IMPAcTB

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SEEK ID: https://fairdomhub.org/investigations/438

Projects: Hi-IMPAcTB

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Creators and Submitter

Creator

Dikshant Pradhan

Submitter

Dikshant Pradhan

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Created: 14th Jan 2021 at 15:10

Last updated: 18th Oct 2021 at 14:05

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People (1)
Programmes (1)
Projects (1)
Studies (22)
Assays (172)
Data files (250+1)
SOPs (104)
Samples (31726)

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Dikshant Pradhan

Projects: Hi-IMPAcTB, MIT SRP

Institutions: Massachusetts Institute of Technology

Researcher at BioMIcro Center, Data Management and Analysis Core; Massachusetts Institute of Technology

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NExtSEEK

No description specified

Projects: MIT SRP, Hi-IMPAcTB, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC), Shoulders Lab

Web page: https://nextseek.mit.edu/

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Hi-IMPAcTB

About

This project houses all the publicly available datasets generated by the Hi-IMPAcTB consortium over the course of its 7+ years.

What is Hi-IMPAcTB?

Hi-IMPAcTB is an ambitious endeavor bringing together a team of international, interdisciplinary researchers to improve our understanding of host-pathogen interactions in the context of tuberculosis (TB). Funded by a multi-center contract from the NIH, the long-term goal of the consortium is to enable principled vaccine design by improving ...

Programme: NExtSEEK

Public web page: https://grantome.com/grant/NIH/75N93019C00071-0-9999-1

Organisms: Mus musculus, Homo sapiens, Macaca fascicularis, Macaca mulatta

Showing 20 out of a possible 22 Studies Advanced Studies list for this Investigation with search and filtering

BCG vaccination elicits protection against Mtb infection mediated by two phases of T cell immunity

Hi-IMPAcTB

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Charles Demurjian

Abiola F. Ogunsola, Rocky Lai, Kelly Cavallo, Gillian L. Beamer, and Samuel M. Behar

DOI:

Abstract: Vaccine development for tuberculosis is a global priority. Our studies using Collaborative Cross (CC) mice show that genetic diversity influences the efficacy of BCG, the most widely used TB vaccine. BCG vaccination of CC042 mice reduces their lung bacillary burden and increases their survival following low-dose aerosol Mycobacterium tuberculosis infection ...