Fiona Achcar
SEEK ID: https://fairdomhub.org/people/347
Location:
United Kingdom
ORCID: Not specified
Joined: 9th Sep 2010
Expertise: Not specified
Tools: Not specified
Their tagsRelated items
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
The SilicoTryp project aims at the creation of a “Silicon Trypanosome”, a comprehensive, experiment-based, multi-scale mathematical model of trypanosome physiology. Trypanosomes are blood-stream parasites transmitted by tsetse flies; they cause African sleeping sickness in humans and livestock. Currently available drugs have severe side effects, and the parasites are rapidly developing resistance. In this project, we collect a wide range of new experimental data on the parasite in its various ...
Programme: SysMO
Public web page: http://silicotryp.ibls.gla.ac.uk/wiki/Main_Page
Describes the assumptions made, how to integrate the new reactions to the rest of the glycolysis model, the parameters needed and the preliminary parameter values collected from the litterature.
Creator: Fiona Achcar
Submitter: Fiona Achcar
SBML models without activity of the glycolytic enzymes in the cytosol:
Glycolysis_noActivityInCytosol_1a.xml Model 1a Glycolysis_noActivityInCytosol_1b.xml Model 1b Glycolysis_noActivityInCytosol_2.xml Model 2 Glycolysis_noActivityInCytosol_3.xml Model 3 Glycolysis_noActivityInCytosol_4.xml Model 4 Glycolysis_noActivityInCytosol_5.xml Model 5 Glycolysis_noActivityInCytosol_6.xml Model 6
SBML models with activity of the glycolytic enzymes in the cytosol:
Glycolysis_withActivityInCytosol_1a.xm Model ...
Creator: Fiona Achcar
Submitter: Fiona Achcar
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
DownloadFirst darft of a model including glycolysis and the transcription and translation of the enzymes. See the datafile "Information on the darft transcription/translation model." for information.
Creator: Fiona Achcar
Submitter: Fiona Achcar
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Fixed parameter model, where the glycolysis model of bloodstream form T. brucei is extended with the pentose phosphate pathway and a ribokinase in the glycosome. Non-final version.
Creators: Eduard Kerkhoven, Fiona Achcar
Submitter: Eduard Kerkhoven
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Copasi
Fixed parameter model, where the glycolysis model of bloodstream form T. brucei is extended with the pentose phosphate pathway and an ATP:ADP antiporter over the glycosomal membrane. Non-final version.
Creators: Eduard Kerkhoven, Fiona Achcar
Submitter: Eduard Kerkhoven
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: JWS Online
SBML file supplementary material of the publication.
Creators: Fiona Achcar, Barbara Bakker, Mike Barrett, Rainer Breitling, Eduard Kerkhoven
Submitter: Fiona Achcar
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Abstract (Expand)
Authors: , , , , , , T. Papamarkou, , , , , , , ,
Date Published: 7th May 2014
Publication Type: Not specified
Abstract (Expand)
Authors: , , V. P. Alibu, R. J. Burchmore, I. H. Gilbert, M. Trybilo, N. N. Driessen, D. Gilbert, , ,
Date Published: 5th Dec 2013
Publication Type: Not specified
Abstract (Expand)
Editor:
Date Published: 19th Jan 2012
Publication Type: Not specified
