I am working on a kinetic model of the central metabolism as well as on a genome wide model of Streptococcus pyogenes.
SEEK ID: https://fairdomhub.org/people/126
Location: Germany
ORCID: Not specified
Joined: 15th Sep 2009
Related items
- Programmes (1)
- Projects (1)
- Institutions (1)
- Studies (1)
- Assays (1)
- Models (4)
- Publications (1)
- Presentations (1)
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Comparative Systems Biology: Lactic Acid Bacteria
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=57
The reconstruction of the metabolic networks is done by sequence comparison with already annotated genomes of L. lactis, L. plantarum, B. subtilis and E. coli
Submitter: Jennifer Levering
Investigation: Investigation of glycolysis and pyruvate branch...
Assays: Genome-Scale Model Enterococcus faecalis V583, Genome-scale model of Streptococcus pyogenes
Snapshots: No snapshots
Metabolic network of S. pyogenes including primary metabolism, polysaccharide metabolism, purine and pyrimidine biosoynthesis, teichoic acid biosynthesis, fatty acid and phospholipid bioynthesis, amino acid metabolism, vitamins and cofactors
Submitter: Jennifer Levering
Biological problem addressed: Metabolic Network
Investigation: Investigation of glycolysis and pyruvate branch...
Organisms: Streptococcus pyogenes : M49 (591) (wild-type / wild-type)
Models: Genome-scale model of Streptococcus pyogenes
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Preliminary metabolic network of S. pyogenes including primary metabolism, polysaccharide metabolism, purine and pyrimidine biosoynthesis, teichoic acid biosynthesis, fatty acid and phospholipid bioynthesis, amino acid metabolism, vitamins and cofactors. The model still needs to be validated.
Creator: Jennifer Levering
Submitter: Jennifer Levering
Model type: Metabolic network
Model format: SBML
Environment: Not specified
Organism: Streptococcus pyogenes
Investigations: Investigation of glycolysis and pyruvate branch...
A reconstruction of the cellular metabolism of the opportunistic human pathogen Enterococcus faecalis V583 represented as stoichiometric model and analysed using constraint-based modelling approaches
Creators: Nadine Veith, Margrete Solheim, Koen van Grinsven, Jennifer Levering, Jeroen Hugenholtz, Helge Holo, Ingolf Nes, Bas Teusink, Ursula Kummer, Brett G Olivier, Ruth Grosseholz
Submitter: Nadine Veith
Model type: Linear equations
Model format: SBML
Environment: Not specified
Organism: Enterococcus faecalis
Investigations: Investigation of glycolysis and pyruvate branch...
The kinetic model includes sugar uptake, degradation of glucose into pyruvate and the fermentation of pyruvate.
Creator: Jennifer Levering
Submitter: Jennifer Levering
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: JWS Online
Organism: Streptococcus pyogenes
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
The kinetic model includes sugar uptake, degradation of glucose into pyruvate and the fermentation of pyruvate.
Creators: Jennifer Levering, Mark Musters
Submitter: Jennifer Levering
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: JWS Online
Organism: Lactococcus lactis
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Abstract (Expand)
Authors: N. Veith, M. Solheim, K. W. van Grinsven, B. G. Olivier, J. Levering, R. Grosseholz, J. Hugenholtz, H. Holo, I. Nes, B. Teusink, U. Kummer
Date Published: 19th Dec 2014
Publication Type: Not specified
PubMed ID: 25527553
Citation: Appl Environ Microbiol. 2015 Mar 1;81(5):1622-33. doi: 10.1128/AEM.03279-14. Epub 2014 Dec 19.
SysMO-LAB2 meeting in Copenhagen Nov 21-22, 2012
Creator: Jennifer Levering
Submitter: Jennifer Levering