Kinetic understanding of the T. brucei trypanothione synthesis pathway

Aim. To provide critical quantitative parameter information and to model redox balance by determining the cellular concentration of all enzymes involved in the trypanothione-dependent hydroperoxide detoxification system of trypanosomes and by performing the kinetic characterization of the involved enzymes under pseudo-physiological conditions.

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Created: 18th Jun 2012 at 17:32

Last updated: 31st Jul 2014 at 10:10

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