Professor of Biochemistry at the Centre of Biochemistry of Heidelberg University, teaching biochemistry for medical and biology students Research focus is the trypanothione redox metabolism of African trypanosomes (Trypanosoma brucei). The work is funded within the Collaborative Research Centre 544 on "Control of Tropical Infectious Diseases" of the German Research Foundation
SEEK ID: https://fairdomhub.org/people/337
Location: Germany
ORCID: Not specified
Joined: 2nd Sep 2010
Expertise: Biochemistry
Tools: Biochemistry and protein analysis, enzyme kinetics, RNA interference
Related items
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
The SilicoTryp project aims at the creation of a “Silicon Trypanosome”, a comprehensive, experiment-based, multi-scale mathematical model of trypanosome physiology. Trypanosomes are blood-stream parasites transmitted by tsetse flies; they cause African sleeping sickness in humans and livestock. Currently available drugs have severe side effects, and the parasites are rapidly developing resistance. In this project, we collect a wide range of new experimental data on the parasite in its various ...
Programme: SysMO
Public web page: http://silicotryp.ibls.gla.ac.uk/wiki/Main_Page
Organisms: Trypanosoma brucei
This is a protocol for determining the activity of the T. brucei Trypanothione synthetase under in vivo-like conditions.
Creators: Alejandro Leroux, Luise Krauth-Siegel
Submitter: Alejandro Leroux
This method describes the preparation of the in vivo-like buffer for the measurement of bloodstream T. brucei recombinant enzymes under pseudo-physiological conditions.
Creators: Alejandro Leroux, Luise Krauth-Siegel
Submitter: Alejandro Leroux
Abstract (Expand)
Authors: , , , , , , T. Papamarkou, , , , , , , ,
Date Published: 7th May 2014
Publication Type: Not specified
PubMed ID: 24797926
Citation:
Abstract (Expand)
Authors: , , , , , , Paul A M Michels, ,
Date Published: 6th May 2010
Publication Type: Not specified
PubMed ID: 20444304
Citation:
Poster presented during the ICSB 2011 conference in Mannheim
Creators: Alejandro Leroux, Luise Krauth-Siegel
Submitter: Alejandro Leroux