Projects

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306 Projects found

Four ppt lecture files that are part of a UvA course on 'How to design an alien'. They correspond to four lectures given by Hans V. Westerhoff, September - October 2021

Programme: ISBE.NL service programme

Public web page: Not specified

ONT+Illumina bacterial genome assembly project

Programme: Independent Projects

Public web page: Not specified

Oxidative stress is an important mechanism of cerebral ischemia-reperfusion injury. Ferroptosis caused by iron overload after cerebral ischemia-reperfusion is considered a common cause of oxidative stress. A large number of recent studies have shown that electroacupuncture (EA) can regulate the expression of inflammatory factors, and the use of electroacupuncture preconditioning can produce a protective effect, which can reduce injury after cerebral ischemia and reperfusion. We aimed to assess ...

ORHIZON IS A PROPOSAL FOR A HORIZON EUROPE PROJECT (RIA) AIMED AT DELIVERING SOLUTIONS FOR ROOT AND RHIZOSPHERE TRAITS BASED BREEDING IN THE CONTEXT OF LOW INPUT AGRICULTURE AND CLIMAT CHANGE

Programme: Independent Projects

Public web page: Not specified

With aging comes cellular senescence, and (multi-)morbidity. Cellular senescence is a key driver of an interconnected disease network including cancer and stroke. We wish to utilize systems modeling and bioinformatics, learning from omics and other lab data, to design and develop a biomarker + software kit with a focus on measuring and interpreting senescence-related signatures for precise (and early) diagnosis, prognosis, and, ultimately, therapy, of pancreatic cancer and ischemic stroke/thromboembolism. ...

This project bundles information about COVID-19 related studies and tools in Germany. It intends to provide an information hub for the different initiatives, their aims, their processes, standards and study protocols, as well as their available data and metadata. It is initiated by the German National Research Data Infrastructure for Personal Health Data (nfdi4health), a consortium that plans to establish a concept for a federated research data infrastructure for personal health data in Germany. ...

Collection of coastal data via telemetry and sensors

Programme: Independent Projects

Public web page: https://www.afbini.gov.uk

genetical innovation

Programme: Independent Projects

Public web page: Not specified

No description specified

Programme: Testing 1, 2, 3

Public web page: Not specified

No description specified

Programme: Supplemental Data for "Why did the eyewall replacement cycle in Trami terminate rapidly? "

Public web page: Not specified

Start date: 29th Apr 2021

End date: 31st Aug 2021

No description specified

Programme: Cancer drug discovery preclinical research

Public web page: Not specified

No description specified

Programme: Gygli Group

Public web page: Not specified

Start date: 1st Nov 2019

The Hippo signalling is a metabolic control pathway of cells proliferation and apoptosis, thus represents an emerging topic in tumour suppression regulation and regenerative medicine. This pathway is activated by anti-proliferative signals which come from the extracellular environment received by membranes proteins. In the cytosol compartment, the pathway is regulated by a phosphorylation cascade of four main proteins with Serin-Treonin kinase activity. At the end-point of this cascade the ...

Programme: Cancer drug discovery preclinical research

Public web page: Not specified

OBJECTIVE: To summarise an overview of existing evidence between Chinese medicine and polycystic ovary syndrome (PCOS),and to evaluate the strength and validity of these associations. METHODS: We retrieved systematic evaluations and meta-analyses of randomized controlled trials(RCT) evaluating Chinese herbal interventions in polycystic ovaries, including the use of decoctions or Chinese patent medicines. The quality of these systematic evaluations was evaluated using AMSTAR2 tools, while ovulation ...

Programme: An overview of systematic reviews of treatment of polycystic ovary syndrome with Chinese medicine

Public web page: Not specified

Start date: 1st Dec 2020

End date: 1st May 2021

No description specified

Programme: SAFE-Aqua

Public web page: Not specified

The project "INtegrative COllaborative modeling in systems MEdicine" aims at connecting different heterogenous datasets and individual models within systems medicine.

Programme: e:med

Public web page: Not specified

Biomining is a biotechnological process carried out in many parts of the world that exploits acid loving microorganisms to extract metals from sulphide minerals. One industrial biomining method is called ‘heap bioleaching’ where typically copper containing minerals are piled into very large heaps, acid and microorganisms are added to the top and the soluble metal is collected at the heap base.

The role of the different types of microbes in the process is to speed up metal solubilisation by oxidising ...

No description specified

Programme: e:med

Public web page: https://kohlbacherlab.org

Centre for Digital Life Norway (DLN) project 'OXYMOD - Optimized oxidative enzyme systems for efficient conversion of lignocellulose to valuable products'

In this project, we integrate COVID19 Disease Maps curated regulatory information in a macrophage logical model. This allows logical simulations of the effects of acute inflammation caused by the SARS-CoV-2 virus, both in general and in a cell-specific perspective. Moreover, understanding the regulatory network behavior of macrophages following infection opens new ways to test and predict drug and drug combination effects, as a first step towards the development of new treatments.

Programme: Macrophage logical modeling

Public web page: Not specified

Start date: 1st Oct 2020

Data and experimental methods to support the work in the following paper:

Establishing Consensus Annotation for the Hallmarks of Cancer, 2020, Yi Chen, F.J.Verbeek and K.Wolstencroft, in submission

Programme: Hallmarks of cancer

Public web page: Not specified

In this project, the involved partners are trying to develop the knowledge base that will enable the breeding of new potato varieties, tolerant to multiple environmental stressors.

Programme: NIBSys

Public web page: https://adapt.univie.ac.at/

Start date: 1st Jul 2020

End date: 30th Jun 2024

Modelling COVID-19 epidemics : the training course organized by ISBE-NL, ELIXIR-LU, and EOSC-Life

Programme: Independent Projects

Public web page: https://elixir-luxembourg.org/events/2020_11_30_COVID19_modelling_training

Start date: 30th Nov 2020

End date: 31st Jan 2021

No description specified

Programme: Skin Ageing and Senescence

Public web page: Not specified

Using standard systems biology methodologies a 14-compartment dynamic model was developed for the Corona virus epidemic. The model predicts that: (i) it will be impossible to limit lockdown intensity such that sufficient herd immunity develops for this epidemic to die down, (ii) the death toll from the SARS-CoV-2 virus decreases very strongly with increasing intensity of the lockdown, but (iii) the duration of the epidemic increases at first with that intensity and then decreases again, such that ...

Programme: Model repository for M4 (Make Me My Model) clients of ISBE

Public web page: Not specified

Start date: 1st Mar 2020

End date: 24th Mar 2023

Valorization of mussel processing water into bioplastics

Programme: WooBAdh

Public web page: Not specified

Start date: 9th Nov 2020

End date: 9th Nov 2021

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

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