Plasmodium falciparum
Details about this organism
Synonyms (1)Plasmodium (Laverania) falciparum
Definitions (0)
None defined
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Strain details
| Name | Provider name | Provider's strain ID | Genotypes | Phenotypes | Synonym | Comments | Based on |
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The Snoep Lab’s core research efforts are in Computational Systems Biology; a combined experimental, modeling and theoretical approach to quantitatively understand the functional behavior of Biological Systems resulting from the characteristics of their components. Our main focus is on metabolism, of human pathogens such as Plasmodium falciparum, Mycobacterium tuberculosis, but also of breast cancer cell lines, and on modelling disease states such as glucose homeostatis in type 2 diabetes, and ...
Projects: Whole body modelling of glucose metabolism in malaria patients, Steroid biosynthesis, Yeast glycolytic oscillations, Computational pathway design for biotechnological applications, Glucose metabolism in cancer cell lines
Web page: http://www.sun.ac.za/english/faculty/science/biochemistry/research/snoep-group
Hypoglycaemia and lactic acidosis are key diagnostics for poor chances of survival in malaria patients. In this project we aim to test to what extent the metabolic activity of Plasmodium falciparum contributes to a changed glucose metabolism in malaria patients. The approach is to start with detailed bottom up models for the parasite and then merge these with more coarse grained models at the whole body level.
Programme: SARCHI: Mechanistic modelling of health and epidemiology
Public web page: Not specified
This project gathers all biomics projects submitted to biomics.pasteur.fr
Programme: Biomics Platform
Public web page: https://biomics.pasteur.fr/projects
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Glucose metabolism in Plasmodium falciparum tro...
Study: Model analysis
Inhibition of lactate flux due to glucose transport inhibitor
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Glucose metabolism in Plasmodium falciparum tro...
Study: Model analysis
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Glucose metabolism in Plasmodium falciparum tro...
Study: Model analysis
Submitter: Dawie van Niekerk
Biological problem addressed: Validation
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Submitter: Dawie van Niekerk
Biological problem addressed: Validation
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Submitter: Dawie van Niekerk
Biological problem addressed: Validation
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Submitter: Dawie van Niekerk
Biological problem addressed: Validation
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Submitter: Dawie van Niekerk
Biological problem addressed: Validation
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Inhibition of lactate flux glycolytic inhibitors
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Glucose metabolism in Plasmodium falciparum inf...
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: Mathematica
Environment: Not specified
DownloadCreators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: Mathematica
Environment: Mathematica
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: Mathematica
Environment: Mathematica
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: Mathematica
Environment: Mathematica
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
Creators: Dawie van Niekerk, Jacky Snoep
Submitter: Dawie van Niekerk
Model type: Ordinary differential equations (ODE)
Model format: Mathematica
Environment: Not specified
