Modelling of M. pneumoniae metabolism

1. To develop a whole-cell dynamic model framework of the metabolism of M. pneumoniae
2. To build upon M. pneumoniae models to develop a genome-scale, constraint-based model of M.
hyopneumoniae for vaccine optimization
3. To deploy the metabolic model(s) to: 1) the rational design and optimization of the vaccine chassis; 2)
aid the development of a higher-growth rate chassis; 3) assist the development of a nutrient optimized a
serum-free growth medium and; 4) assess, at genome scale, the metabolic capabilities of a series of
Mycoplasmas with the purpose of designing a tailored vaccine portfolio

help Creators and Submitter
Zondervan, N. (2019). Modelling of M. pneumoniae metabolism. FAIRDOMHub.
Note: This is a citation for Snapshot 3 of this Investigation, the contents of which may vary from what is shown on this page.
Snapshot 3 (20th Nov 2019) DOI
Snapshot 2 (14th Jan 2019) DOI
Snapshot 1 (14th Jan 2019) DOI

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Created: 18th Apr 2017 at 16:51

Last updated: 20th Nov 2019 at 00:19

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