Mycoplasma pneumoniae
Details about this organism
Synonyms (2)Filterable agent of primary atypical pneumonia, Schizoplasma pneumoniae
Definitions (0)
None defined
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Strain details
| Name | Provider name | Provider's strain ID | Genotypes | Phenotypes | Synonym | Comments | Based on |
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The MycoSynVac project AIMS at using cutting-edge synthetic biology methodologies to engineer Mycoplasma pneumoniae as a universal chassis for vaccination.
Designing a universal Mycoplasma chassis that can be deployed as single- or multi-vaccine in a range of animal hosts. Annually, infections caused by Mycoplasma species in poultry, cows, and pigs result in multimillion Euro losses in the USA and Europe.
There is no effective vaccination against many Mycoplasmas that infect pets, humans and farm
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Programme: Independent Projects
Public web page: http://www.mycosynvac.eu/
Dynamic model of glycolysis, pyruvate metabolism and ATPase. Initial parameters values for Monod and allosteric control constants were taken from the L. lactis model from Costa et al. since no MPN specific measurements were available. Vmax values are based on MPN growth curve data. The model is annotated with MIRIAM compliant annotation and SBO numbers.
Creator: Niels Zondervan
Contributor: Niels Zondervan
Model type: Ordinary differential equations (ODE)
Model format: SBML
Environment: Not specified
DownloadCore model with the addition of a NoxE reaction to regenerate NAD using O2. COPASI’s build in Evolutionary programming algorithm was used to estimate parameters using a maximum of 2000 generations with a population size of 100 models with value scaling as weights to train the 5 parameters of the NoxE reaction.
Creator: Niels Zondervan
Contributor: Niels Zondervan
Model type: Not specified
Model format: Copasi
Environment: Copasi
