Jörg Schaber
My group investigates dynamic regulation and control mechanisms of cellular signal transduction networks by a combination of theoretical, experimental and computational methods. We seek to make sense of our biological data with the help of mathematical models, which ideally enable us to make valid predictions for new experiments, thereby generating novel biological insights.
SEEK ID: https://fairdomhub.org/people/445
Disciplines: Modeller, Experimentalist, Bioinformatician
Expertise: Image processing, Image analysis, Dynamic Systems, Signalling networks, dynamics of biological networks., parameter estimation, Databases, Data analysis, Systems Biology, Model selection, Identifiability, Cellular Senescence, Cell Cycle
Tools: Identifiability analysis, Fluorescence and confocal microscopy, parameter estimation, ODE, FACS, Model selection
orcid.org/0000-0001-6971-2530
Jörg's tagsRelated items
Within the e:Bio - Innovationswettbewerb Systembiologie (Federal Ministry of Education and Research (BMBF)), the SulfoSYSBIOTECH consortium (10 partners), aim to unravel the complexity and regulation of the carbon metabolic network of the thermoacidophilic archaeon Sulfolobus solfataricus (optimal growth at 80°C and pH 3) in order to provide new catalysts ‘extremozymes’ for utilization in White Biotechnology.
Based on the available S. solfataricus genome scale metabolic model (Ulas et al., 2012)
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Programme: e:Bio
Public web page: http://www.sulfosys.com/
Systems Biology studies the properties and phenotypes that emerge from the interaction of biomolecules where such properties are not obvious from those of the individual molecules. By connecting fields such as genomics, proteomics, bioinformatics, mathematics, cell biology, genetics, mathematics, engineering and computer sciences, Systems Biology enables discovery of yet unknown principles underlying the functioning of living cells. At the same time, testable and predictive models of complex
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Programme: Independent Projects
Public web page: http://www.icysb.se/
Abstract (Expand)
Authors: Sofia Figueiredo, Theresa Kouril, Patrick Haferkamp, Patricia Wieloch, Dietmar Schomburg, Peter Ruoff, Bettina Siebers, Jörg Schaber, Esser D.
Date Published: 12th Jul 2017
Journal: PLoS One
Abstract (Expand)
Author: Schaber J.,Lapytsko A.,Flockerzi D.
Date Published: No date defined
Journal: J R Soc Interface
Abstract (Expand)
Author: Schaber J.,Baltanas R.,Bush A.,Klipp E.,Colman-Lerner A.
Date Published: 15th Nov 2012
Journal: Mol Syst Biol
