PtsG, Mal

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Name: PtsG, Mal

Provider's strain ID: Not specified

Provider Name: Not specified

Synonym: Not specified

Comment: Not specified

Genotypes del ptsG;del malEFG

Phenotypes: wild-type

Organism: Escherichia coli K-12

Activity

Views: 2550

Created: 14th Aug 2014 at 11:25

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Katja Bettenbrock

Projects: SUMO, EraCoBiotech 2 nd call proposal preparation

Institutions: Max Planck Institute for Dynamics of Complex Technical Systems

Expertise: Microbiology, Genetics, Molecular Biology, Regulatory Networks

Tools: Mutant and Strain Construction; RNA / DNA Techniques; RT-RealTime-PCR; 2D-Gels; Metabolite Analysis; Bioreactor Experiments; Flow Cyometry; ...

I am interested in the coupling of global regulation and metabolism in E. coli. To analyze this I construct and analyze defined mutant strains. These strains are characterized in bioreactor experiments of different types (batch, conti, pulse ...) and measurements on the level of metabolites, mRNA, and protein are applied. For all projects there are cooperation partners that use the data in modeling approaches either from the MPI Magdeburg or from the SUMO consortium.

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SysMO

SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".

The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.

Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...

Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep

Web page: http://sysmo.net/

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SUMO

"Systems Understanding of Microbial Oxygen responses" (SUMO) investigates how Escherichia coli senses oxygen, or the associated changes in oxidation/reduction balance, via the Fnr and ArcA proteins, how these systems interact with other regulatory systems, and how the redox response of an E. coli population is generated from the responses of single cells. There are five sub-projects to determine system properties and behaviour and three sub-projects to employ different and complementary modelling ...

Programme: SysMO

Public web page: http://www.sysmo.net/index.php?index=55

Organisms: Escherichia coli, Escherichia coli K-12