Assays

What is an Assay?

10 Assays visible to you, out of a total of 10

Inhibition of glycolytic flux

Whole body modelling of glucose metabolism in malaria patients

Inhibition of lactate flux glycolytic inhibitors

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Analysis of model for malaria-infected erythroc...

Organisms: Plasmodium falciparum

Models: Glycolytic target analysis in malaria infected ..., Inhibition of glycolytic flux by glucose transp..., Kinetic model for steady state (dutoit1), Validation of lactate flux inhibition by glucos...

SOPs: No SOPs

Data files: Glycolytic flux inhibition data (erythrocytes), Lactate flux inhibition data

Snapshots: No snapshots

Created: 17th Apr 2023 at 12:26, Last updated: 18th Aug 2023 at 08:21

Flux vs external glucose

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Validation

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Validation of model for malaria-infected erythr...

Organisms: Plasmodium falciparum

Models: Flux vs glucose, Kinetic model for infected red blood cell cultu...

SOPs: No SOPs

Data files: Flux vs glucose

Snapshots: No snapshots

Created: 17th Apr 2023 at 12:21, Last updated: 18th Aug 2023 at 07:59

Steady-state

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Validation

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Validation of model for malaria-infected erythr...

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (dutoit1), Steady state (trophozoite stage)

SOPs: No SOPs

Data files: Stage specific fluxes

Snapshots: No snapshots

Created: 17th Apr 2023 at 12:18, Last updated: 18th Aug 2023 at 07:45

GLC incubation

Whole body modelling of glucose metabolism in malaria patients

SED-ML: https://jjj.bio.vu.nl/models/experiments/vanniekerk2023_fig4/simulate

Submitter: Dawie van Niekerk

Biological problem addressed: Validation

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Validation of model for malaria-infected erythr...

Organisms: Plasmodium falciparum

Models: GLC incubation timecourses, Kinetic model for incubation (dutoit2)

SOPs: No SOPs

Data files: 5 mM GLC runout data

Snapshots: No snapshots

Created: 17th Apr 2023 at 12:14, Last updated: 29th Jul 2023 at 10:33

Metabolic control analysis

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Analysis of model for malaria-infected erythroc...

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (dutoit1), MCA

SOPs: No SOPs

Data files: No Data files

Snapshots: No snapshots

Created: 26th Jul 2023 at 11:58, Last updated: 26th Jul 2023 at 12:04

Stage specific fluxes

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Validation

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Validation of model for malaria-infected erythr...

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (dutoit1), Stage specific fluxes

SOPs: No SOPs

Data files: Stage specific fluxes

Snapshots: No snapshots

Created: 17th Apr 2023 at 12:23, Last updated: 25th Apr 2023 at 16:41

Flux vs parasitaemia

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Validation

Investigation: Glucose metabolism in Plasmodium falciparum inf...

Study: Validation of model for malaria-infected erythr...

Organisms: Plasmodium falciparum

Models: Flux vs parasitaemia, Kinetic model for infected red blood cell cultu...

SOPs: No SOPs

Data files: Flux vs parasitaemia

Snapshots: No snapshots

Created: 17th Apr 2023 at 12:20, Last updated: 25th Apr 2023 at 11:52

Inhibition of glucose transport

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model analysis

Organisms: Plasmodium falciparum

Models: GLCtr kinetic model incorporating inhibition

SOPs: No SOPs

Data files: GLCtr inhibition kinetic data

Snapshots: No snapshots

Created: 2nd Jul 2015 at 10:24, Last updated: 8th Nov 2017 at 14:21

Inhibition of lactate flux

Whole body modelling of glucose metabolism in malaria patients

Inhibition of lactate flux due to glucose transport inhibitor

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model analysis

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (penkler1), Kinetic model incorporating glucose transport i..., Validation of lactate flux inhibition by glucos...

SOPs: No SOPs

Data files: Lactate flux inhibition data

Snapshots: No snapshots

Created: 2nd Jul 2015 at 10:33, Last updated: 8th Nov 2017 at 14:21

Supply-demand analysis

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model analysis

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (penkler1), Supply demand analysis on penkler1 model

SOPs: No SOPs

Data files: No Data files

Snapshots: No snapshots

Created: 10th Jul 2015 at 10:28, Last updated: 8th Nov 2017 at 14:21

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