Tools: Chemical cross-linking, Site-directed mutagenesis, Membrane protein biochemistry, Biochemistry of substrate transport. molecular biological techniques (RNA/DNA techniques analyses of transport across cell membranes heterologous e..., Molecular Biology, Microbiology
I am a biologist by training. My research career is focussed on the structure-function relationships of membrane transport systems in Escherichia coli. I am interested in understanding the mechanism of ion and solute transport across the membrane and how this influences bacterial cell survival. My work mainly focusses on the ligand-gated potassium efflux systems which are crucial for cell survival during electrophile exposure and the mechanosensitive channels involved in hypoosmotic stress
I am postdoc in the group of Prof Ian Booth in Aberdeen working on the biochemical and biophysical characterisation of bacterial channels.
Tools: reporter gene analyses, site-directed and random mutagenesis, plasmon resonance spectroscopy, spectroscopy, molecular biological techniques (RNA/DNA techniques), Membrane protein biochemistry, Chromatography, Fermentation, Biochemistry and protein analysis, Genetics
I am a PhD student of the microbiology department at the Ludwig-Maximilians Universität München. I work at the chair of Prof. Kirsten Jung. The topic of our workpackage deals with "K+ homeostasis in Escherichia coli". In special I'm working on the sensor kinase KdpD that controls together with the response regulator KdpE the expression of the high-affinity K+ uptake system KdpFABC. The yet not fully understood molecular mechanism of stimulus perception and signal transduction is of particular