: Gram positive bacteria (Bacillus, Lactococcus, Streptococcus), competence, sporulation, germination, antimicrobial peptides, phenotypic heterogeneity, bistability, C- and N- metabolism, gene regulation, stress responses, pathogens, virulence factors, metal ion homeostasis, protein secretion
Group leader Molecular Genetics