Model of Trypanosoma brucei glycolysis as published in Achcar et al. (2012).

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I am an Associate Professor in Systems Biology and the University Medical Centre Groningen. My research aims at understanding how energy metabolism is integrated and regulated. My work includes experimental, modelling as well as theoretical research. Recently I studied how metabolic regulation and gene-expression regulation work together towards in integrated response, e.g. when parasites are confronted with chemical inhibitors. Much of my work has been about the regulation of glycolysis and its
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I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at
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