IMPAcTB
OverviewProgramme: IMPAcTB
SEEK ID: https://fairdomhub.org/projects/222
Public web page: Not specified
Organisms: No Organisms specified
FAIRDOM PALs: No PALs for this Project
Project created: 13th Jan 2021
Related items
Projects: IMPAcTB, MIT SRP, MetNet, Endometriosis
Institutions: Massachusetts Institute of Technology
Projects: IMPAcTB, MIT SRP, MetNet
Institutions: Massachusetts Institute of Technology
Projects: MIT SRP, IMPAcTB, MetNet
Institutions: Massachusetts Institute of Technology
https://orcid.org/0000-0001-7363-562X
Institutions: Massachusetts Institute of Technology
Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology
Institutions: Massachusetts Institute of Technology
Projects: IMPAcTB
Web page: https://www.niaid.nih.gov/research/immune-mechanisms-protection-mycobacterium-tuberculosis
Submitter: Dikshant Pradhan
Studies: Fc-FcγR interactions shift alveolar macrophage metabolism to promote Myc..., Fc-engineered antibodies leverage neutrophils to drive control of Mycoba..., Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resis..., Multimodal profiling of lung granulomas in macaques reveals cellular cor..., Robust IgM responses following intravenous vaccination with Bacille Calm..., T cell signatures of bacterial control among M. tuberculosis 'resisters'
Assays: Anti-Microbial Assay – Metadata, Flow Cytometry - Data Linked, Flow Cytometry Analysis - Data Linked, Flow Cytometry Processing – Data Attached, Flow Cytometry – Data Linked, Functional Assay – Metadata, Immunohistochemistry – Data Linked, Library Creation – Metadata, Luminex Assay – Metadata, Luminex Data Processing – Data Attached, NHP Necropsy – Metadata, NHP Tissue Collection – Metadata, PET-CT Scan Analysis – Data Linked, PET-CT Scan – Data Linked, Patient Visit - Metadata, Patient Visit – Metadata, Patient Visit – Metadata, Single Cell Clustering Analysis – Data Linked, Single Cell Expression Matrix Analysis – Data Linked, Single Cell Sequencing Analysis – Data Linked, Single Cell Sequencing – Data Linked, Single Cell Sequencing – Data Linked, Tissue Collection - Metadata, Tissue Collection - Metadata, Tissue Extraction – Metadata
Hannah P.Gideon, Travis K.Hughes, Constantine N.Tzouanas, Marc H.WadsworthII, Ang AndyTu, Todd M.Gierahn, Joshua M.Peters, Forrest F.Hopkins, Jun-RongWei, Conner Kummerlowe, Nicole L.Grant, Kievershen Nargan, Jia YaoPhuah, H. JacobBorish, Pauline Maiello, Alexander G.White, Caylin G.Winchell, Sarah K.Nyquist, Sharie Keanne C.Ganchua, Amy Myers, Kush V.Patel, Cassaundra L.Ameel, Catherine T.Cochran, Samira Ibrahim, Jaime A.Tomko, Lonnie JamesFrye, Jacob ...
Submitter: Dikshant Pradhan
Investigation: IMPAcTB
Assays: Immunohistochemistry – Data Linked, Library Creation – Metadata, NHP Necropsy – Metadata, PET-CT Scan Analysis – Data Linked, PET-CT Scan – Data Linked, Patient Visit – Metadata, Single Cell Clustering Analysis – Data Linked, Single Cell Expression Matrix Analysis – Data Linked, Single Cell Sequencing – Data Linked
Meng Sun*, Jolie M. Phan*, Nathan S. Kieswetter, Krystle K.Q. Yu, Malisa T. Smith, Huang Huang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W. Henry Boom, Thomas R. Hawn, Catherine M. Stein, Harriet Mayanja-Kizza, Mark M. Davis*, Chetan Seshadri*
Abstract: A subset of individuals with a high probability of exposure to M. tuberculosis (M.tb) ...
Submitter: Charles Demurjian
Investigation: IMPAcTB
Assays: Flow Cytometry - Data Linked, Flow Cytometry Analysis - Data Linked, Patient Visit - Metadata, Tissue Collection - Metadata
Thiel BA, Worodria W, Nalukwago S, Nsereko M, Sanyu I, Rejani L, Zawedde J, Canaday DH, Stein CM, Chervenak KA, Malone LL, Kiyemba R, Silver RF, Johnson JL, Mayanja-Kizza H, Boom WH. Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resist versus those who develop latent Mycobacterium tuberculosis infection. PLoS One. 2021 Apr 9;16(4):e0249477. doi: 10.1371/journal.pone.0249477. PMID: 33836031; PMCID: PMC8034721.
Abstract: ...
Submitter: Dikshant Pradhan
Investigation: IMPAcTB
Assays: Flow Cytometry Processing – Data Attached, Flow Cytometry – Data Linked, Patient Visit – Metadata, Tissue Collection - Metadata
Submitter: Dikshant Pradhan
Investigation: IMPAcTB
Assays: Single Cell Sequencing Analysis – Data Linked, Single Cell Sequencing – Data Linked, Tissue Extraction – Metadata
Edward B. Irvine, Joshua M. Peters, Richard Lu, Patricia S. Grace, Jaimie Sixsmith, Aaron Wallace, Matthew Schneider, Sally Shin, Wiktor Karpinski, Jeff C. Hsiao, Esther van Woudenbergh, Arturo Casadevall, Bryan D. Bryson, Lisa Cavacini, View ORCID ProfileGalit Alter, Sarah M. Fortune doi: https://doi.org/10.1101/2022.05.01.490220
Novel vaccination and therapeutic strategies are urgently needed to mitigate the tuberculosis (TB) epidemic. While extensive efforts have focused on potentiating ...
Development of an effective tuberculosis (TB) vaccine has suffered from an incomplete understanding of the correlates of protection against Mycobacterium tuberculosis (Mtb). Intravenous (i.v.) vaccination with Bacille Calmette–Guérin (BCG) provides nearly complete protection against TB in rhesus macaques, but the antibody response it elicits remains incompletely defined. Here we show that i.v. BCG drives superior antibody responses in the plasma and the lungs of rhesus macaques compared to ...
Submitter: Dikshant Pradhan
Investigation: IMPAcTB
Assays: Anti-Microbial Assay – Metadata, Functional Assay – Metadata, Luminex Assay – Metadata, Luminex Data Processing – Data Attached, NHP Tissue Collection – Metadata
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Dikshant Pradhan
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Jake Schissel
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: IMPAcTB
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
DownloadBatch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Dikshant Pradhan
Submitter: Dikshant Pradhan
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Jake Schissel
Submitter: Jake Schissel
Creators: None
Submitter: Jake Schissel
Batch sample publishing
Creators: None
Submitter: Jake Schissel
Creators: None
Submitter: Jake Schissel
Creators: None
Submitter: Jake Schissel
Creators: None
Submitter: Jake Schissel
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Charles Demurjian
Submitter: Charles Demurjian
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Jake Schissel
Submitter: Jake Schissel
Creator: Dikshant Pradhan
Submitter: Dikshant Pradhan
Creator: Dikshant Pradhan
Submitter: Dikshant Pradhan
JP
UID (Text) *, Name (Text) , ID (Text) , Age (Text) , Sex (Text) , StatusHIV (Text) , Contact (Text) , SubjectLocation (Text) , Scientist (Text) , Scarring (Text) , Height (Text) , HeightUnits (Text) , Weight (Text) , WeightUnits (Text) , Study (Text) , BaselineCohort (Text)
Not specified
JP
UID (Text) *, File_PrimaryData (Text) , Link_PrimaryData (Text) , Scientist (Text) , Parent (Text)
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UID (Text) *, Name (Text) , Parent (Text) , Scientist (Text)
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JP
UID (Text) *, Name (Text) , Catalog# (Text) , Vendor (Text) , Analyte (Text) , Clone (Text) , Fluorophore (Text) , ExperimentType (Text) , CatalogLink (Text)
Not specified
JP
UID (Text) *, Name (Text) , Scientist (Text) , SampleCreationDate (Text) , Protocol (Text) , Parent (Text) , Type (Text) , OrganDetail (Text) , StorageSite (Text) , StorageLocation (Text) , CellCount (Text)
Not specified
Boom 2.0
UID (Text) *, File_PrimaryData (Text) , Link_PrimaryData (Text) , Checksum_PrimaryData (Text) , Scientist (Text) , Parent (Text) , Protocol (Text) , Software (Text)
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BOOM 2.0
UID (Text) *, File_PrimaryData (Text) , Link_PrimaryData (Text) , Scientist (Text) , SampleCreationDate (Text) , Parent (Text) , Protocol (Text) , Instrument (Text) , Checksum_PrimaryData (Text) , AntibodyParent (Text) , CompensationFCSParent (Text) , Repository (Text) , RepositoryID (Text)
Not specified
ABP Boom 2.0
UID (Text) *, Name (Text) , Parent (Text)
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Boom
UID (Text) *, File_PrimaryData (Text) , Link_PrimaryData (Text) , Parent (Text) , Scientist (Text) , Checksum_PrimaryData (Text) , Repository (Text) , RepositoryID (Text)
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BOOM
UID (Text) *, Name (Text) , Catalog# (Text) , Vendor (Text) , Analyte (Text) , Fluorophore (Text) , Clone (Text) , ExperimentType (Text) , Panel (Text)
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TIS Boom 2.0
UID (Text) *, Name (Text) , Type (Text) , Parent (Text) , SampleCreationDate (Text) , Organ (Text) , OrganDetail (Text) , Scientist (Text) , Protocol (Text) , StorageSite (Text) , StorageLocation (Text) , BALCollectedVolume (Text) , BALCollectedVolumeUnits (Text) , BALInstilledVolume (Text) , BALInstilledVolumeUnits (Text) , CellCount (Text)
Not specified
PAV Boom 2.0
UID (Text) *, Name (Text) , Scientist (Text) , SampleCreationDate (Text) , Type (Text) , Procedure (Text) , Protocol (Text) , Parent (Text) , ExperimentalTimepoint (Text) , VisitFacility (Text) , VisitLocation (Text) , TestType (Text) , TestResult (Text) , TestResultFile (Text) , Classification (Text)
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PAT Boom lab 2.0
UID (Text) *, Name (Text) , Scientist (Text) , Contact (Text) , ID (Text) , Age (Text) , Sex (Text) , SubjectLocation (Text) , Height (Text) , HeightUnits (Text) , Weight (Text) , WeightUnits (Text) , Study (Text) , BaselineCohort (Text) , Scarring (Text) , StatusHIV (Text)
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UID (Text) *, Name (Text) *, Scientist (Text) , Protocol (Text) , Type (Text) , Parent (Text) , VisitFacility (Text) , SampleCreationDate (Date) , Treatment1 (Text) , Treatment1Type (Text) , Treatment1Route (Text) , Treatment1Dose (Real number) , Treatment1DoseUnits (Text) , Procedure (Text)
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UID (Text) *, Name (Text) , Parent (Text) , Protocol (Text) , Scientist (Text)
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UID (Text) *, Name (Text) , Catalog# (Text) , Vendor (Text) , Analyte (Text) , Clone (Text) , Reporter (Text) , RRID (Text)
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UID (Text) *, File_PrimaryData (Text) , Link_PrimaryData (Text) , Checksum_PrimaryData (Text) , Lab (Text) , Scientist (Text) , Software (Text) , Parent (Text)
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UID (Text) *, File_PrimaryData (Text) , Link_PrimaryData (Text) , Scientist (Text) , Protocol (Text) , Parent (Text) , Instrument (Text) , Instrument2 (Text)
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UID (Text) *, Name (Text) , File_PrimaryData (Text) , Link_PrimaryData (Text) , SampleCreationDate (Date) , DataType (Text) , Protocol (Text) , Parent (Text) , Scientist (Text) , Lab (Text) , Checksum_PrimaryData (Text) , Software (Text)
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UID (Text) *, Name (Text) , File_PrimaryData (Text) , Link_PrimaryData (Text) , SampleCreationDate (Text) , Scientist (Text) , DataType (Text) , Barcodes (Text) , BarcodesDataType (Text) , Genes (Text) , GenesDataType (Text) , Metadata (Text) , MetadataDataType (Text) , Protocol (Text) , Parent (Text) , Lab (Text) , Repository (Text) , Accession (Text) , Checksum_PrimaryData (Text) , Checksum_Barcodes (Text) , Checksum_Genes (Text) , Checksum_Metadata (Text)
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