Katja Bettenbrock

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About Katja Bettenbrock:

I am interested in the coupling of global regulation and metabolism in E. coli. To analyze this I construct and analyze defined mutant strains. These strains are characterized in bioreactor experiments of different types (batch, conti, pulse ...) and measurements on the level of metabolites, mRNA, and protein are applied. For all projects there are cooperation partners that use the data in modeling approaches either from the MPI Magdeburg or from the SUMO consortium.

SEEK ID: https://fairdomhub.org/people/31

Location: Germany

ORCID: Not specified

Joined: 4th May 2009

Expertise: Microbiology, Genetics, Molecular Biology, Regulatory Networks

Tools: Mutant and Strain Construction; RNA / DNA Techniques; RT-RealTime-PCR; 2D-Gels; Metabolite Analysis; Bioreactor Experiments; Flow Cyometry; ...

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Model repository for M4 (Make Me My Model) clients of ISBE

ISBE-Light provides M4 service (Make Me My Mode) where non modelers can request (assistance with) the making of a computational model of their biological system. These models are deposited here.

Web page: http://www.isbe.nl

SysMO

SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".

The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.

Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...

Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep

Web page: http://sysmo.net/

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EraCoBiotech 2 nd call proposal preparation

Glycon proposal preparation

Programme: Model repository for M4 (Make Me My Model) clients of ISBE

Public web page: Not specified

Organisms: Sulfobacillus thermosulfidooxidans

SUMO

"Systems Understanding of Microbial Oxygen responses" (SUMO) investigates how Escherichia coli senses oxygen, or the associated changes in oxidation/reduction balance, via the Fnr and ArcA proteins, how these systems interact with other regulatory systems, and how the redox response of an E. coli population is generated from the responses of single cells. There are five sub-projects to determine system properties and behaviour and three sub-projects to employ different and complementary modelling ...

Programme: SysMO

Public web page: http://www.sysmo.net/index.php?index=55

Organisms: Escherichia coli, Escherichia coli K-12

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Max Planck Institute for Dynamics of Complex Technical Systems

Country: Germany

City: Magdeburg

Web page: http://www.mpi-magdeburg.mpg.de

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Analysis of population heterogeneity in chemostat cultures with limited oxygen supply

SUMO

Cultures grown under standard SUMO conditions were analyzed with respect to heterogeneity in gene expression. To this end GFP reporter strains were constructed and GFP expression at single cell level was monitored by flow cytometry.