Consortium of European research groups that aim to develop - in the forthcoming 10 years - a cluster of interlinked models that describe the whole-body human energy metabolism and its multi-dimensional regulation. Regulation includes interations with the brain, the immune system and the gut.
Web page: Not specified
Funding details:no funding yet
Related items
Projects: HUMET Startup
Institutions: University of Gothenburg
https://orcid.org/0000-0003-0786-8091Expertise: experiments, lipdomics, mouse studies, Kinetics
Tools: stable isotopes, lipidomics
POSITION: Professor of Cardiovascular Research at University of Gothenburg, chair of Dept of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, and part-time physician at Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
RESEARCH: My main long-term interest has been to understand the underlying mechanisms that lead to, and consequences of, lipid accumulation in the liver, arterial wall and heart, with the goal of translating this knowledge into ...
Projects: HUMET Startup
Institutions: Université catholique de Louvain
https://orcid.org/0000-0003-2040-2448Expertise: Gut microbiota, Akkermansia muciniphila, Obesity, diabetes, Endocannabinoid system, Cell specific KO, Innate immunity, Prebiotics, Probiotics, Insulin resistance, Inflammation
Tools: Animal models, Genetic modification, Microbiology, Integrative physiology, Glucose metabolism, Lipid metabolism, Molecular biology techniques (RNA/DNA/Protein), LPS measurments, Gut microbiota analysis
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research and group leader in the Metabolism and Nutrition lab at the Louvain Drug Research Institute from the UCL, Brussels, Belgium. He is WELBIO investigator and recipient of an ERC Starting Grant 2013 and a PoC ERC Grant 2016. He is laureate of the Baillet-Latour grant for medical research and the international prize of Physiology Lucien Dautrebande. His main research interests are the investigation of interactions ...
Projects: COSMIC, SysMO-LAB, HUMET Startup
Institutions: Wageningen University & Research
Expertise: nuclear receptors, metabolic homeostasis
Tools: Transcriptomics, metabolic phenotyping, ChIP-seq, Data Integration
Position : Professor, Centre of Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne
My research interests focus on understanding metabolic homeostasis. We are mainly using genetically modified mouse models and systems approaches. I am also very keen in exploring how Omics approaches is changing, or not changing, key biological concepts. Link to complete publication list : http://orcid.org/0000-0001-5483-288X
Projects: HUMET Startup, COVID-19 Disease Map
Institutions: Bilkent University
https://orcid.org/0000-0002-7153-0784Expertise: Bioinformatics, Systems Biology, SBGN standard, Network Visualization, Graphical Editors
Tools: SBGNViz, cBioPortal, PathwayMapper, ChiBE, Newt Editor
Projects: HUMET Startup, COVID-19 Disease Map
Institutions: Centro de Investigación Príncipe Felipe, Fundación Progreso y Salud
https://orcid.org/0000-0003-3318-120XExpertise: Bioinformatics, Data Management, Mathematical modelling, Genomics, Genetics, Transcriptomics, Systems Biology, Microarray analysis, Data Integration
Tools: Bioinformatics, Computational and theoretical biology, Computational Systems Biology, Data Management, Databases, Dynamic modelling, Genetics, Genomics, R, Systems Biology, Transcriptomics, Java
My scientific interests revolve around functional genomics, systems biology and the development of algorithms and software for the analysis of high-throughput data (mainly, but not restricted to, Next Generation Sequencing) and its application to the relationship between genotype and phenotype, mainly oriented to personalized and precision medicine. I am especially interested in the study of disease mechanisms and drug action mechanisms, drug repositioning and the definition of mechanism-based ...
Projects: HUMET Startup
Institutions: Universitair ziekenhuis Antwerpen
https://orcid.org/0000-0002-7527-4714Expertise: Hepatology, Non-alcoholic fatty liver disease
Sven Francque is currently Head of the Department of Gastroenterology and Hepatology of the Antwerp University Hospital and full professor of gastroenterology and hepatology at the University of Antwerpen, with a longtanding interest and expertise in the field of Non-Alcohloic Fatty Liver Disease. In collaboration with the Department of Endocrinology, Diabetes and Metabolic Diseases, a large cohort of well-phenotyped patients has been built up.
Expertise: Metabolic Control Analaysis, Metabolomics, Metabolic Networks
Tools: Metabolomics, Transcriptomics
POSITION Professor of Systems Medicine/Biology at the Academic Medical Center, Amsterdam and University Medical Center Groningen, Groningen, The Netherlands
RESEARCH My major projects focus on understanding the etiology of metabolic syndrome and its comorbidities type2 diabetes and cardiovascular disease. To get grip on the sequence of events in disease progression we make use of longitidunal models and apply multiscal systems biology approaches.
PUBLICATIONS
My published work can be found at: ...
Projects: HUMET Startup
Institutions: University Medical Center Hamburg - Eppendorf Hamburg
Expertise: Lipids, metabolism, Metabolic Models, mouse studies
Expert in lipid metabolism and adipose tissue
Projects: HUMET Startup
Institutions: University of Amsterdam
Expertise: neuroanatomy, endocrinology, chronobiology
POSITION Professor of Experimental Neuroendocrinology at the Academic Medical Center (AMC) and the Hypothalamic Integration Mechanisms group at the Netherlands Institute for Neuroscience (NIN), Amsterdam, The Netherlands RESEARCH My major projects focus on understanding how the hypothalamic biological clock controls hormonal rhythms and energy metabolism. For this we mainly use the rat as an animal model. Important techniques include blood sampling from and targeted brain infusions in awake and ...
Projects: HUMET Startup, EraCoBiotech 2 nd call proposal preparation, COVID-19 Disease Map
Institutions: geneXplain GmbH
https://orcid.org/0000-0001-6775-2467Expertise: Systems Biology, promoters and anhancers, gene regulation, signal transduction, drug targets
Tools: geneXplain platform, BioUML, R, c++
Alexander Kel received his Ph.D. in Bioinformatics, Molecular Biology and Genetics in 1990. He studied biology and mathematics at Novosibirsk State University and obtained his M.S. in biology with special focus on mathematical biology in 1985. He worked for 15 years at the Institute of Cytology and Genetics, Russia (ICG) holding positions as a programmer, scientist, senior scientist and Vice-Head of the Laboratory of Theoretical Molecular Genetics. In 1995, he won the Academician Belaev Award. ...
Projects: HUMET Startup
Institutions: Wageningen University & Research
https://orcid.org/0000-0003-4488-7734Expertise: Lipids, Nutrition, metabolism, nuclear receptors
Tools: Microarray analysis, Molecular Biology, Cell and tissue culture
Dr. Sander Kersten received his PhD in Nutritional Biochemistry from Cornell University in 1997. After a postdoctoral stay in the laboratory of Dr. Walter Wahli at the University of Lausanne, Switzerland, he moved to Wageningen in 2000, initially as a fellow of the Royal Netherlands Academy of Arts and Sciences and later as Associate Professor. Since 2011 he is Full Professor in Molecular Nutrition and since 2014 chair of the Nutrition, Metabolism and Genomics group. His current research interests ...
Projects: TRANSLUCENT, HUMET Startup
Institutions: Humboldt-Universität zu Berlin, Humboldt University Berlin
Projects: PSYSMO, DigiSal, GenoSysFat, HUMET Startup, EmPowerPutida, MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine, SAFE-Aqua, INDIE - Biotechnological production of sustainable indole
Institutions: Helmholtz Centre for Infection Research Braunschweig, Wageningen University & Research
Expertise: Microbiology, Mathematical modelling of biosystems and bioprocesses, Optimal experimental design, Systems Biology, Biotechnology
Tools: Bioinformatics, Genetic modification, Proteomics, Fermentation, Microarray analysis, Computational Systems Biology, Metabolic Engineering, microbiology techniques, reverse engineering, computational platform development, metabolic netwlrk visualization
My research activities has been to use mathematical models and Computational Biology to answer biological questions, intertwining in silico and experimental methods at all stages. I have a strong interest in exploring the interfaces between Fundamental Biology and bona fide Engineering, specifically in the realm of environmental and industrial problems. The research goals of my group are to contribute to the elucidation of mechanisms underlying basic cellular processes, evolution and ecological ...
Projects: HUMET Startup, COVID-19 Disease Map, C19DM-Neo4j
Institutions: European Institute for Systems Biology and Medicine, Luxembourg Centre for Systems Biomedicine (LCSB)
https://orcid.org/0000-0001-7137-4171Expertise: Systems Biology, Systems Medicine, Disease Maps, Systems Biology Graphical Notation
Tools: SBGN, CellDesigner, SBGN-ED, Newt Editor
Projects: HUMET Startup
Institutions: AstraZeneca
Aim of HUMET Startup Project is to make an inventory of expertise, research goals, resources etc. of the HUMET Coaliytion of the Willing.
Programme: HUMET
Public web page: Not specified
Organisms: Homo sapiens
List of publications from 2006 till 2016. Note: I retired from the University of Amsterdam in 2010
Creator: Roel Van Driel
Submitter: Roel Van Driel
Investigations: No Investigations
Studies: No Studies
Assays: No Assays