I'm a modeller, specialized in kinetic modeling of biochemical networks. My focus in the SysMO-LAB consortium is on creating models of Lactococcus lactis glycolysis and couple this to other related lactic acid bacteria like Streptococcus pyogenes and Enterococcus faecalis. Besides kinetic modeling, I'm also interested in combining various modeling techniques (genome-scale modeling, qualitative modeling).
SEEK ID: https://fairdomhub.org/people/52
Location:
Netherlands
ORCID: Not specified
Joined: 17th Feb 2009
Expertise: Bioinformatics, Mathematical modelling, Reactor models, dynamics of biological networks.
Tools: Molecular Biology, Cell biology, Computational and theoretical biology, Metabolomics, Model organisms, SBML, ODE, Partial differential equations, Algebraic equations, Linear equations, Copasi, JWS Online, Matlab, Mathematica, SQL, Material balance based modeling
Related items
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Comparative Systems Biology: Lactic Acid Bacteria
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=57
Global sensitivity analysis of a kinetic model to determine the sensitivities for each parameter, over a wide parameter range. We used the elementary effects method.
Submitter: Mark Musters
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Investigation of glycolysis and pyruvate branch...
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Lumped kinetic model of L. lactis glycolysis, formulated with ordinary differential equations. Simulations are in line with experimental data
Submitter: Mark Musters
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Investigation of glycolysis and pyruvate branch...
Organisms: Lactococcus lactis (batch)
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Here is a kinetic model (in COPASI format) of L. lactis glycolysis.
Creator: Mark Musters
Submitter: Mark Musters
Model type: Ordinary differential equations (ODE)
Model format: Copasi
Environment: Copasi
Organism: Lactococcus lactis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
SBML description of L. lactis glycolysis. Same as the uploaded Copasi file
Creator: Mark Musters
Submitter: Mark Musters
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Organism: Lactococcus lactis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The kinetic model includes sugar uptake, degradation of glucose into pyruvate and the fermentation of pyruvate.
Creators: Jennifer Levering, Mark Musters
Submitter: Jennifer Levering
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: JWS Online
Organism: Lactococcus lactis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Editor:
Date Published: 14th Feb 2012
Publication Type: Not specified
PubMed ID: 22325620
Citation: