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Web page: http://www.uni-heidelberg.de/index_e.html
Country: Germany
City: Heidelberg
Address:
University Heidelberg, IPMB
Im Neuenheimerfeld 364
Germany
Related items
Projects: SysVirDrug
Institutions: University of Heidelberg
Projects: SilicoTryp
Institutions: University of Heidelberg
Projects: SysMO-LAB
Institutions: University of Heidelberg
I am working on the development of algorithms for Comparative Systems Biology.
Projects: COVID-19 Disease Map
Institutions: University of Heidelberg
Projects: SilicoTryp
Institutions: University of Heidelberg
Expertise: network inference, motif detection
Tools: MySQL, HTML, Bioconductor Packages in R, Perl programming
Projects: SysMO-LAB
Institutions: Heidelberg Institute for Theoretical Studies (HITS gGmbH), University of Heidelberg
Projects: MESI-STRAT
Institutions: University of Heidelberg
Projects: COVID-19 Disease Map
Institutions: University of Heidelberg
Projects: MOSES
Institutions: University of Heidelberg
Projects: SilicoTryp
Institutions: University of Heidelberg
Expertise: Biochemistry
Tools: Biochemistry and protein analysis, enzyme kinetics, RNA interference
Professor of Biochemistry at the Centre of Biochemistry of Heidelberg University, teaching biochemistry for medical and biology students
Research focus is the trypanothione redox metabolism of African trypanosomes (Trypanosoma brucei).
The work is funded within the Collaborative Research Centre 544 on "Control of Tropical Infectious Diseases" of the German Research Foundation
Projects: SysMO-LAB, Kinetics on the move - Workshop 2016, de.NBI-SysBio
Institutions: University of Heidelberg
Ursula Kummer is heading the dept. "Modeling of Biological Processes" at the University of Heidelberg.
Projects: SilicoTryp
Institutions: University of Heidelberg
Projects: SysMO-LAB
Institutions: University of Heidelberg
I am working on a kinetic model of the central metabolism as well as on a genome wide model of Streptococcus pyogenes.
Projects: COMBINE Multicellular Modelling
Institutions: University of Heidelberg

Projects: COVID-19 Disease Map
Institutions: University of Heidelberg

Projects: Kinetics on the move - Workshop 2016, de.NBI-SysBio
Institutions: University of Heidelberg
Projects: MESI-STRAT
Institutions: University of Heidelberg
Projects: COVID-19 Disease Map
Institutions: University of Heidelberg
MESI-STRAT: Systems Medicine of Metabolic-Signaling Networks -A New Concept for Breast Cancer Patient Stratification.
Breast cancer is a complex disease with high prevalence in the European Union and world-wide. 75%-80 of the patients have estrogen receptor-positive (ER)-positive tumors and are treated with endocrine therapies. Endocrine therapies, which block ER-driven tumor growth, show high efficacy. Yet, a significant proportion of the patients will eventually relapse with metastatic breast
...
Programme: This Project is not associated with a Programme
Public web page: http://www.mesi-strat.eu
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus
Here we share resources and best practices to develop a disease map for COVID-19. The project is progressing as a broad community-driven effort. We aim to establish a knowledge repository on virus-host interaction mechanisms specific to the SARS-CoV-2. The COVID-19 Disease Map is an assembly of molecular interaction diagrams established based on literature evidence.
Programme: Disease Maps
Public web page: http://doi.org/10.17881/covid19-disease-map
Programme: FAIR Biocatalysis
Public web page: Not specified
Organisms: Not specified
Programme: FAIR Biocatalysis
Public web page: Not specified
Organisms: Not specified
Programme: FAIR Biocatalysis
Public web page: Not specified
Organisms: Not specified
Programme: COMBINE (Computational Modeling in Biology Network)
Public web page: https://multicellml.org/
Organisms: Not specified
The aim of the project is bioprospecting, isolation and characterization of novel secondary metabolites, produced by extremophilic microorganisms. The project is dedicated to a poorly investigated problem of antagonistic interactions between extremophilic microorganisms in their communities, namely, to the investigation of the ability of extremophiles to produce secondary metabolites with biocidic, cytotoxic and cytostatic activities. Working out this problem will fulfill an important applied
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Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: Not specified
Organisms: Not specified
The Systems Biology Service Center of de.NBI (de.NBI-SysBio) provides bioinformatics support and a standards-based data management for systems biology projects, with focus on the provenance of experimental results and on the reproducibility of modeling experiments, as well as high-quality curated biochemical data to modelers and experimentalists.
The node concentrates on two tools for the data management in life sciences research: SEEK, a catalogue for storage, registration and exchange of data
...
Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: Not specified
Organisms: Not specified
Translating Systems Virology data into broad-spectrum antiviral Drugs
Programme: ERASysAPP
Public web page: Not specified
The workshop focuses on the publication, curation, retrieval, and usage of kinetic data from the reaction kinetics database SABIO-RK and on the use of data in modeling. There will be experience reports from scientists who successfully used experimental data to formulate or verify biological hypotheses with the computer, and you will experience how experimental data can be used with computational models.
Programme: de.NBI Systems Biology Service Center (de.NBI-SysBio)
Public web page: http://www.h-its.org/event/kinetics-on-the-move/
Comparative Systems Biology: Lactic Acid Bacteria
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=57
MOSES (Micro Organism Systems biology: Energy and Saccharomyces cerevisiae) develops a new Systems Biology approach, which is called 'domino systems biology'. It uses this to unravel the role of cellular free energy ('ATP') in the control and regulation of cell function. MOSES operates though continuous iterations between partner groups through a new systems-biology driven data-management workflow. MOSES also tries to serve as a substrate for three or more other SYSMO programs.
Programme: SysMO
Public web page: http://www.moses.sys-bio.net/
Organisms: Saccharomyces cerevisiae
The SilicoTryp project aims at the creation of a “Silicon Trypanosome”, a comprehensive, experiment-based, multi-scale mathematical model of trypanosome physiology.
Trypanosomes are blood-stream parasites transmitted by tsetse flies; they cause African sleeping sickness in humans and livestock. Currently available drugs have severe side effects, and the parasites are rapidly developing resistance.
In this project, we collect a wide range of new experimental data on the parasite in its various
...
Programme: SysMO
Public web page: http://silicotryp.ibls.gla.ac.uk/wiki/Main_Page
Organisms: Trypanosoma brucei