Projects

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306 Projects found

A joint NTNU and SINTEF project to establish a knowledge platform on DHA synthesis and lipid accumulation in the native DHA-producing thraustochytrids, and to develop these into high productivity omega-3 fatty acid producing cell factories.

Research programme in the Takato Imaizumi lab, with multiple collaborators. Published in Song et al. Nature Plants 2018; Kinmonth-Schultz et al., in silico Plant 2019.

Storage of thermophysical properties (e.g. density, viscosity, thermodynamic activity of water, conductivity) using Chemical Markup Language (CML).

Programme: This Project is not associated with a Programme

Public web page: Not specified

This project aims to develop an agent based model using the Netlogo package which can then be used for outreach in schools and the wider community. This model represents the development of breast cancer with the potential for users to explore the effects of combination treatments in silico.

Programme: Breast Cancer Simulation

Public web page: Not specified

Start date: 1st Jun 2019

End date: 1st Aug 2019

The COLOSYS project aims to develop a deeper understanding of colon cancer networks and convert them into computer models with which it will be better to predict response to treatment. The combination of computational, experimental and clinical testing will provide understanding of drug resistance mechanisms, and allow personalised treatment of colon cancer.

Programme: Druglogics

Public web page: http://www.colosys.org/

No description specified

Programme: LiSyM - Systems Medicine of the Liver

Public web page: Not specified

Web application developed using RStudio-Shiny for outreach. Incorporates information, videos and images, worksheets and simulations surrounding breast cancer development and therapy. Incorporates NetLogo simulation from "Outreach - Simulation of breast cancer development using an agent based modelling approach" project.

Programme: Breast Cancer Simulation

Public web page: Not specified

testing fairdomhub

Programme: GPSLab testing Programme

Public web page: Not specified

The gut–brain axis (GBA) provides a bidirectional homeostatic communication between the gastrointestinal tract and the central nervous system. The interdisciplinary collaboration is going to fully explore a first comprehensive GBA cross-disease map of genetic, expression and regulatory changes associated with ulcerative colitis and schizophrenia disease entities.

Dysfunction of this axis can have pathophysiological consequences. Genome-wide association studies (GWAS) have identified >300 ...

Programme: This Project is not associated with a Programme

Public web page: https://www.sbi.uni-rostock.de/research/projects/detail/49

Start date: 1st Feb 2019

End date: 12th Feb 2019

documents for use with RStudio-Shiny and java API testing

Programme: API_testing_projects

Public web page: Not specified

testing fairdom API in Java and R programming language for use in Breast cancer outreach project

Programme: API_testing_projects

Public web page: Not specified

Exploiting native endowments by re-factoring, re-programming and implementing novel control loops in Pseudomonas putida for bespoke biocatalysis. The EmPowerPutida project aims to engineer the lifestyle of Pseudomonas putida to generate a tailored, re-factored chassis for the production of so far non-accessible biological compounds. Pseudomonas putida is a bacterium with a highly versatile metabolism, including the capability to degrade or produce organic chemicals.

NAD phylogeny

Programme: This Project is not associated with a Programme

Public web page: Not specified

Start date: 30th May 2019

to complete

Programme: Independent Projects

Public web page: Not specified

please complete description

Programme: Independent Projects

Public web page: Not specified

This projects seeks to uncover how phytochrome signalling modulates leaf architecture

Programme: Halliday Lab

Public web page: http://hallidaylab.bio.ed.ac.uk/

Start date: 10th Jan 2017

How light control development

Programme: Modelling Light Control of Development

Public web page: Not specified

Start date: 1st Nov 2017

End date: 30th Nov 2021

No description specified

Programme: Independent Projects

Public web page: Not specified

BIOMICRO PROJECT TEST

Programme: KOCH

Public web page: Not specified

No description specified

Programme: Thesis AHG 2019

Public web page: Not specified

Time series response of potato cv. Désirée, which is tolerant to PVY infection, was analysed in both inoculated as well as upper non-inoculated leaves. Additionally, transgenic plants deficient in accumulation of salicylic acid (NahG- Désirée) were studied in the same setting.

This investigation is published under the CC BY 4.0 license.

Programme: NIBSys

Public web page: Not specified

INBioPharm - Integrated Novel Natural Product Discovery and Production Platform for Accelerated Biopharmaceutical Innovation from Microbial Biodiversity project will develop a new, generic technology platform for the more efficient discovery of novel bioactive compounds with improved prospects to become medical products. A unique national collection of marine microorganisms at SINTEF/NTNU will be used as the basis for the development of different new, complementary molecular biology, analytical ...

We will systematically analyse large datasets of multiple types to: (i) identify key components affected by age or experimental perturbation; (ii) establish networks of interaction; (iii) develop dynamic computational models based on these networks; (iv) use model selection methods to discriminate between alternative network topologies and generate predictive models. To characterise the data, we will apply an ensemble of methods, including frameworks in R/Bioconductor and toolboxes connected via ...

Programme: Newcastle University Systems Modelling of Ageing

Public web page: Not specified

What is PlaSMo? PlaSMo stands for Plant Systems-biology Modelling Ensuring the achievements of yesterday's Mathematical Modellers will be available for the Systems Biologists of tomorrow.

Our aims

To identify plant mathematical models useful to the UK plant systems biology community, which are currently in a variety of legacy formats and in danger of being lost

To represent these models in a declarative XML-based format, which is closer to the systems biology standard SBML To evaluate the behaviour ...

Programme: SynthSys

Public web page: Not specified

No description specified

Programme: MS_DILI

Public web page: Not specified

Extremophiles metabolsim

Programme: Independent Projects

Public web page: Not specified

There is an urgent need for novel antibiotics to fight life-threatening infections and to counteract the increasing problem of propagating antibiotic resistance. Recently, new molecular genetic and biochemical tools have provided insight into the enormous unexploited genetic pool of environmental microbial biodiversity for new antibiotic compounds. New tools for more efficiently lifting this hidden treasure are needed to strengthen competitiveness of European industry, as well as for a cost-saving ...

Global metabolic switching in Streptomyces coelicolor

Antibiotics are made during the second phase of growth when there is a transition in metabolism from primary to secondary metabolism. Primary metabolism is growth related and involves all the normal cellular activities associated with cell growth and division. Whereas secondary metabolism is non-growth linked and is non-essential but many important activities occur during this phase which help the bacterium survive.

Programme: SysMO

Public web page: Not specified

No description specified

Programme: The Novo Nordisk Foundation Center for Biosustainability

Public web page: Not specified

The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:

  • facilitates and maximises the potential for data exchange between SysMO research groups;
  • maximises the ‘shelf life’ and ...

Programme: SysMO

Public web page: http://www.sysmo-db.org/

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