Projects

Collaboration with Miltos Tsiantis for reconstructing RCO transcriptional regulation

improvement of PULSE, derivation of tools for ontogenetic control of interesting pathways

Modulation of light, temperature and time networks using prime editing and mathematical modelling

Test project to see Fairdom capabilities.

Designing 3D metamaterials

This project aims to develop an agent based model using the Netlogo package which can then be used for outreach in schools and the wider community. This model represents cellular senescence in skin with the potential for users to explore the effects of combination treatments in silico.

Web application developed using RStudio-Shiny for outreach. Incorporates information, videos and images, worksheets and simulations surrounding cellular senescence and therapy. Incorporates NetLogo simulation from "Outreach - Simulation of cellular senescence using an agent based modelling approach" project.

Overall, we will measure in-vitro and model in-silico the short-term biochemical network dynamics of extra cellular matrix maintenance (ECM) in populations of young, old and senescent dermal fibroblasts. We have shown in previous work that differences in network dynamics are highly informative and provide a means to identify parts of the network that could be targeted to restore healthy function.

The work will be first carried out in 2D culture of human dermal fibroblasts then extended to a novel ...

This project gathers all biomics projects submitted to biomics.pasteur.fr

Using MCA to understand which enzymes have higher impact in Acetyl-coa production in P. putida

DeepHyperSpec: Combining spectral and image information in the analysis of hyperspectral imaging data Infrared microspectroscopic imaging is a new technique for rapid, label-free and automated diagnosis of various types of cancer. The technique is expected to enter clinical routine analysis in the years coming.

Understanding the molecular basis of diseases can shed light into new methods to manage and cure diseases. Exploring the common or unique molecular mechanisms among a group of diseases may enhance our understanding of each disease or uncover therapeutic approaches that can be effective in multiple diseases. In this project we develop methods that use biological networks and known gene-disease associations to identify common molecular mechanisms associated across multiple diseases.

Testing stuff

Centre for Environment-friendly Energy Research Research in the past decade has shown that biomass conversion into energy fuels and other value added products, in contrast to traditional refineries, requires highly integrated versatile plants. In most cases, such plants will need to produce a portfolio of products that together secure economic sustainability. The Centre for Environment-friendly Energy Research aims to develop innovative technology and support industries to realize economic and ...

Bioconversion of low-cost fat materials into high-value PUFA-Carotenoid-rich biomass The project aims at upgrading Norwegian animal slaughter fat by-products to high-value fatty acids by fungal fermentation processes.

generation of a toggle switch based on a non-cooperative network

A project created for demonstration

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This project aims to develop an agent based model using the Netlogo package which can then be used for outreach in schools and the wider community. This model represents the development of breast cancer with the potential for users to explore the effects of combination treatments in silico.